DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15269 and ZNF479

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001357058.1 Gene:ZNF479 / 90827 HGNCID:23258 Length:524 Species:Homo sapiens


Alignment Length:222 Identity:93/222 - (41%)
Similarity:120/222 - (54%) Gaps:5/222 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly   295 EISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECP 358
            |..|||..|.|.|..|.||..|::.|...: ..|.:|||.||...|...|..:|...|.:|  |.
Human   294 ERPYKCEECGKAFSVSSTLTDHKRIHTGEKPCRCEECGKAFSWSSNLTRHKRIHTREKPYA--CE 356

  Fly   359 ECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRK 423
            |||:.|:....|..|.:||...|.|.|..|.:.|.:..|..:|.|||||.:|:||.||||.||..
Human   357 ECGQAFSLSSNLMRHRRIHTGEKPYTCEECGQDFRRSSALTIHKRIHTGERPYKCEECGKVFSLS 421

  Fly   424 MLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNY 488
            ..|..|.|.|:||:||:|..|||:|:..|.:|.|.|:|:|.:|::|..|.|||.....|..|...
Human   422 STLTDHKRIHTGERPYKCEECGKAFSLSSTLTDHKRIHTGERPYTCEECGKAFNCSSTLMQHKRI 486

  Fly   489 HTGCKPYVCPHPNCNQAFTQSSNMRTH 515
            |||.|||.|  ..|.|||...|::..|
Human   487 HTGEKPYKC--EECEQAFKWHSSLAKH 511

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 8/19 (42%)
COG5048 <316..502 CDD:227381 77/186 (41%)
C2H2 Zn finger 327..347 CDD:275368 8/19 (42%)
zf-C2H2 356..377 CDD:278523 7/20 (35%)
C2H2 Zn finger 357..377 CDD:275368 7/19 (37%)
zf-H2C2_2 369..394 CDD:290200 9/24 (38%)
C2H2 Zn finger 385..405 CDD:275368 6/19 (32%)
zf-H2C2_2 397..422 CDD:290200 15/24 (63%)
C2H2 Zn finger 413..433 CDD:275368 10/19 (53%)
zf-H2C2_2 426..449 CDD:290200 12/22 (55%)
zf-C2H2 439..461 CDD:278523 10/21 (48%)
C2H2 Zn finger 441..461 CDD:275368 9/19 (47%)
zf-C2H2 467..489 CDD:278523 7/21 (33%)
C2H2 Zn finger 469..489 CDD:275368 7/19 (37%)
C2H2 Zn finger 497..515 CDD:275368 6/17 (35%)
ZNF479NP_001357058.1 KRAB 16..76 CDD:214630
COG5048 <170..372 CDD:227381 29/79 (37%)
C2H2 Zn finger 187..207 CDD:275368
C2H2 Zn finger 215..235 CDD:275368
C2H2 Zn finger 243..263 CDD:275368
C2H2 Zn finger 271..291 CDD:275368
C2H2 Zn finger 299..319 CDD:275368 8/19 (42%)
COG5048 <323..479 CDD:227381 66/157 (42%)
C2H2 Zn finger 327..347 CDD:275368 8/19 (42%)
C2H2 Zn finger 355..375 CDD:275368 7/19 (37%)
C2H2 Zn finger 383..403 CDD:275368 6/19 (32%)
C2H2 Zn finger 411..431 CDD:275368 10/19 (53%)
C2H2 Zn finger 439..459 CDD:275368 9/19 (47%)
C2H2 Zn finger 467..487 CDD:275368 7/19 (37%)
zf-H2C2_2 480..503 CDD:338759 12/24 (50%)
C2H2 Zn finger 495..515 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24384
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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