DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4168 and Tl

DIOPT Version :10

Sequence 1:NP_609740.4 Gene:CG4168 / 34889 FlyBaseID:FBgn0028888 Length:1330 Species:Drosophila melanogaster
Sequence 2:NP_001262995.1 Gene:Tl / 43222 FlyBaseID:FBgn0262473 Length:1117 Species:Drosophila melanogaster


Alignment Length:998 Identity:212/998 - (21%)
Similarity:355/998 - (35%) Gaps:340/998 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   410 LTETLEYLDLERN-RLTTV--------------PVALSSLHHLKY--------------LYLTSN 445
            ||:|.:|..|.:. |:..|              |:| |.|.:|..              :.:|..
  Fly    81 LTDTTDYQQLPKKLRIGEVDRVQMRRCMLPGHTPIA-SILDYLGIVSPTTLIFESDNLGMNITRQ 144

  Fly   446 QISQLNNLPSFTENLRVLSLSGNNFSMIPVLGLKNYTQLSYLNMGYNSITDIPEGIFAVDSWGSN 510
            .:.:|:.|..|....|.|       :.||...|.:...||:|.:..| |.::|..:|  |.. .|
  Fly   145 HLDRLHGLKRFRFTTRRL-------THIPANLLTDMRNLSHLELRAN-IEEMPSHLF--DDL-EN 198

  Fly   511 LQTILLRNNKITHLHLGSFAGLEQIQEISL---SFNDITIHHPLVFENVSRTLKILELSFAVFPA 572
            |::|...:||:..:..|.|..:.::::::|   ..:::|.|.   ||..:..             
  Fly   199 LESIEFGSNKLRQMPRGIFGKMPKLKQLNLWSNQLHNLTKHD---FEGATSV------------- 247

  Fly   573 RSLESLDPLDALLPLSQLIWLGLD--NNNLKQVSNESFAQMRELSYINLSFNQLKTLPRGLFQSD 635
                                ||:|  :|.::|:.::.||.:..::.||||.|..::||:|||  |
  Fly   248 --------------------LGIDIHDNGIEQLPHDVFAHLTNVTDINLSANLFRSLPQGLF--D 290

  Fly   636 AHSHLVEIDLSYN--GLERLEAQTFHSLGDLQTLNLQSNRLRTIARHAFHNLEFLRYLDLSYNRL 698
            .:.||.|:.|..|  .|..|.::.|.:..:||.|.|:: .|:::....|.:...:..:.|..|.|
  Fly   291 HNKHLNEVRLMNNRVPLATLPSRLFANQPELQILRLRA-ELQSLPGDLFEHSTQITNISLGDNLL 354

  Fly   699 VNISHGAFTVLPNLAALDLMHNQLCSLSLKSFLYVSNTTTPLRLNVSHNHIASFYDELSSYMYIY 763
            ..:.........||.:|||.:|:|..|....|.:.:|.|                          
  Fly   355 KTLPATLLEHQVNLLSLDLSNNRLTHLPDSLFAHTTNLT-------------------------- 393

  Fly   764 QLDISHNHVT--KSDSFTNLANTLRFLNLAHNQLGSLQSHAFGDLEFLEILNVAHNNLTSLRRRS 826
            .|.:..|.:|  ..|.|:||.|                         |..|.::.|.|.::..|:
  Fly   394 DLRLEDNLLTGISGDIFSNLGN-------------------------LVTLVMSRNRLRTIDSRA 433

  Fly   827 FQGLNSLQELDLSHNQLD----------QLQVEQ-FSNLRKLRILRINSNRLRALPREVFM---- 876
            |...|.|:.|.|.||.:|          |.|:.. |..:..|..|.:.:|.:      :|:    
  Fly   434 FVSTNGLRHLHLDHNDIDLQQPLLDIMLQTQINSPFGYMHGLLTLNLRNNSI------IFVYNDW 492

