DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4168 and rdo

DIOPT Version :9

Sequence 1:NP_001285953.1 Gene:CG4168 / 34889 FlyBaseID:FBgn0028888 Length:1330 Species:Drosophila melanogaster
Sequence 2:NP_001286024.1 Gene:rdo / 35077 FlyBaseID:FBgn0243486 Length:757 Species:Drosophila melanogaster


Alignment Length:578 Identity:136/578 - (23%)
Similarity:236/578 - (40%) Gaps:145/578 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   664 LQTLNLQSNRLRTIARHAFHNLEFLRYLDLSYNRLVNISHGAFTVLPNLAALDLMHNQLCSLSLK 728
            |:.|.:..:.|..|...:|..|::||.||||.|.:.||:...|....||..|||..|::..::..
  Fly    84 LEILRITDSNLPAIGAESFWGLKYLRILDLSKNNITNITENNFRGQDNLLELDLSKNKVLRMASS 148

  Fly   729 SFLYVSNTTTPLRLNVSHNHIASFYDELSSYMYIYQLDISHNHVTKSDSFTNLANTLRFLNLAHN 793
            :|.::::..   |||::.|.|...              :..|..        :.:.|::|:|:.|
  Fly   149 TFRHLTDLR---RLNLADNSIVEL--------------VQRNFF--------MLSRLKYLDLSGN 188

  Fly   794 QLGSLQSHAFGDLEFLEILNVAHNNLTSLRRRSFQGLNSLQELDLSHNQLDQLQVEQFSNLRKLR 858
            .|..||...|.|:..|::|...:..|..:..:.:..|..|.||||..|:...|..::|.::::|.
  Fly   189 PLQDLQPDVFRDVPELKVLKCRNCQLKKINPQMYNLLPLLSELDLGRNEFKFLDKDEFRDVKRLT 253

  Fly   859 ILRINSNRLRALPREVF-MNTRLEFLDIAENQLSVWPVPAFTDIGFTLRSIQMSHNNLEYLDASM 922
            .:.::.|:|..:..::| |...|..||::.|:|:..|..:|..:           .||.:||   
  Fly   254 KVLLDGNQLSVVVDQLFRMQKSLNHLDLSYNRLAKVPNDSFLQL-----------TNLTFLD--- 304

  Fly   923 FINSQFLYDISLARNRITILPDNTFSFLNNLTNLDLSQNPLV-TTNLREVFVHTPRLRKLSLHHM 986
                       |:.|::..|...:...|:||..|::|.|.|: ...:||.|  .|.:....|...
  Fly   305 -----------LSYNKLVRLEPQSIRSLSNLLTLNISGNVLMDLREMRETF--EPLIYYFFLTCS 356

  Fly   987 GLYVLPPLKLPLLSYLDVSGNYLQELSPLGSLRHLRHVNVSHNKLTNASCAAEHLPPSVRVLDLA 1051
            .|:.   ..:|.|::|.::......:..|...:.||::|:|.|.|.|.         ::.|:|  
  Fly   357 KLFF---QLIPQLTHLAIADMGTMPVGLLHPFKQLRYLNISGNSLNNT---------ALEVID-- 407

  Fly  1052 HNPLRRITLHDLASLRHLAELNILDVKVTNPQAFSKLRSLRKLHASSHANLGEIVARIPGLQQLR 1116
              |.|              ||..||:            |..:||..|.    :.|.||.|::.:|
  Fly   408 --PCR--------------ELEFLDL------------SRNQLHGISE----DTVLRIQGIRNVR 440

  Fly  1117 VH-----CLEPNIGQQLFAKLANNTKIRLLELYGSNVQTIAPDVFTGLSRSQRLQVKISHTRISD 1176
            :.     |.|.::|     ||.|..:                          :||.|.....|..
  Fly   441 LDNNPLICDECHMG-----KLINVVR--------------------------QLQWKWDTYPICF 474

  Fly  1177 LPPGIFYALREVPHLSIDISHNRINAL------AADSFYPNKSYWDAVGTRSIMGGLI 1228
            ||..:..|  |:.:|.|:..|..:..:      ||.:.| |......:.|.:|:||:|
  Fly   475 LPKSLRGA--EINNLDINGLHTCLTFITDEEQNAASTSY-NFLEHGGLNTLAILGGII 529

