DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4168 and Lrrc4

DIOPT Version :9

Sequence 1:NP_001285953.1 Gene:CG4168 / 34889 FlyBaseID:FBgn0028888 Length:1330 Species:Drosophila melanogaster
Sequence 2:NP_001032413.1 Gene:Lrrc4 / 641521 RGDID:1560026 Length:652 Species:Rattus norvegicus


Alignment Length:481 Identity:116/481 - (24%)
Similarity:191/481 - (39%) Gaps:145/481 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   433 SLHH------LKYLYLT---------------------------SNQISQ-------LNNLP-SF 456
            ::||      |..:|||                           |||.|:       |:.:| ..
  Rat     8 TVHHTWNAVLLPVVYLTAQVWILCAAIAAAASAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGI 72

  Fly   457 TENLRVLSLSGNNFSMIPVLGLKNYTQLSYLNMGYNSITDIPEGIFAVDSWGSNLQTILLRNNKI 521
            ..|.|.|:|..||..||.....::...|..|.:|.|:|..|..|.|   :..::|.|:.|.:|.:
  Rat    73 PSNTRYLNLMENNIQMIQADTFRHLHHLEVLQLGRNAIRQIEVGAF---NGLASLNTLELFDNWL 134

  Fly   522 THLHLGSFAGLEQIQEISLSFNDITIHHPLVFENVSRTLKILELSFAVFPARSLESLDPLDALLP 586
            |.:..|:|..|.:::|:.|..|.|        |::.        |:|.....||..||       
  Rat   135 TVIPSGAFEYLSKLRELWLRNNPI--------ESIP--------SYAFNRVPSLMRLD------- 176

  Fly   587 LSQLIWLGLDNNNLKQVSNESFAQMRELSYINLSFNQLKTLPR-----GLFQSDAHSHLVEIDLS 646
            |.:|       ..|:.:|..:|..:..|.|:||....:|.:|.     |         |.|:::|
  Rat   177 LGEL-------KKLEYISEGAFEGLFNLKYLNLGMCNIKDMPNLTPLVG---------LEELEMS 225

  Fly   647 YNGLERLEAQTFHSLGDLQTLNLQSNRLRTIARHAFHNLEFLRYLDLSYNRLVNISHGAFTVLPN 711
            .|....:...:||.|..|:.|.:.::::..|.|:||..|..|..|:|::|.|.::.|..||.|..
  Rat   226 GNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLAHNNLSSLPHDLFTPLRY 290

  Fly   712 LAALDLMHNQL---CSLS-----LKSFLYVSNTT-----TPLRLNVSHNHIASFY----DELS-- 757
            |..|.|.||..   |.:.     |:.::..::|.     .|:       |:...|    |:.|  
  Rat   291 LVELHLHHNPWNCDCDILWLAWWLREYIPTNSTCCGRCHAPM-------HMRGRYLVEVDQASFQ 348

  Fly   758 -SYMYIY----QLDISHNHVTKSDSFTNLANTLRFLNLAHNQLGSLQSHAF----------GDLE 807
             |..:|.    .|:||.:.:.:....|...:::::| |.:   |::.|||.          |.|.
  Rat   349 CSAPFIMDAPRDLNISEDRMAELKCRTPPMSSVKWL-LPN---GTVLSHASRHPRISVLNDGTLN 409

  Fly   808 FLEIL------------NVAHNNLTS 821
            |..:|            |||.|:..|
  Rat   410 FSRVLLIDTGVYTCMVTNVAGNSNAS 435

