DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stc and NFXL2

DIOPT Version :9

Sequence 1:	NP_476599.1	Gene:	stc / 34888	FlyBaseID:	FBgn0001978	Length:	1106	Species:	Drosophila melanogaster
Sequence 2:	NP_196185.4	Gene:	NFXL2 / 830450	AraportID:	AT5G05660	Length:	883	Species:	Arabidopsis thaliana

Alignment Length:	953	Identity:	269/953 - (28%)
Similarity:	378/953 - (39%)	Gaps:	235/953 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   292 RSDRRRPQKQQRYDNHRSNKRRDDWN---RNRDRINGFPRAVDDLDTSNESAHPSPEKQSQLQQI 353
            :|..:.|.::|...:..|:...|..|   |:.|..|....|..|   .:.|:.||....:::|..
plant    15 KSPPQPPSQEQPISDSDSDSGSDSENHQHRHNDLSNSIFEAYLD---CHSSSSPSSIDLAKIQSF 76

  Fly   354 SPRRGPPLPPADNEKLSQREKLVRDIEQRRLECLVCVEAIKSHQPTWSC-RNCYHMLHLKCTITW 417
                   |..:.:..:|               ||:|:|.||...||||| .:|:.:.||.|..:|
plant    77 -------LASSSSGAVS---------------CLICLERIKRTDPTWSCTSSCFAVFHLFCIQSW 119

  Fly   418 A-----------------SSSKSEVGWRCPACQNVLQ--DLPRDYLCFCGKLKNPPVSRT-ELAH 462
            |                 :.::.|..|.||.|::..|  .:||.|||:|||.::||.... .|.|
plant   120 ARQCLDLQAARAVTRPSSNPTEPEAVWNCPKCRSSYQKSKIPRRYLCYCGKEEDPPADNPWILPH 184

  Fly   463 SCGEVCCR--IEGCSHACTLLCHPGPCPPCQANVVRSCGCGRSTKTMQCAMKEEVLCGEICDKLL 525
            ||||||.|  ...|.|.|.||||||||..|...|...|.||......:|..| :..||::|:::|
plant   185 SCGEVCERPLSNNCGHCCLLLCHPGPCASCPKLVKAKCFCGGVEDVRRCGHK-QFSCGDVCERVL 248

  Fly   526 NCGEHRCQAECHSGKCAACSEQVVQQCHCGKQERKVPCTRESQDKRTYSCKDSCGQPLPCGHHKC 590
            :|..|.|:..||.|:|..|.|:.|.:|.|||.:.:..|.     :|.:.|:.||...|.||.|.|
plant   249 DCNIHNCREICHDGECPPCRERAVYKCSCGKVKEEKDCC-----ERVFRCEASCENMLNCGKHVC 308

  Fly   591 KDSCHAGSCRPCKLSPEQITSCPCGKMPVPAGQRSSCLDPIPTCEGICSRTLRCGKPAHPHQCGS 655
            :..||||.|..|....::  ||||||.   ..|..||....|.|.|.|.:.|.||.    |:|..
plant   309 ERGCHAGECGLCPYQGKR--SCPCGKR---FYQGLSCDVVAPLCGGTCDKVLGCGY----HRCPE 364

  Fly   656 KCHLGQC-PPCPKQTGVKCRCGHMDQMIKCRQLCNRADDARCKRRCTKKRSCGKHKCNVECCIDI 719
            :||.|.| ..|.......||||...:.:.|.|      :..|:|:|.:.|.|.:|.|...||
plant   365 RCHRGPCLETCRIVVTKSCRCGVTKKQVPCHQ------ELACERKCQRVRDCARHACRRRCC--- 420

  Fly   720 DHDCPLPCN----RTLSCGKHKCDQPCHRGNCPPCYRSSFEELYCECGAEVIYPPVPCGTKK--- 777
            |.:|| ||:    :.|.|..|||..|||:|.|.||  .....:.|.||.  .:..|||||:.
plant   421 DGECP-PCSEICGKKLRCRNHKCQSPCHQGPCAPC--PIMVTISCACGE--THFEVPCGTETNQK 480

  Fly   778 ------------------------------PICKLPCSRIHPCDHPPQHNCHS------------ 800
                                          |.|:|.|...:||.|..:..||.
plant   481 PPRCRKLCHITPLCRHGQNQKPHKCHYGACPPCRLLCDEEYPCGHKCKLRCHGPRPPPNREFILK 545

  Fly   801 --------------GPTCPPCMIFTTKLCHGNH-ELRKTIPCS-QPNFSCGMACGKPLPCGGHKC 849
                          |..||.|.....:.|.|:| ...|.:.|| :..|:|...||.|||||.|.|
plant   546 PTKKMLHIQAESTPGSPCPRCPEPVWRPCVGHHLAAEKRMICSDRTQFACDNLCGNPLPCGNHYC 610

  Fly   850 IKPCHEGPCQSAG--------EICRQSCTKPR-PTCGHKCAAACHEGACPETPCKELVEVQCECG 905
            ...||....:|:.        |.|...|.|.| |.|.|.|...||...||  |||.||:..|.||
plant   611 SYFCHALDIRSSSLDKRSESCEKCDLRCQKERTPRCQHPCPRRCHPEDCP--PCKTLVKRSCHCG 673

  Fly   906 -----------------NRKQNRSCQELAREHSRIATIQLASSMAEMSRGNYMEL-SEILAPA-- 950
                             ::.:.|||:...  |.::.              |...| .||..|.
plant   674 AMVHAFECIYYNTMSEKDQMKARSCRGPC--HRKLP--------------NCTHLCPEICHPGQC 722

  Fly   951 ---KKSNKTLDCNDECRLLERN---RRLAAALSSGNSDTKQ---------------KCLTKYSEF 994
               :|..|.:....:|..|::.   :.:.||..:..||.|:               .|.:|....
plant   723 PLPEKCGKKVVVRCKCLTLKKEWVCQDVQAAHRATGSDPKEVPKNQFGVGLLPCDSNCKSKLQVA 787

  Fly   995 VRGFAKKNPALTKSVYETLTDLVKLA-KESKQRSRSHSFPTMNR------EKRQLVHELCEVFGI 1052
            .....::|   .|.:.|......|.| |..|:|.|........|      ..::::..:..|..:
plant   788 ESVLTQRN---VKEIEEKEEPSGKNASKRRKRRGRGQDIQETTRLQKLAVTTKRILMVVMLVAML 849

  Fly  1053 ESVSYDKEPNRNVVATAHKDRCWFPATSIMEVLARESGQRRVP 1095
            .:|||          ..:|...|. :..:.||..:....||.|
plant   850 AAVSY----------YGYKGLLWL-SDWMNEVEEQRQKSRRYP 881

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stc	NP_476599.1	NF-X1-zinc-finger	464..510	CDD:100116	22/47 (47%)
		NF-X1-zinc-finger	517..565	CDD:100116	19/47 (40%)
		NF-X1-zinc-finger	575..617	CDD:100116	19/41 (46%)
		NF-X1-zinc-finger	634..686	CDD:100116	18/52 (35%)
		NF-X1-zinc-finger	723..775	CDD:100116	22/55 (40%)
		NF-X1-zinc-finger	834..882	CDD:100116	22/56 (39%)
		NF-X1-zinc-finger	865..915	CDD:100116	23/67 (34%)
		R3H_NF-X1	996..1069	CDD:100072	14/79 (18%)
NFXL2	NP_196185.4	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1952
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D299100at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820