  Fly   877 -NTRLEFLDIAENQLSVWPVPAFTDIGFTLRSIQMSHNN---LEYLDASMFINSQFLYDISLARN 937
             ||.|:                       ||.:.:|:||   |.|.|.: |::...|: :::..|
  Fly   493 KNTMLQ-----------------------LRELDLSYNNISSLGYEDLA-FLSQNRLH-VNMTHN 532

  Fly   938 RI--TILPDNTF---SFLNNLTNLDLSQNPLVTTNLREVF------VHTPRL-RKLSLHHMGLYV 990
            :|  ..||::..   .:.|||.::||:.||||.......|      ||.|:. |:..|....|..
  Fly   533 KIRRIALPEDVHLGEGYNNNLVHVDLNDNPLVCDCTILWFIQLVRGVHKPQYSRQFKLRTDRLVC 597

  Fly   991 LPPLKL-----------PLLSYLDVSGNYLQELSPLGSLRHLRHVNVSHNKLTNASCAAEHLPPS 1044
            ..|..|           .|:..||.|.:..:...|.|...|:|    :::|....:|.:.     
  Fly   598 SQPNVLEGTPVRQIEPQTLICPLDFSDDPRERKCPRGCNCHVR----TYDKALVINCHSG----- 653

  Fly  1045 VRVLDLAHNPLRRITLHDLASLRHLAELNILDVKVTNPQAFSKLRSLRKLHASSHANLGEIVARI 1109
                :|.|.| |...||                         |...|.:||..::..|....|..
  Fly   654 ----NLTHVP-RLPNLH-------------------------KNMQLMELHLENNTLLRLPSANT 688

  Fly  1110 PGLQQLRVHCLEPNIGQQLFAKLANNTKIRLLELYGSNVQTIAPDVFTGLSRSQRLQVKISHTRI 1174
            ||.:                       .:..|.|.|:|:.:|..|         :|...::|   
  Fly   689 PGYE-----------------------SVTSLHLAGNNLTSIDVD---------QLPTNLTH--- 718

  Fly  1175 SDLPPGIFYALREVPHLSIDISHNRINALAAD--SFYPNKSYWDAVGTRSIMGGLITSHNPLECE 1237
                              :|||.|.:..|.|.  .|......|     ||:.    .|.||..|:
  Fly   719 ------------------LDISWNHLQMLNATVLGFLNRTMKW-----RSVK----LSGNPWMCD 756

  Fly  1238 CGLVWFGHWLRRWLRESAQIKVIQKDDLKRMVQRARANTCHD---PTSGRHLPILEIFPED---L 1296
            |              .:..:.:..:|:.:|:..| ....|.:   ||....|...:|.|.:   .
  Fly   757 C--------------TAKPLLLFTQDNFERIGDR-NEMMCVNAEMPTRMVELSTNDICPAEKGVF 806