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4168NP_001285953.1 leucine-rich repeat 99..118 CDD:275380
LRR_8 121..181 CDD:290566
LRR_RI 122..350 CDD:238064
leucine-rich repeat 122..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..194 CDD:275380
leucine-rich repeat 195..214 CDD:275380
leucine-rich repeat 215..236 CDD:275380
LRR_8 265..322 CDD:290566
leucine-rich repeat 266..287 CDD:275380
leucine-rich repeat 288..311 CDD:275380
leucine-rich repeat 312..338 CDD:275380
LRR_RI 315..546 CDD:238064 39/153 (25%)
leucine-rich repeat 339..365 CDD:275380
LRR_8 365..424 CDD:290566
leucine-rich repeat 366..388 CDD:275380
leucine-rich repeat 389..412 CDD:275380
LRR_8 413..470 CDD:290566 17/77 (22%)
leucine-rich repeat 414..436 CDD:275380 0/2 (0%)
leucine-rich repeat 437..459 CDD:275380 10/56 (18%)
leucine-rich repeat 460..483 CDD:275380 7/22 (32%)
LRR_8 482..545 CDD:290566 19/62 (31%)
leucine-rich repeat 484..510 CDD:275380 8/25 (32%)
leucine-rich repeat 511..534 CDD:275380 8/22 (36%)
leucine-rich repeat 535..589 CDD:275380 12/53 (23%)
LRR_RI 588..891 CDD:238064 68/285 (24%)
LRR_8 588..650 CDD:290566 15/66 (23%)
leucine-rich repeat 590..613 CDD:275380 4/22 (18%)
leucine-rich repeat 614..639 CDD:275380 7/29 (24%)
LRR_8 638..698 CDD:290566 18/59 (31%)
leucine-rich repeat 640..663 CDD:275380 7/22 (32%)
leucine-rich repeat 664..687 CDD:275380 7/22 (32%)
LRR_8 688..749 CDD:290566 18/73 (25%)
leucine-rich repeat 688..711 CDD:275380 9/22 (41%)
leucine-rich repeat 712..735 CDD:275380 7/30 (23%)
leucine-rich repeat 740..783 CDD:275380 10/53 (19%)
LRR_8 784..843 CDD:290566 15/60 (25%)
leucine-rich repeat 785..808 CDD:275380 8/32 (25%)
leucine-rich repeat 809..832 CDD:275380 6/25 (24%)
LRR_RI <827..1053 CDD:238064
LRR_8 832..890 CDD:290566
leucine-rich repeat 833..856 CDD:275380
leucine-rich repeat 857..879 CDD:275380
leucine-rich repeat 880..900 CDD:275380
LRR_8 904..963 CDD:290566
leucine-rich repeat 905..928 CDD:275380
leucine-rich repeat 929..952 CDD:275380
leucine-rich repeat 953..977 CDD:275380
leucine-rich repeat 978..1020 CDD:275380
LRR_8 1019..1074 CDD:290566
leucine-rich repeat 1045..1068 CDD:275380
leucine-rich repeat 1069..1090 CDD:275380
leucine-rich repeat 1091..1114 CDD:275380
leucine-rich repeat 1115..1161 CDD:275380
leucine-rich repeat 1162..1190 CDD:275380
Lrrc4NP_001032413.1 LRRNT 45..78 CDD:214470 7/32 (22%)
LRR_8 74..132 CDD:404697 19/60 (32%)
LRR 1 75..96 8/20 (40%)
leucine-rich repeat 76..99 CDD:275380 7/22 (32%)
PPP1R42 96..300 CDD:411060 66/245 (27%)
LRR 2 99..120 8/23 (35%)
leucine-rich repeat 100..123 CDD:275380 8/25 (32%)
LRR 3 123..144 7/20 (35%)
leucine-rich repeat 124..147 CDD:275380 8/22 (36%)
LRR 4 147..168 7/36 (19%)
leucine-rich repeat 148..171 CDD:275380 7/38 (18%)
LRR 5 171..193 9/35 (26%)
leucine-rich repeat 172..196 CDD:275380 8/37 (22%)
LRR 6 196..217 6/20 (30%)
leucine-rich repeat 197..218 CDD:275380 6/20 (30%)
LRR 7 218..239 6/29 (21%)
leucine-rich repeat 219..242 CDD:275380 7/22 (32%)
LRR 8 242..263 6/20 (30%)
leucine-rich repeat 243..266 CDD:275380 7/22 (32%)
LRR 9 266..287 7/20 (35%)
leucine-rich repeat 267..288 CDD:275380 8/20 (40%)
LRRCT 299..350 CDD:214507 9/57 (16%)
IG_like 358..440 CDD:214653 19/82 (23%)
Ig strand B 369..373 CDD:409353 0/3 (0%)
Ig strand C 380..384 CDD:409353 0/3 (0%)
Ig strand E 406..410 CDD:409353 2/3 (67%)
Ig strand F 420..425 CDD:409353 0/4 (0%)
Ig strand G 433..436 CDD:409353 1/3 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

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