Protein Alignment ZnT35C and slc30a8

DIOPT Version :9

• Sequence 1: NP_609741.3
• Gene: ZnT35C / 34890
• FlyBaseID: FBgn0028516
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_001011041.1
• Gene: slc30a8 / 496450
• XenbaseID: XB-GENE-958127
• Length: 374
• Species: Xenopus tropicalis
• Alignment Length: 433
• Identity: 165/433 - (38%)
• Similarity: 231/433 - (53%)
• Gaps: 89/433 - (20%)

  Fly    44 NGNNNHPATPATPAQIFCLHGRSNNVEVRDHCHRARSEGVDVK------ARRKLIIASILCLVFM 102
            :...|||:.|  |.|      ...|.:.:.|||....:..|.:      |::||.|||::|.||:
 Frog    23 DSEKNHPSKP--PLQ------DEENPQSKYHCHNNNKKAYDARQREQTFAKKKLCIASLICFVFI 79

  Fly   103 IAEIVGGVLSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPSTQRMSFGWYRAEVIGAMASVFM 167
            .||||||.::.|||:.|||||||.|.:||.|||.::|::.:.||.|::|||:|||::||:.||..
 Frog    80 SAEIVGGYIAGSLAVVTDAAHLLVDLSSFFISLCSLWLSSKSSTTRLTFGWHRAEILGALMSVIT 144

  Fly   168 IWVITGILVWLAIGRLISGDYEVNAKIMLITSGLAILVNVIMGVQLQHGHSHGLGGGHGHSHGGS 232
            ||::||:||:||..|||..||.::..:|||||..|:..|:::.:.|..       .||||||.|
 Frog   145 IWLVTGVLVYLACERLIRPDYTIDGTVMLITSACALGANLVLALILHQ-------SGHGHSHAG- 201

  Fly   233 KNASHVQATSTPCSDSPSQRIEGGVAYAPEDAELPGGGLPTFSYQNTKLVDPTLDLEIAAVLAET 297
                                                                             
 Frog   202 ----------------------------------------------------------------- 201

  Fly   298 APGSHHHGGPVGREAVNMNVRAALIHVIGDVIQSVGVFVAAGVIYFWPEYSIVDPICTFVFSIIV 362
              |.|.|.....:...|.::|||.||||||:.||:.|.::|.:|||.|||.:.||||||:|||.|
 Frog   202 --GKHEHMASEYKPQTNASIRAAFIHVIGDLFQSISVLISALIIYFKPEYKMADPICTFIFSIFV 264

  Fly   363 LFTTFTIMKDALLVLMEGTPNYMHYAEVLQIFQGIEGVERVHNLRIWALSINKVALSAHLAIAEN 427
            |.||.|:::|.|.|||||||..:||::|.|....::||:.||:|.:|||::|:|.||||:|....
 Frog   265 LITTVTVLRDLLTVLMEGTPRGIHYSDVKQSILAVDGVKSVHSLHLWALTMNQVILSAHIATDIV 329

  Fly   428 ANPKRILDAATSAVHLRYNFFETTIQIEDYTAQMESCLQCNVP 470
            ...||||...|..|..|:.|...|||:|....|...|:.|..|
 Frog   330 GESKRILKDVTQNVFARFPFHSVTIQVEPIEDQSPECMFCYEP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT35C	NP_609741.3	CDF	100..457	CDD:273544	143/356 (40%)
		Cation_efflux	100..378	CDD:279834	106/277 (38%)
slc30a8	NP_001011041.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..48		9/32 (28%)
		CDF	77..358	CDD:273544	142/355 (40%)
		Cation_efflux	77..280	CDD:279834	106/277 (38%)
		HXXXXX[HY]NH-motif	191..199		4/14 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	337	1.000	Inparanoid score	I2337
OMA	1	1.010	-	-		QHG53838
OrthoDB	1	1.010	-	-		D351752at33208
OrthoFinder	1	1.000	-	-		FOG0000470
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11562
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3917
SonicParanoid	1	1.000	-	-		X541
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.110