DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4168 and Gp5

DIOPT Version :9

Sequence 1:NP_001285953.1 Gene:CG4168 / 34889 FlyBaseID:FBgn0028888 Length:1330 Species:Drosophila melanogaster
Sequence 2:NP_032174.2 Gene:Gp5 / 14729 MGIID:1096363 Length:567 Species:Mus musculus


Alignment Length:500 Identity:147/500 - (29%)
Similarity:215/500 - (43%) Gaps:116/500 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   466 SGNNFSMIPVLGLKNYTQLSYLNMGYNSITDIPEGIFAVDSWGSNLQTILLRNNKITHLHLGSFA 530
            ||.:.:.|..|||.  |.|:::.            :|.:|..       :|||:        ||:
Mouse    36 SGGSVAHIAELGLP--TNLTHIL------------LFRMDQG-------ILRNH--------SFS 71

  Fly   531 GLEQIQEISLSFNDITIHHPLVFENV--SRTLKILELSFAVFPARSLESLDPLDALLPLSQLIWL 593
            |:..:|.:.||.:.|:...|..|.::  .:||::.....:..| |::     ||.::.|.||.  
Mouse    72 GMTVLQRLMLSDSHISAIDPGTFNDLVKLKTLRLTRNKISRLP-RAI-----LDKMVLLEQLF-- 128

  Fly   594 GLDNNNLKQVSNESFAQMRELSYINLSFNQLKTLPRGLFQSDAHSHLVEIDLSYNGLERLEAQTF 658
             ||:|.|:.:....|.|:|.|..:.|:.|||..||..||.|.....|  :|||.|.|..|.....
Mouse   129 -LDHNALRDLDQNLFQQLRNLQELGLNQNQLSFLPANLFSSLRELKL--LDLSRNNLTHLPKGLL 190

  Fly   659 HSLGDLQTLNLQSNRLRTIARHAFHNLEFLRYLDLSYNRLVNISHGAFTVLPNLAALDLMHNQLC 723
            .:...|:.|.|.||:|.::......||..|..|.|..|.|.:::.|||..|.||::|.|..|.|.
Mouse   191 GAQVKLEKLLLYSNQLTSVDSGLLSNLGALTELRLERNHLRSVAPGAFDRLGNLSSLTLSGNLLE 255

  Fly   724 SLSLKSFLYVSNTTTPLRLNVSHNHIASFYDELSSYMYIYQLDISHNHVTKSDSFTNLANTLRFL 788
            ||....||:||:.:   ||.:..|.:....|.|                     |..:|. ||.|
Mouse   256 SLPPALFLHVSSVS---RLTLFENPLEELPDVL---------------------FGEMAG-LREL 295

  Fly   789 NLAHNQLGSLQSHAFGDLEFLEILNVAHN-NLTSLRRRSFQGLNSLQELDLSHNQLDQLQVEQFS 852
            .|....|.:|.:.||.:|..|:.|.:..| .|::|.|..||||..|:.|.|..|.|.:|:.:...
Mouse   296 WLNGTHLSTLPAAAFRNLSGLQTLGLTRNPRLSALPRGVFQGLRELRVLALHTNALAELRDDALR 360

  Fly   853 NLRKLRILRINSNRLRALPREVFMNTRLEFLDIAENQLSVWPVPAFTDIGFTLRSIQMSHNNLEY 917
            .|..||.:.:..||||||||.:|.|            ||            :|.|:|:.||.|| 
Mouse   361 GLGHLRQVSLRHNRLRALPRTLFRN------------LS------------SLESVQLEHNQLE- 400

  Fly   918 LDASMFINSQFLYDISLARNRITILPDNTFSFLNNLTNLDLSQNP 962
                                   .||.:.|:.|..||.:.|..||
Mouse   401 -----------------------TLPGDVFAALPQLTQVLLGHNP 422

