DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15269 and Klf6

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_113830.2 Gene:Klf6 / 58954 RGDID:62389 Length:317 Species:Rattus norvegicus


Alignment Length:396 Identity:87/396 - (21%)
Similarity:128/396 - (32%) Gaps:153/396 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly   159 GSVPPPPPLQQQQQPLIRTKSTACTRPDCPECL-------------------------------- 191
            |:|..|.|          .:|..|. ||..:||                                
  Rat     9 GTVSAPTP----------DRSPPCF-PDSGDCLFQPDMDVLPMCSIFQELQIVHETGYFSALPSL 62

  Fly   192 -DYYQR--LQTGGYKQTAPLISPAAS-------------------------SVSSSTGSIRPVRD 228
             :|:|:  |:...|.|:.|....|:.                         .:|||.    |...
  Rat    63 EEYWQQTCLELERYLQSEPCYVSASEIKFDNQEDLWTKIILARERKEESELKISSSP----PEDS 123

  Fly   229 LIMSATGGAASTNISLTTVTNLSLNSVQATAVGMMPKMTGGLITTAVGS---NSGAIGGIGGYNA 290
            ||.|.......||...:.|::.|.:|.:.    :.|  |....:..:|.   |||.:........
  Rat   124 LISSGFNYNLETNSLNSDVSSESSDSSEE----LSP--TTKFTSDPIGEVLVNSGNLSSSVISTP 182

  Fly   291 TSAEEISYKCRICEKVFGCSETLQAHEKTHKSPRYECADCGKGFSQLRNYKYHLSVHRGTKEFAA 355
            .|:.|::   |...:::||...             :....||             |..||.    
  Rat   183 PSSPEVN---RESSQLWGCGPG-------------DLPSPGK-------------VRSGTS---- 214

  Fly   356 ECPECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRF 420
                 ||: .|||  |........|:.:.|.:                          |.|.|.:
  Rat   215 -----GKS-GDKG--SGDASPDGRRRVHRCHF--------------------------NGCRKVY 245

  Fly   421 SRKMLLKQHMRTHSGEKPYQCS--VCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLK 483
            ::...||.|.|||:|||||:||  .|...||....:|.|.|.|:|.|||.|..|.:.|::..||.
  Rat   246 TKSSHLKAHQRTHTGEKPYRCSWEGCEWRFARSDELTRHFRKHTGAKPFKCSHCDRCFSRSDHLA 310

  Fly   484 THLNYH 489
            .|:..|
  Rat   311 LHMKRH 316

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 3/19 (16%)
COG5048 <316..502 CDD:227381 47/176 (27%)
C2H2 Zn finger 327..347 CDD:275368 2/19 (11%)
zf-C2H2 356..377 CDD:278523 6/20 (30%)
C2H2 Zn finger 357..377 CDD:275368 6/19 (32%)
zf-H2C2_2 369..394 CDD:290200 3/24 (13%)
C2H2 Zn finger 385..405 CDD:275368 1/19 (5%)
zf-H2C2_2 397..422 CDD:290200 3/24 (13%)
C2H2 Zn finger 413..433 CDD:275368 7/19 (37%)
zf-H2C2_2 426..449 CDD:290200 14/24 (58%)
zf-C2H2 439..461 CDD:278523 9/23 (39%)
C2H2 Zn finger 441..461 CDD:275368 8/21 (38%)
zf-C2H2 467..489 CDD:278523 7/21 (33%)
C2H2 Zn finger 469..489 CDD:275368 6/19 (32%)
C2H2 Zn finger 497..515 CDD:275368
Klf6NP_113830.2 COG5048 211..>299 CDD:227381 38/125 (30%)
zf-C2H2 234..258 CDD:278523 8/49 (16%)
C2H2 Zn finger 239..258 CDD:275368 7/18 (39%)
zf-H2C2_2 250..>266 CDD:290200 11/15 (73%)
C2H2 Zn finger 266..288 CDD:275368 8/21 (38%)
zf-H2C2_2 280..305 CDD:290200 11/24 (46%)
C2H2 Zn finger 296..316 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.