Protein Alignment ZnT35C and slc30a2

DIOPT Version :9

• Sequence 1: NP_609741.3
• Gene: ZnT35C / 34890
• FlyBaseID: FBgn0028516
• Length: 472
• Species: Drosophila melanogaster
• Sequence 2: NP_001006823.1
• Gene: slc30a2 / 448552
• XenbaseID: XB-GENE-494395
• Length: 377
• Species: Xenopus tropicalis
• Alignment Length: 428
• Identity: 187/428 - (43%)
• Similarity: 252/428 - (58%)
• Gaps: 94/428 - (21%)

  Fly    57 AQIFCLHGRSNNVEV----RDHCHRARSEGVD-------VKARRKLIIASILCLVFMIAEIVGGV 110
            :|:|......|.:|:    ..|||..|.  :|       .:|||||.:||.:||||||.|::||.
 Frog    28 SQVFTYISDLNGIELGHQGNQHCHSNRE--LDDWNAKEKKRARRKLYVASAVCLVFMIGEVIGGY 90

  Fly   111 LSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPSTQRMSFGWYRAEVIGAMASVFMIWVITGIL 175
            |::||||.||||||||||||.||||||:|::.||:|:.|:|||:|||::||:.||..|||:||:|
 Frog    91 LAHSLAIMTDAAHLLTDFASMMISLFALWMSSRPATKTMNFGWHRAEILGALLSVLSIWVVTGVL 155

  Fly   176 VWLAIGRLISGDYEVNAKIMLITSGLAILVNVIMGVQLQ---HGHSHGLGGGHGHSHGGSKNASH 237
            |:||:.|:||||||:....|||||..|:.||:||||.|.   ||||||.|..|.|||
 Frog   156 VYLAVERIISGDYEIEGDAMLITSACAVAVNIIMGVTLHQTGHGHSHGDGNSHSHSH-------- 212

  Fly   238 VQATSTPCSDSPSQRIEGGVAYAPEDAELPGGGLPTFSYQNTKLVDPTLDLEIAAVLAETAPGSH 302
                                                                        |.|.|
 Frog   213 ------------------------------------------------------------AAGDH 217

  Fly   303 HHGGPVGREAVNMNVRAALIHVIGDVIQSVGVFVAAGVIYFWPEYSIVDPICTFVFSIIVLFTTF 367
            .          |.:||||.|||:||::|||||.:||.|||:.|||.|:||||||:||::||.||.
 Frog   218 K----------NPSVRAAFIHVVGDLLQSVGVLIAAYVIYYKPEYKIIDPICTFLFSVLVLITTL 272

  Fly   368 TIMKDALLVLMEGTPNYMHYAEVLQIFQGIEGVERVHNLRIWALSINKVALSAHLAIAENANPKR 432
            ||::|.|||||||||..:.:..|......|:||:.:|:|.||||::.:..||.|:||.|||:.::
 Frog   273 TILRDVLLVLMEGTPKGVDFNLVKDTLLSIDGVKALHSLHIWALTVTQPVLSVHIAINENADSQK 337

  Fly   433 ILDAATSAVHLRYNFFETTIQIEDYTAQMESCLQCNVP 470
            :|..|:|.:..:::|..||||||:|:..|:.|.:|..|
 Frog   338 VLKEASSQLQNKFHFHTTTIQIENYSDDMKDCQECQDP 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT35C	NP_609741.3	CDF	100..457	CDD:273544	164/359 (46%)
		Cation_efflux	100..378	CDD:279834	130/280 (46%)
slc30a2	NP_001006823.1	CDF	80..362	CDD:273544	164/359 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I7064
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H40855
Inparanoid	1	1.050	337	1.000	Inparanoid score	I2337
OMA	1	1.010	-	-		QHG53838
OrthoDB	1	1.010	-	-		D351752at33208
OrthoFinder	1	1.000	-	-		FOG0000470
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11562
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3917
SonicParanoid	1	1.000	-	-		X541
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	11.110