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4168NP_001285953.1 leucine-rich repeat 99..118 CDD:275380
LRR_8 121..181 CDD:290566
LRR_RI 122..350 CDD:238064
leucine-rich repeat 122..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..194 CDD:275380
leucine-rich repeat 195..214 CDD:275380
leucine-rich repeat 215..236 CDD:275380
LRR_8 265..322 CDD:290566
leucine-rich repeat 266..287 CDD:275380
leucine-rich repeat 288..311 CDD:275380
leucine-rich repeat 312..338 CDD:275380
LRR_RI 315..546 CDD:238064
leucine-rich repeat 339..365 CDD:275380
LRR_8 365..424 CDD:290566
leucine-rich repeat 366..388 CDD:275380
leucine-rich repeat 389..412 CDD:275380
LRR_8 413..470 CDD:290566
leucine-rich repeat 414..436 CDD:275380
leucine-rich repeat 437..459 CDD:275380
leucine-rich repeat 460..483 CDD:275380
LRR_8 482..545 CDD:290566
leucine-rich repeat 484..510 CDD:275380
leucine-rich repeat 511..534 CDD:275380
leucine-rich repeat 535..589 CDD:275380
LRR_RI 588..891 CDD:238064 59/227 (26%)
LRR_8 588..650 CDD:290566
leucine-rich repeat 590..613 CDD:275380
leucine-rich repeat 614..639 CDD:275380
LRR_8 638..698 CDD:290566 13/33 (39%)
leucine-rich repeat 640..663 CDD:275380
leucine-rich repeat 664..687 CDD:275380 6/22 (27%)
LRR_8 688..749 CDD:290566 21/60 (35%)
leucine-rich repeat 688..711 CDD:275380 10/22 (45%)
leucine-rich repeat 712..735 CDD:275380 6/22 (27%)
leucine-rich repeat 740..783 CDD:275380 6/42 (14%)
LRR_8 784..843 CDD:290566 19/58 (33%)
leucine-rich repeat 785..808 CDD:275380 9/22 (41%)
leucine-rich repeat 809..832 CDD:275380 4/22 (18%)
LRR_RI <827..1053 CDD:238064 54/227 (24%)
LRR_8 832..890 CDD:290566 17/58 (29%)
leucine-rich repeat 833..856 CDD:275380 8/22 (36%)
leucine-rich repeat 857..879 CDD:275380 5/22 (23%)
leucine-rich repeat 880..900 CDD:275380 7/19 (37%)
LRR_8 904..963 CDD:290566 13/58 (22%)
leucine-rich repeat 905..928 CDD:275380 4/22 (18%)
leucine-rich repeat 929..952 CDD:275380 4/22 (18%)
leucine-rich repeat 953..977 CDD:275380 8/24 (33%)
leucine-rich repeat 978..1020 CDD:275380 6/41 (15%)
LRR_8 1019..1074 CDD:290566 13/54 (24%)
leucine-rich repeat 1045..1068 CDD:275380 4/22 (18%)
leucine-rich repeat 1069..1090 CDD:275380 4/20 (20%)
leucine-rich repeat 1091..1114 CDD:275380 7/22 (32%)
leucine-rich repeat 1115..1161 CDD:275380 7/50 (14%)
leucine-rich repeat 1162..1190 CDD:275380 8/27 (30%)
rdoNP_001286024.1 leucine-rich repeat 84..107 CDD:275380 6/22 (27%)
leucine-rich repeat 108..131 CDD:275380 10/22 (45%)
LRR_8 131..190 CDD:290566 17/83 (20%)
leucine-rich repeat 132..155 CDD:275380 6/22 (27%)
LRR_RI 151..422 CDD:238064 79/364 (22%)
leucine-rich repeat 156..179 CDD:275380 6/47 (13%)
LRR_8 178..262 CDD:290566 23/83 (28%)
leucine-rich repeat 180..203 CDD:275380 9/22 (41%)
leucine-rich repeat 204..251 CDD:275380 12/46 (26%)
leucine-rich repeat 252..275 CDD:275380 5/22 (23%)
LRR_8 274..334 CDD:290566 20/84 (24%)
leucine-rich repeat 276..299 CDD:275380 7/33 (21%)
LRR_4 298..342 CDD:289563 14/57 (25%)
leucine-rich repeat 300..323 CDD:275380 7/36 (19%)
leucine-rich repeat 388..411 CDD:275380 11/49 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45453639
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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