  Fly  1297 LCQASALSSSGQRIFLLSFAMAL 1319
            :..|..::.:|   .|..|..||
  Fly   807 IALAVVIALTG---LLAGFTAAL 826

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4168NP_609740.4 PRK15370 <69..>353 CDD:185268
leucine-rich repeat 99..118 CDD:275380
leucine-rich repeat 122..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..194 CDD:275380
leucine-rich repeat 195..214 CDD:275380
leucine-rich repeat 215..236 CDD:275380
leucine-rich repeat 266..287 CDD:275380
leucine-rich repeat 288..311 CDD:275380
leucine-rich repeat 312..338 CDD:275380
LRR <338..651 CDD:443914 64/276 (23%)
leucine-rich repeat 339..365 CDD:275380
leucine-rich repeat 366..388 CDD:275380
leucine-rich repeat 389..412 CDD:275380 1/1 (100%)
leucine-rich repeat 414..436 CDD:275380 8/36 (22%)
leucine-rich repeat 437..459 CDD:275380 5/35 (14%)
leucine-rich repeat 460..483 CDD:275380 5/22 (23%)
leucine-rich repeat 484..510 CDD:275380 8/25 (32%)
leucine-rich repeat 511..534 CDD:275380 6/22 (27%)
leucine-rich repeat 535..589 CDD:275380 5/56 (9%)
LRR 543..971 CDD:443914 104/457 (23%)
leucine-rich repeat 590..613 CDD:275380 7/24 (29%)
leucine-rich repeat 614..639 CDD:275380 11/24 (46%)
leucine-rich repeat 640..663 CDD:275380 7/24 (29%)
leucine-rich repeat 664..687 CDD:275380 6/22 (27%)
leucine-rich repeat 688..711 CDD:275380 3/22 (14%)
leucine-rich repeat 712..735 CDD:275380 8/22 (36%)
leucine-rich repeat 740..783 CDD:275380 7/44 (16%)
leucine-rich repeat 785..808 CDD:275380 0/22 (0%)
leucine-rich repeat 809..832 CDD:275380 6/22 (27%)
leucine-rich repeat 833..856 CDD:275380 9/33 (27%)
leucine-rich repeat 857..879 CDD:275380 5/26 (19%)
leucine-rich repeat 880..900 CDD:275380 1/19 (5%)
leucine-rich repeat 905..928 CDD:275380 9/25 (36%)
LRR 911..>1203 CDD:443914 66/317 (21%)
leucine-rich repeat 929..952 CDD:275380 5/27 (19%)
leucine-rich repeat 953..977 CDD:275380 10/29 (34%)
leucine-rich repeat 978..1020 CDD:275380 11/53 (21%)
leucine-rich repeat 1045..1068 CDD:275380 6/22 (27%)
leucine-rich repeat 1069..1090 CDD:275380 1/20 (5%)
leucine-rich repeat 1091..1114 CDD:275380 7/22 (32%)
leucine-rich repeat 1115..1161 CDD:275380 6/45 (13%)
leucine-rich repeat 1162..1190 CDD:275380 2/27 (7%)
PCC 1230..>1298 CDD:188093 14/73 (19%)
TlNP_001262995.1 LRR_8 174..233 CDD:404697 16/62 (26%)
leucine-rich repeat 176..198 CDD:275380 8/25 (32%)
leucine-rich repeat 199..222 CDD:275380 6/22 (27%)
LRR 222..576 CDD:443914 106/474 (22%)
leucine-rich repeat 223..270 CDD:275380 12/82 (15%)
leucine-rich repeat 271..294 CDD:275380 11/24 (46%)
leucine-rich repeat 295..320 CDD:275380 7/24 (29%)
leucine-rich repeat 321..343 CDD:275380 6/22 (27%)
leucine-rich repeat 344..367 CDD:275380 3/22 (14%)
leucine-rich repeat 368..391 CDD:275380 8/22 (36%)
leucine-rich repeat 392..415 CDD:275380 8/48 (17%)
leucine-rich repeat 416..439 CDD:275380 6/22 (27%)
leucine-rich repeat 440..474 CDD:275380 9/33 (27%)
leucine-rich repeat 475..498 CDD:275380 6/28 (21%)
leucine-rich repeat 499..520 CDD:275380 8/21 (38%)
leucine-rich repeat 523..552 CDD:275380 5/29 (17%)
LRRCT 561..619 CDD:214507 14/57 (25%)
LRRNT 631..667 CDD:214470 12/74 (16%)
PPP1R42 <660..752 CDD:455733 30/178 (17%)
leucine-rich repeat 664..693 CDD:275380 10/76 (13%)
leucine-rich repeat 694..715 CDD:275380 7/29 (24%)
leucine-rich repeat 716..737 CDD:275380 7/41 (17%)
LRRCT 751..800 CDD:214507 12/63 (19%)
TIR 858..996 CDD:214587
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.