DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4168 and CG5810

DIOPT Version :9

Sequence 1:NP_001285953.1 Gene:CG4168 / 34889 FlyBaseID:FBgn0028888 Length:1330 Species:Drosophila melanogaster
Sequence 2:NP_650952.2 Gene:CG5810 / 42513 FlyBaseID:FBgn0038866 Length:428 Species:Drosophila melanogaster


Alignment Length:432 Identity:108/432 - (25%)
Similarity:177/432 - (40%) Gaps:95/432 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   693 LSYNRLVNISHGAFTVLPNLAALDLMHNQLCSLSLKSFLYVSNTTTPLRLNVSHNHIASFYDELS 757
            |:|...:.|:..||....:        .:|..:::.|.....||.|.|:. .|.:.:|.|.:.::
  Fly     4 LNYLNYILIAVIAFATCES--------QKLEEIAIDSLDCRENTCTNLKY-PSASAVAYFSENVT 59

  Fly   758 SYMYIYQLDISHNHVTKSDSFTNLANTLR--FLNL--------AHNQLGSLQSHAFGDLEFLEIL 812
            .::..|:..:.|:        ::|||..|  ||||        ...:|..::|..|...:.|:.|
  Fly    60 KHLRKYETLVLHS--------SDLANLPRKIFLNLPQLVEFHVLECELQQIESVCFDGAKNLKRL 116

  Fly   813 NVAHNNLTSLRRRSFQGLNSLQELDLSHNQLDQLQVEQFSNLRKLRILRINSNRLRALPREVFMN 877
            |...|.|..|...:|:....|:||:||.|||:.|....|..|:.|:.:.:::|||..|.:.:|  
  Fly   117 NFGGNALRVLDSNTFELATQLEELNLSDNQLEDLPTTIFRPLKNLQKINLSNNRLITLSQHIF-- 179

  Fly   878 TRLEFLDIAENQLSVWPVPAFTDIGFTLRSIQMSHNNLEYLDASMFINS-QFLYDISLARNRITI 941
                      :||.            :|:||.:..|.|..|...:|.:. :.|.:.|...|::..
  Fly   180 ----------SQLG------------SLKSINVDSNQLVELPGELFRDQRKHLSEFSAQSNQLVR 222

  Fly   942 LPDNTF--------SFLNNLTNLDLSQ--NPLVTTN----------------------LREVFVH 974
            :|.|.|        ||...|..|.||.  |.|..||                      |.|:.:.
  Fly   223 IPFNIFREIDHLSLSFNPQLRRLHLSAKINELEATNCDLESVELDGRVIGVQLEANPKLHELKIS 287

  Fly   975 TPR-LRKLSLHHMGLYVLPPL----KLPLLSYLDVSGNYLQELSPLGSLRHLRHVNVSHNKLT-N 1033
            .|: |..|.|.:..||.|..|    ||..|...|:..  |.:|..:.|.:.|..::.:::.|| |
  Fly   288 QPQDLEHLYLANTNLYRLDFLSKASKLVDLDVTDIVN--LADLPKITSAKGLERLSFTYDNLTSN 350

  Fly  1034 ASCAAEHLPPSVRVLDLAHNPLRRITLHDLAS--LRHLAELN 1073
            ......|| ..:..|:::|...:.|.:.||..  ....||||
  Fly   351 HMDMLPHL-KDLNYLEISHEKGKEIFIKDLDEDFFVEEAELN 391

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4168NP_001285953.1 leucine-rich repeat 99..118 CDD:275380
LRR_8 121..181 CDD:290566
LRR_RI 122..350 CDD:238064
leucine-rich repeat 122..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..194 CDD:275380
leucine-rich repeat 195..214 CDD:275380
leucine-rich repeat 215..236 CDD:275380
LRR_8 265..322 CDD:290566
leucine-rich repeat 266..287 CDD:275380
leucine-rich repeat 288..311 CDD:275380
leucine-rich repeat 312..338 CDD:275380
LRR_RI 315..546 CDD:238064
leucine-rich repeat 339..365 CDD:275380
LRR_8 365..424 CDD:290566
leucine-rich repeat 366..388 CDD:275380
leucine-rich repeat 389..412 CDD:275380
LRR_8 413..470 CDD:290566
leucine-rich repeat 414..436 CDD:275380
leucine-rich repeat 437..459 CDD:275380
leucine-rich repeat 460..483 CDD:275380
LRR_8 482..545 CDD:290566
leucine-rich repeat 484..510 CDD:275380
leucine-rich repeat 511..534 CDD:275380
leucine-rich repeat 535..589 CDD:275380
LRR_RI 588..891 CDD:238064 52/207 (25%)
LRR_8 588..650 CDD:290566
leucine-rich repeat 590..613 CDD:275380
leucine-rich repeat 614..639 CDD:275380
LRR_8 638..698 CDD:290566 2/4 (50%)
leucine-rich repeat 640..663 CDD:275380
leucine-rich repeat 664..687 CDD:275380
LRR_8 688..749 CDD:290566 12/55 (22%)
leucine-rich repeat 688..711 CDD:275380 5/17 (29%)
leucine-rich repeat 712..735 CDD:275380 2/22 (9%)
leucine-rich repeat 740..783 CDD:275380 7/42 (17%)
LRR_8 784..843 CDD:290566 21/68 (31%)
leucine-rich repeat 785..808 CDD:275380 8/32 (25%)
leucine-rich repeat 809..832 CDD:275380 7/22 (32%)
LRR_RI <827..1053 CDD:238064 67/264 (25%)
LRR_8 832..890 CDD:290566 17/57 (30%)
leucine-rich repeat 833..856 CDD:275380 11/22 (50%)
leucine-rich repeat 857..879 CDD:275380 6/21 (29%)
leucine-rich repeat 880..900 CDD:275380 2/19 (11%)
LRR_8 904..963 CDD:290566 20/69 (29%)
leucine-rich repeat 905..928 CDD:275380 7/23 (30%)
leucine-rich repeat 929..952 CDD:275380 8/30 (27%)
leucine-rich repeat 953..977 CDD:275380 10/47 (21%)
leucine-rich repeat 978..1020 CDD:275380 14/45 (31%)
LRR_8 1019..1074 CDD:290566 15/58 (26%)
leucine-rich repeat 1045..1068 CDD:275380 5/24 (21%)
leucine-rich repeat 1069..1090 CDD:275380 4/5 (80%)
leucine-rich repeat 1091..1114 CDD:275380
leucine-rich repeat 1115..1161 CDD:275380
leucine-rich repeat 1162..1190 CDD:275380
CG5810NP_650952.2 leucine-rich repeat 65..88 CDD:275380 10/30 (33%)
LRR_8 87..147 CDD:290566 16/59 (27%)
leucine-rich repeat 89..112 CDD:275380 3/22 (14%)
leucine-rich repeat 113..136 CDD:275380 7/22 (32%)
LRR_8 135..195 CDD:290566 23/83 (28%)
LRR_4 135..175 CDD:289563 15/39 (38%)
leucine-rich repeat 137..160 CDD:275380 11/22 (50%)
leucine-rich repeat 161..184 CDD:275380 8/46 (17%)
leucine-rich repeat 185..209 CDD:275380 7/23 (30%)
leucine-rich repeat 210..231 CDD:275380 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45469445
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

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