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4168NP_001285953.1 leucine-rich repeat 99..118 CDD:275380
LRR_8 121..181 CDD:290566
LRR_RI 122..350 CDD:238064
leucine-rich repeat 122..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..194 CDD:275380
leucine-rich repeat 195..214 CDD:275380
leucine-rich repeat 215..236 CDD:275380
LRR_8 265..322 CDD:290566
leucine-rich repeat 266..287 CDD:275380
leucine-rich repeat 288..311 CDD:275380
leucine-rich repeat 312..338 CDD:275380
LRR_RI 315..546 CDD:238064 19/79 (24%)
leucine-rich repeat 339..365 CDD:275380
LRR_8 365..424 CDD:290566
leucine-rich repeat 366..388 CDD:275380
leucine-rich repeat 389..412 CDD:275380
LRR_8 413..470 CDD:290566 2/3 (67%)
leucine-rich repeat 414..436 CDD:275380
leucine-rich repeat 437..459 CDD:275380
leucine-rich repeat 460..483 CDD:275380 6/16 (38%)
LRR_8 482..545 CDD:290566 13/62 (21%)
leucine-rich repeat 484..510 CDD:275380 3/25 (12%)
leucine-rich repeat 511..534 CDD:275380 6/22 (27%)
leucine-rich repeat 535..589 CDD:275380 13/55 (24%)
LRR_RI 588..891 CDD:238064 100/303 (33%)
LRR_8 588..650 CDD:290566 24/61 (39%)
leucine-rich repeat 590..613 CDD:275380 7/22 (32%)
leucine-rich repeat 614..639 CDD:275380 10/24 (42%)
LRR_8 638..698 CDD:290566 19/59 (32%)
leucine-rich repeat 640..663 CDD:275380 7/22 (32%)
leucine-rich repeat 664..687 CDD:275380 8/22 (36%)
LRR_8 688..749 CDD:290566 24/60 (40%)
leucine-rich repeat 688..711 CDD:275380 9/22 (41%)
leucine-rich repeat 712..735 CDD:275380 10/22 (45%)
leucine-rich repeat 740..783 CDD:275380 6/42 (14%)
LRR_8 784..843 CDD:290566 23/59 (39%)
leucine-rich repeat 785..808 CDD:275380 9/22 (41%)
leucine-rich repeat 809..832 CDD:275380 10/23 (43%)
LRR_RI <827..1053 CDD:238064 40/135 (30%)
LRR_8 832..890 CDD:290566 19/57 (33%)
leucine-rich repeat 833..856 CDD:275380 7/22 (32%)
leucine-rich repeat 857..879 CDD:275380 12/21 (57%)
leucine-rich repeat 880..900 CDD:275380 2/19 (11%)
LRR_8 904..963 CDD:290566 15/58 (26%)
leucine-rich repeat 905..928 CDD:275380 7/22 (32%)
leucine-rich repeat 929..952 CDD:275380 4/22 (18%)
leucine-rich repeat 953..977 CDD:275380 4/9 (44%)
leucine-rich repeat 978..1020 CDD:275380
LRR_8 1019..1074 CDD:290566
leucine-rich repeat 1045..1068 CDD:275380
leucine-rich repeat 1069..1090 CDD:275380
leucine-rich repeat 1091..1114 CDD:275380
leucine-rich repeat 1115..1161 CDD:275380
leucine-rich repeat 1162..1190 CDD:275380
Gp5NP_032174.2 LRR 1 75..96 6/20 (30%)
LRR_8 76..134 CDD:290566 18/66 (27%)
leucine-rich repeat 76..99 CDD:275380 6/22 (27%)
LRR 2 99..120 5/26 (19%)
leucine-rich repeat 100..123 CDD:275380 6/28 (21%)
LRR 3 123..144 8/23 (35%)
LRR_8 124..182 CDD:290566 25/62 (40%)
leucine-rich repeat 124..147 CDD:275380 9/25 (36%)
LRR_RI 126..402 CDD:238064 109/353 (31%)
LRR 4 147..168 9/20 (45%)
leucine-rich repeat 148..171 CDD:275380 10/22 (45%)
LRR 5 171..193 7/23 (30%)
leucine-rich repeat 172..195 CDD:275380 7/24 (29%)
LRR_8 195..254 CDD:290566 22/58 (38%)
LRR 6 195..216 6/20 (30%)
leucine-rich repeat 196..219 CDD:275380 8/22 (36%)
LRR 7 219..240 8/20 (40%)
leucine-rich repeat 220..243 CDD:275380 9/22 (41%)
LRR_8 243..302 CDD:290566 23/83 (28%)
LRR 8 243..264 9/20 (45%)
leucine-rich repeat 244..267 CDD:275380 10/22 (45%)
LRR 9 267..288 6/44 (14%)
leucine-rich repeat 268..291 CDD:275380 6/46 (13%)
LRR 10 291..312 8/21 (38%)
leucine-rich repeat 292..315 CDD:275380 9/22 (41%)
LRR_8 314..375 CDD:290566 20/60 (33%)
LRR 11 315..337 7/21 (33%)
leucine-rich repeat 316..338 CDD:275380 8/21 (38%)
LRR 12 340..361 6/20 (30%)
leucine-rich repeat 341..364 CDD:275380 7/22 (32%)
LRR_8 364..422 CDD:290566 28/105 (27%)
LRR 13 364..385 11/20 (55%)
leucine-rich repeat 365..388 CDD:275380 14/46 (30%)
LRR 14 388..409 10/44 (23%)
leucine-rich repeat 389..410 CDD:275380 10/44 (23%)
TPKR_C2 421..>454 CDD:301599 1/1 (100%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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