DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4168 and lrig2

DIOPT Version :9

Sequence 1:NP_001285953.1 Gene:CG4168 / 34889 FlyBaseID:FBgn0028888 Length:1330 Species:Drosophila melanogaster
Sequence 2:XP_021332954.1 Gene:lrig2 / 571101 ZFINID:ZDB-GENE-041111-75 Length:1044 Species:Danio rerio


Alignment Length:720 Identity:161/720 - (22%)
Similarity:278/720 - (38%) Gaps:191/720 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   379 LPEAVFKATGIAHLVLAFNAISRV-HPSAFEGLTETLEYLDLERNRLTTVPVALSSLHHLKYLYL 442
            :|:|:|.      |:::...:... .|.:..|.....:.||..|.|||.  .||.:...:.:..:
Zfish     7 IPQALFL------LIVSVVGLDTCPSPCSCSGGPGAAQLLDCNRKRLTA--AALEAPAWVTHASI 63

  Fly   443 TSNQISQLNNLPSFTENLRVLSLSGNNFSMIPVLGLKNYTQLSYLNMGYNSITDIPEGIFAVDSW 507
            ..|:::.:..|...:.|:.||||..|..|.:....|..|                          
Zfish    64 NQNELTAVPFLGDASSNITVLSLVHNRISEVVAEQLLPY-------------------------- 102

  Fly   508 GSNLQTILLRNNKITHLHLGSFAGLEQIQEISLSFNDITIHHPLVFENVSR--TLKILELSFAVF 570
             |:|:::.|.:|.|:.|..|||..: |::.::||.|.|:...|..|.|:|.  .|||.:...::.
Zfish   103 -SSLESLDLSSNSISELKAGSFPPM-QLKYLNLSKNKISSLEPGCFGNISSLLVLKINQNRLSLL 165

  Fly   571 PARSLESLDPLDALLPLSQLIWLGLDNNNLKQVSNESFAQMRELSYINLSFNQLKTLPRG-LFQS 634
            |          |.:..||||..|.|..|.::.|.:..|.:::.|..:.:..|.:..|..| ||..
Zfish   166 P----------DKVFTLSQLQVLELRRNRIRVVESLIFKELKALKSLKMQRNGITKLMDGALFGL 220

  Fly   635 DAHSHLVEIDLSYNGLERLEAQTFHSLGDLQTLNLQSNRLRTIARHAFHNLEFLRYLDLSYNRLV 699
            :   ::.|::|.||.|..|.....:.|..|:.|.:..|.:..|...|:.....|..||||:|.|.
Zfish   221 E---NMEELELEYNNLTELNKGWLYGLHMLRILRVNQNNIGLIRADAWEFCHRLEELDLSFNHLS 282

  Fly   700 NISHGAFTVLPNLAALDLMHNQLCSLSLKSFLYVSNTTTPLRLNVSHNHIASFYDELSSYMYIYQ 764
            .:....|..|..|.:|:|..||:..|....|..::|..|                          
Zfish   283 RLEDWVFAGLSLLQSLNLGDNQISHLGEGVFSSLANVRT-------------------------- 321

  Fly   765 LDISHNHVTKS-DSFTNLANTLRFLNLAHNQLGSLQSHAFGDLEFLEILNVAHNNLTSLRRRSFQ 828
            |||.:|.::.: :.|..:                     |..|:.|..|.:.:|.:.::.:|:|:
Zfish   322 LDIRNNEISLAIEDFIGM---------------------FVGLKRLNSLVLQNNKIRTITKRAFE 365

  Fly   829 GLNSLQELDLSHNQLDQLQVEQFSNLRKLRILRINSNRLR------------------------- 868
            ||..|:.||||.|.:..:..:.|::| ||:.|.:||:.|.                         
Zfish   366 GLMELENLDLSKNGIMSIHPDAFTHL-KLKTLDLNSSSLLCDCQLQWLGQWLINSRFQQSCTAVC 429

  Fly   869 ALPREVFMNTRL-----EFL--DIAENQLSVWPVPAFTDIGFTLRSIQMSHNNLEYLDASMFINS 926
            |.|..:..::.|     ||:  |..:.|::..|..|     ..||...::      |:.|.|.:|
Zfish   430 AHPASLAGSSVLAVKPEEFVCSDFPKPQITAHPKTA-----VALRGTNVT------LNCSAFSSS 483

  Fly   927 ------------QFLYDISL---ARNRITILPDNTFSFLNNLTNLDLSQNPLVTTNLREVFVHTP 976
                        :.||:..:   ||.:...|...|...|.|:...|..|...|.:|  ....:..
Zfish   484 DSPMSTAWRKDGEVLYEAQVQNYARYQDQRLLYTTILHLLNVNFTDEGQYQCVLSN--HFGSNYS 546

  Fly   977 RLRKLSLHHMGLYVLPPLKLPLLSYLDVSGNYLQELSPLGSLRHLRHVNVSHNKLTNASCAAE-H 1040
            .|.||:::.:..::..|:.|.:.:               |::..|             .|||| |
Zfish   547 TLAKLTVNELPTFLKTPMDLTIRT---------------GTVARL-------------ECAAEGH 583

