DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15269 and ZNF70

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_068735.1 Gene:ZNF70 / 7621 HGNCID:13140 Length:446 Species:Homo sapiens


Alignment Length:232 Identity:102/232 - (43%)
Similarity:135/232 - (58%) Gaps:10/232 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   295 EISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECP 358
            |..|:||.|.|.|..|..|..|:|.|...| |||.:|||.||:..:.:.|..:|.|.:.:  :|.
Human   193 EKPYECRECGKAFRQSSALTQHQKIHTGKRPYECRECGKDFSRSSSLRKHERIHTGERPY--QCK 255

  Fly   359 ECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRK 423
            ||||:||....||.|.|||..:|.:||..|.|:|..|.....|.|||||.||:||:||||.||:.
Human   256 ECGKSFNQSSGLSQHRKIHTLKKPHECDLCGKAFCHRSHLIRHQRIHTGKKPYKCDECGKAFSQS 320

  Fly   424 MLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNY 488
            ..|.:|.:||:|||||:|..|||:|:..|::..|.|:|:|.||:.|..|.|||.....|..|...
Human   321 SNLIEHRKTHTGEKPYKCQKCGKAFSQSSSLIEHQRIHTGEKPYECCQCGKAFCHSSALIQHQRI 385

  Fly   489 HTGCKPYVCPHPNCNQAFTQSS----NMRTHAKKCQY 521
            |||.|||.|   .|.:||...|    :.:||.::..|
Human   386 HTGKKPYTC---ECGKAFRHRSALIEHYKTHTREKPY 419

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 9/19 (47%)
COG5048 <316..502 CDD:227381 86/186 (46%)
C2H2 Zn finger 327..347 CDD:275368 7/19 (37%)
zf-C2H2 356..377 CDD:278523 11/20 (55%)
C2H2 Zn finger 357..377 CDD:275368 11/19 (58%)
zf-H2C2_2 369..394 CDD:290200 12/24 (50%)
C2H2 Zn finger 385..405 CDD:275368 7/19 (37%)
zf-H2C2_2 397..422 CDD:290200 15/24 (63%)
C2H2 Zn finger 413..433 CDD:275368 9/19 (47%)
zf-H2C2_2 426..449 CDD:290200 13/22 (59%)
zf-C2H2 439..461 CDD:278523 9/21 (43%)
C2H2 Zn finger 441..461 CDD:275368 8/19 (42%)
zf-C2H2 467..489 CDD:278523 7/21 (33%)
C2H2 Zn finger 469..489 CDD:275368 7/19 (37%)
C2H2 Zn finger 497..515 CDD:275368 5/21 (24%)
ZNF70NP_068735.1 C2H2 Zn finger 92..108 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..138
COG5048 138..442 CDD:227381 102/232 (44%)
C2H2 Zn finger 142..162 CDD:275368
C2H2 Zn finger 170..190 CDD:275368
C2H2 Zn finger 198..218 CDD:275368 9/19 (47%)
C2H2 Zn finger 226..246 CDD:275368 7/19 (37%)
C2H2 Zn finger 254..274 CDD:275368 11/19 (58%)
C2H2 Zn finger 282..302 CDD:275368 7/19 (37%)
C2H2 Zn finger 310..330 CDD:275368 9/19 (47%)
C2H2 Zn finger 338..358 CDD:275368 8/19 (42%)
C2H2 Zn finger 366..386 CDD:275368 7/19 (37%)
C2H2 Zn finger 394..413 CDD:275368 5/21 (24%)
C2H2 Zn finger 421..441 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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