DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15269 and Zfp788

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001347603.1	Gene:	Zfp788 / 67607	MGIID:	1914857	Length:	884	Species:	Mus musculus

Alignment Length:	276	Identity:	103/276 - (37%)
Similarity:	141/276 - (51%)	Gaps:	21/276 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 EEISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAEC 357
            ||..|||..|.|||.|..:||:|.:.|...: |||..|||.|....::..|..||.|.|.:  ||
Mouse   290 EEKPYKCHYCNKVFICQGSLQSHIRVHTGEKPYECKQCGKAFRVNSSFWRHKKVHTGEKPY--EC 352

  Fly   358 PECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSR 422
            .:|||:|.....|.:|.:.|...|.|.|..|.|:|....:..:|.|.|||.||::|.:||:.|..
Mouse   353 KQCGKSFIYPSLLQTHERTHSAEKPYSCKQCGKAFKSHSSLRVHERNHTGKKPYECKQCGRSFIY 417

  Fly   423 KMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLN 487
            ..||:.|.|||||.|||.|..|||:|...|::.:|.|.|:|.||:.|..|.|:|..::.||.|..
Mouse   418 PCLLQIHERTHSGVKPYGCKQCGKAFRRLSDLRVHERTHTGEKPYECKQCAKSFINRYLLKMHQK 482

  Fly   488 YHTGCKPYVCPHPNCNQAFTQSSNMRTH-----------AKKCQYRPLDGLTVTSSALPVPGKQQ 541
            .|||.|||.|  ..|::||...|.::.|           .|:|     |...:..|.|.:..:..
Mouse   483 SHTGEKPYKC--KICSKAFVYPSLLKLHERSHTGEKPYPCKQC-----DKAFIFPSLLKLHERTH 540

  Fly   542 TGPPPTLAMAMAQTFQ 557
            ||..|.......:.|:
Mouse   541 TGEKPYACKQCGEAFK 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	9/19 (47%)
		COG5048	<316..502	CDD:227381	77/186 (41%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		zf-C2H2	356..377	CDD:278523	8/20 (40%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		zf-H2C2_2	369..394	CDD:290200	9/24 (38%)
		C2H2 Zn finger	385..405	CDD:275368	6/19 (32%)
		zf-H2C2_2	397..422	CDD:290200	11/24 (46%)
		C2H2 Zn finger	413..433	CDD:275368	8/19 (42%)
		zf-H2C2_2	426..449	CDD:290200	14/22 (64%)
		zf-C2H2	439..461	CDD:278523	9/21 (43%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		zf-C2H2	467..489	CDD:278523	7/21 (33%)
		C2H2 Zn finger	469..489	CDD:275368	7/19 (37%)
		C2H2 Zn finger	497..515	CDD:275368	5/17 (29%)
Zfp788	NP_001347603.1	KRAB	23..64	CDD:307490
		C2H2 Zn finger	240..260	CDD:275368
		C2H2 Zn finger	268..288	CDD:275368
		C2H2 Zn finger	296..316	CDD:275368	9/19 (47%)
		zf-H2C2_2	308..332	CDD:316026	10/23 (43%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		zf-H2C2_2	336..361	CDD:316026	11/26 (42%)
		C2H2 Zn finger	352..372	CDD:275368	7/19 (37%)
		C2H2 Zn finger	380..400	CDD:275368	6/19 (32%)
		C2H2 Zn finger	408..428	CDD:275368	8/19 (42%)
		C2H2 Zn finger	436..456	CDD:275368	8/19 (42%)
		C2H2 Zn finger	464..484	CDD:275368	7/19 (37%)
		COG5048	488..883	CDD:227381	18/76 (24%)
		C2H2 Zn finger	492..512	CDD:275368	6/21 (29%)
		C2H2 Zn finger	520..540	CDD:275368	5/24 (21%)
		C2H2 Zn finger	548..568	CDD:275368	1/9 (11%)
		C2H2 Zn finger	576..596	CDD:275368
		C2H2 Zn finger	604..624	CDD:275368
		C2H2 Zn finger	632..652	CDD:275368
		C2H2 Zn finger	660..680	CDD:275368
		C2H2 Zn finger	688..708	CDD:275368
		C2H2 Zn finger	716..736	CDD:275368
		C2H2 Zn finger	744..764	CDD:275368
		C2H2 Zn finger	772..792	CDD:275368
		C2H2 Zn finger	800..820	CDD:275368
		C2H2 Zn finger	828..848	CDD:275368
		C2H2 Zn finger	856..876	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910