  Fly  1041 LPPSV 1045
            ..|.:
Zfish   584 PTPQI 588

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4168NP_001285953.1 leucine-rich repeat 99..118 CDD:275380
LRR_8 121..181 CDD:290566
LRR_RI 122..350 CDD:238064
leucine-rich repeat 122..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..194 CDD:275380
leucine-rich repeat 195..214 CDD:275380
leucine-rich repeat 215..236 CDD:275380
LRR_8 265..322 CDD:290566
leucine-rich repeat 266..287 CDD:275380
leucine-rich repeat 288..311 CDD:275380
leucine-rich repeat 312..338 CDD:275380
LRR_RI 315..546 CDD:238064 38/167 (23%)
leucine-rich repeat 339..365 CDD:275380
LRR_8 365..424 CDD:290566 9/45 (20%)
leucine-rich repeat 366..388 CDD:275380 3/8 (38%)
leucine-rich repeat 389..412 CDD:275380 3/23 (13%)
LRR_8 413..470 CDD:290566 16/56 (29%)
leucine-rich repeat 414..436 CDD:275380 8/21 (38%)
leucine-rich repeat 437..459 CDD:275380 2/21 (10%)
leucine-rich repeat 460..483 CDD:275380 8/22 (36%)
LRR_8 482..545 CDD:290566 13/62 (21%)
leucine-rich repeat 484..510 CDD:275380 0/25 (0%)
leucine-rich repeat 511..534 CDD:275380 8/22 (36%)
leucine-rich repeat 535..589 CDD:275380 14/55 (25%)
LRR_RI 588..891 CDD:238064 79/336 (24%)
LRR_8 588..650 CDD:290566 18/62 (29%)
leucine-rich repeat 590..613 CDD:275380 6/22 (27%)
leucine-rich repeat 614..639 CDD:275380 6/25 (24%)
LRR_8 638..698 CDD:290566 18/59 (31%)
leucine-rich repeat 640..663 CDD:275380 7/22 (32%)
leucine-rich repeat 664..687 CDD:275380 5/22 (23%)
LRR_8 688..749 CDD:290566 18/60 (30%)
leucine-rich repeat 688..711 CDD:275380 9/22 (41%)
leucine-rich repeat 712..735 CDD:275380 7/22 (32%)
leucine-rich repeat 740..783 CDD:275380 5/43 (12%)
LRR_8 784..843 CDD:290566 15/58 (26%)
leucine-rich repeat 785..808 CDD:275380 2/22 (9%)
leucine-rich repeat 809..832 CDD:275380 7/22 (32%)
LRR_RI <827..1053 CDD:238064 57/267 (21%)
LRR_8 832..890 CDD:290566 20/89 (22%)
leucine-rich repeat 833..856 CDD:275380 8/22 (36%)
leucine-rich repeat 857..879 CDD:275380 7/46 (15%)
leucine-rich repeat 880..900 CDD:275380 7/26 (27%)
LRR_8 904..963 CDD:290566 16/73 (22%)
leucine-rich repeat 905..928 CDD:275380 6/34 (18%)
leucine-rich repeat 929..952 CDD:275380 7/25 (28%)
leucine-rich repeat 953..977 CDD:275380 4/23 (17%)
leucine-rich repeat 978..1020 CDD:275380 6/41 (15%)
LRR_8 1019..1074 CDD:290566 7/28 (25%)
leucine-rich repeat 1045..1068 CDD:275380 0/1 (0%)
leucine-rich repeat 1069..1090 CDD:275380
leucine-rich repeat 1091..1114 CDD:275380
leucine-rich repeat 1115..1161 CDD:275380
leucine-rich repeat 1162..1190 CDD:275380
lrig2XP_021332954.1 NEL <7..>191 CDD:330839 56/229 (24%)
leucine-rich repeat 38..57 CDD:275380 8/20 (40%)
leucine-rich repeat 58..81 CDD:275380 2/22 (9%)
leucine-rich repeat 83..104 CDD:275380 8/47 (17%)
PLN00113 <128..>403 CDD:331614 85/335 (25%)
leucine-rich repeat 128..151 CDD:275380 7/22 (32%)
leucine-rich repeat 152..174 CDD:275380 6/31 (19%)
leucine-rich repeat 175..198 CDD:275380 6/22 (27%)
leucine-rich repeat 199..246 CDD:275380 13/49 (27%)
leucine-rich repeat 247..270 CDD:275380 5/22 (23%)
LRR_8 270..329 CDD:316378 22/84 (26%)
leucine-rich repeat 271..294 CDD:275380 9/22 (41%)
leucine-rich repeat 295..318 CDD:275380 7/22 (32%)
leucine-rich repeat 319..345 CDD:275380 8/72 (11%)
leucine-rich repeat 346..369 CDD:275380 7/22 (32%)
leucine-rich repeat 370..391 CDD:275380 7/20 (35%)
LRRCT 403..451 CDD:214507 6/47 (13%)
Ig 459..553 CDD:325142 23/106 (22%)
Ig_1 574..648 CDD:143240 7/28 (25%)
I-set 651..738 CDD:254352
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4194
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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