DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4168 and Con

DIOPT Version :9

Sequence 1:NP_001285953.1 Gene:CG4168 / 34889 FlyBaseID:FBgn0028888 Length:1330 Species:Drosophila melanogaster
Sequence 2:NP_001246635.1 Gene:Con / 38590 FlyBaseID:FBgn0005775 Length:691 Species:Drosophila melanogaster


Alignment Length:647 Identity:134/647 - (20%)
Similarity:223/647 - (34%) Gaps:214/647 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   592 WL---GLDNNNLKQVSNESFAQMRELSYINLSFNQLKTLPRGLFQSDAHSHLVEIDLSYNGLERL 653
            |:   ||..|:..........::|||.::              .|::|.            |:.:
  Fly   136 WVFSEGLHQNDTTWTRFYQQKRLRELKFV--------------IQNNAR------------LDYI 174

  Fly   654 EAQTFHSLGDLQTLNLQSNRLRTIARHAFHNLEFLRYLDLSYNRLVNISHGAFTVLPNLAALDLM 718
            .......|.:|.::.::.:::..:..:||.||.||..:.|:.|.::.:...||.....|..|:|.
  Fly   175 PTMIIEPLKNLSSIVIEYSQVEIVKSYAFANLPFLERIILNNNHIMALDQDAFANHIRLRELNLE 239

  Fly   719 HNQLCSLSLKSFLYVSNTTTPL--RLNVSHNHIASFYDELSSYMYIYQLDISHNHVTKSDSFTNL 781
            |||:..:...:|     ...||  ||.:::|:|::.::.|                     |.::
  Fly   240 HNQIFEMDRYAF-----RNLPLCERLFLNNNNISTLHEGL---------------------FADM 278

  Fly   782 ANTLRFLNLAHNQLGSLQSHAFGDLEFLEILNVAHNNLTSLRRRSFQGLNSLQELDLSHNQLDQL 846
            |. |.||||||||:..|.|..|..|..|.:|.:..|||..:....|..|.||.||:|..|:::::
  Fly   279 AR-LTFLNLAHNQINVLTSEIFRGLGNLNVLKLTRNNLNFIGDTVFAELWSLSELELDDNRIERI 342

  Fly   847 QVEQFSNLRKLRILRINSNRLRALPREVFMNTRLEFLDIAENQLSVWPVPAFTDIGFTLRSIQMS 911
            .......|..|:.|.:.:|.|:.:...:...|                 ||       |.||.:.
  Fly   343 SERALDGLNTLKTLNLRNNLLKKIDNGLLRGT-----------------PA-------LLSINVQ 383

  Fly   912 HNNLEYLDASMFINSQFLYDISLARNRITILPDNTFSFLNNLTNLDLSQNPLV-TTNLREVFVHT 975
            .|.||.|   .|...|.:.|                :.:|:.:.|.:|.|..: ...|:.:|...
  Fly   384 ANKLETL---TFYTFQPIMD----------------NLVNSTSELLVSDNKFICDCRLQWIFELK 429

  Fly   976 PRLRKLSLH------HMGL------YVLPPLKLPLLSYLDVSGNYLQELSPLGS----------- 1017
            .|.|.|.|.      |..|      :.:.|:...:|..|::.|     .:.:||           
  Fly   430 NRTRHLQLRDSLEDLHCTLQEPKLSHFVDPVPPTILDVLNIGG-----FTAIGSNSASMGGVGNS 489

  Fly  1018 -------------------------LRHLRHV-----NVSHNKLTNASCAAEHL---------PP 1043
                                     ||..|..     ||..:|:.......|.:         |.
  Fly   490 VVGSSYSGLTMDDSRKHLGSRSRQALRGQRQFASSAENVVESKMRRRRKRQEEVKEKDLAAVAPA 554

  Fly  1044 SVRV---------------LDLAHNPLRRITLH-----------------DLASLRHLAELNILD 1076
            ..|.               |||..|    ::||                 |:....|.|..:.||
  Fly   555 HKRYDYYDDNNGGMSLGHGLDLDDN----LSLHKQGFYGAGSPVVGHNDVDVLMTSHSASGDALD 615

  Fly  1077 VKVTNPQAFSKLRSLRKLHASSHANLGEIVARIP---GLQQLRVHCLEPNIGQQLFAKLANN 1135
            :..|....:.||..|:......|..|.: ...:|   .|..:|     .|:||.:....||:
  Fly   616 ILTTKNAIYIKLFLLKPEMLPCHDELSD-PTELPLSRDLMDVR-----SNVGQDMSTAGANS 671

