DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15269 and ZNF667

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001308285.1 Gene:ZNF667 / 63934 HGNCID:28854 Length:610 Species:Homo sapiens


Alignment Length:227 Identity:92/227 - (40%)
Similarity:134/227 - (59%) Gaps:10/227 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   298 YKCRICEKVFGCSETLQAHEKTH--KSPRYECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPEC 360
            |:|..||||.....:|..|:|.|  |...:||.:|||.||...|.|.|.::|...|.|  :|.:|
Human   386 YRCNKCEKVCNRHSSLIQHQKVHTKKKKLFECKECGKMFSGTANLKIHQNIHSEEKPF--KCNKC 448

  Fly   361 GKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKML 425
            .|.|..:.:|..|.:||...|.|:|..|.|:|:.|::...|.||||..:|::|::|||.||:...
Human   449 SKVFGRQSFLIEHQRIHTGEKPYQCEECGKAFSHRISLTRHKRIHTEDRPYECDQCGKAFSQSAH 513

  Fly   426 LKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHT 490
            |.||.|.|:|||||.|..|||:|:.|:::.||.|.|:|.||:.|..|.|||:....|..|...|:
Human   514 LAQHERIHTGEKPYTCKTCGKAFSQRTSLILHERSHTGEKPYECNECGKAFSSGSDLIRHQRSHS 578

  Fly   491 GCKPYVCPHPNCNQAFTQSSNM----RTHAKK 518
            ..|||.|  ..|.:|:::||::    .||:::
Human   579 SEKPYEC--SKCGKAYSRSSSLIRHQNTHSEE 608

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 8/19 (42%)
COG5048 <316..502 CDD:227381 79/187 (42%)
C2H2 Zn finger 327..347 CDD:275368 9/19 (47%)
zf-C2H2 356..377 CDD:278523 6/20 (30%)
C2H2 Zn finger 357..377 CDD:275368 6/19 (32%)
zf-H2C2_2 369..394 CDD:290200 10/24 (42%)
C2H2 Zn finger 385..405 CDD:275368 7/19 (37%)
zf-H2C2_2 397..422 CDD:290200 11/24 (46%)
C2H2 Zn finger 413..433 CDD:275368 10/19 (53%)
zf-H2C2_2 426..449 CDD:290200 14/22 (64%)
zf-C2H2 439..461 CDD:278523 10/21 (48%)
C2H2 Zn finger 441..461 CDD:275368 9/19 (47%)
zf-C2H2 467..489 CDD:278523 7/21 (33%)
C2H2 Zn finger 469..489 CDD:275368 7/19 (37%)
C2H2 Zn finger 497..515 CDD:275368 5/21 (24%)
ZNF667NP_001308285.1 KRAB 15..74 CDD:214630
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 119..139
COG5048 141..601 CDD:227381 90/218 (41%)
C2H2 Zn finger 146..166 CDD:275368
C2H2 Zn finger 174..194 CDD:275368
C2H2 Zn finger 202..222 CDD:275368
C2H2 Zn finger 255..275 CDD:275368
C2H2 Zn finger 284..303 CDD:275368
C2H2 Zn finger 332..352 CDD:275368
C2H2 Zn finger 360..380 CDD:275368
C2H2 Zn finger 388..408 CDD:275368 8/19 (42%)
C2H2 Zn finger 417..437 CDD:275368 9/19 (47%)
C2H2 Zn finger 445..465 CDD:275368 6/19 (32%)
C2H2 Zn finger 473..493 CDD:275368 7/19 (37%)
C2H2 Zn finger 501..521 CDD:275368 10/19 (53%)
C2H2 Zn finger 529..549 CDD:275368 9/19 (47%)
C2H2 Zn finger 557..577 CDD:275368 7/19 (37%)
C2H2 Zn finger 585..605 CDD:275368 5/21 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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