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4168NP_001285953.1 leucine-rich repeat 99..118 CDD:275380
LRR_8 121..181 CDD:290566
LRR_RI 122..350 CDD:238064
leucine-rich repeat 122..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..194 CDD:275380
leucine-rich repeat 195..214 CDD:275380
leucine-rich repeat 215..236 CDD:275380
LRR_8 265..322 CDD:290566
leucine-rich repeat 266..287 CDD:275380
leucine-rich repeat 288..311 CDD:275380
leucine-rich repeat 312..338 CDD:275380
LRR_RI 315..546 CDD:238064
leucine-rich repeat 339..365 CDD:275380
LRR_8 365..424 CDD:290566
leucine-rich repeat 366..388 CDD:275380
leucine-rich repeat 389..412 CDD:275380
LRR_8 413..470 CDD:290566
leucine-rich repeat 414..436 CDD:275380
leucine-rich repeat 437..459 CDD:275380
leucine-rich repeat 460..483 CDD:275380
LRR_8 482..545 CDD:290566
leucine-rich repeat 484..510 CDD:275380
leucine-rich repeat 511..534 CDD:275380
leucine-rich repeat 535..589 CDD:275380
LRR_RI 588..891 CDD:238064 70/303 (23%)
LRR_8 588..650 CDD:290566 9/60 (15%)
leucine-rich repeat 590..613 CDD:275380 4/23 (17%)
leucine-rich repeat 614..639 CDD:275380 3/24 (13%)
LRR_8 638..698 CDD:290566 11/59 (19%)
leucine-rich repeat 640..663 CDD:275380 2/22 (9%)
leucine-rich repeat 664..687 CDD:275380 5/22 (23%)
LRR_8 688..749 CDD:290566 17/62 (27%)
leucine-rich repeat 688..711 CDD:275380 5/22 (23%)
leucine-rich repeat 712..735 CDD:275380 7/22 (32%)
leucine-rich repeat 740..783 CDD:275380 7/44 (16%)
LRR_8 784..843 CDD:290566 26/58 (45%)
leucine-rich repeat 785..808 CDD:275380 13/22 (59%)
leucine-rich repeat 809..832 CDD:275380 7/22 (32%)
LRR_RI <827..1053 CDD:238064 56/303 (18%)
LRR_8 832..890 CDD:290566 12/57 (21%)
leucine-rich repeat 833..856 CDD:275380 6/22 (27%)
leucine-rich repeat 857..879 CDD:275380 4/21 (19%)
leucine-rich repeat 880..900 CDD:275380 2/19 (11%)
LRR_8 904..963 CDD:290566 14/58 (24%)
leucine-rich repeat 905..928 CDD:275380 8/22 (36%)
leucine-rich repeat 929..952 CDD:275380 1/22 (5%)
leucine-rich repeat 953..977 CDD:275380 5/24 (21%)
leucine-rich repeat 978..1020 CDD:275380 12/89 (13%)
LRR_8 1019..1074 CDD:290566 17/100 (17%)
leucine-rich repeat 1045..1068 CDD:275380 8/54 (15%)
leucine-rich repeat 1069..1090 CDD:275380 6/20 (30%)
leucine-rich repeat 1091..1114 CDD:275380 5/25 (20%)
leucine-rich repeat 1115..1161 CDD:275380 6/21 (29%)
leucine-rich repeat 1162..1190 CDD:275380
ConNP_001246635.1 LRR_RI <147..291 CDD:238064 42/196 (21%)
LRR_8 183..243 CDD:290566 16/59 (27%)
leucine-rich repeat 185..208 CDD:275380 5/22 (23%)
leucine-rich repeat 209..232 CDD:275380 5/22 (23%)
LRR_RI <225..416 CDD:238064 66/260 (25%)
LRR_8 232..291 CDD:290566 24/85 (28%)
leucine-rich repeat 233..256 CDD:275380 7/27 (26%)
leucine-rich repeat 257..280 CDD:275380 6/43 (14%)
leucine-rich repeat 281..304 CDD:275380 13/22 (59%)
LRR_8 304..363 CDD:290566 17/58 (29%)
leucine-rich repeat 305..328 CDD:275380 7/22 (32%)
leucine-rich repeat 329..352 CDD:275380 6/22 (27%)
LRR_8 352..416 CDD:290566 21/106 (20%)
leucine-rich repeat 353..376 CDD:275380 5/39 (13%)
LRRCT 414..>450 CDD:214507 9/35 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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