DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and zbtb41

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_001922702.4	Gene:	zbtb41 / 573743	ZFINID:	ZDB-GENE-130530-649	Length:	889	Species:	Danio rerio

Alignment Length:	572	Identity:	129/572 - (22%)
Similarity:	192/572 - (33%)	Gaps:	205/572 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 AAAAAAGLSTPPTSPYQTHQHQQHLPNQQKRF---FAPYVINGSVPPPPPLQQQQQPLIRTKSTA 181
            |..:.|...|.|...:...:|.|........|   .||.||:.:               ..||..
Zfish   311 ACVSEAQKETEPAFSHALEEHNQKTEVSSHIFPEGLAPVVIHST---------------NKKSLK 360

  Fly   182 CTRPDCPECLDYYQRLQTGGYKQTAPLISPAASSVSSSTGSIRPVR-DLIMSATGGAASTNISLT 245
            |  |.|.:..|     :.|.|:          |.....||. :|.: |:.:..          .:
Zfish   361 C--PKCDKIFD-----RKGKYE----------SHTRVHTGE-KPFQCDICLQC----------YS 397

  Fly   246 TVTNLSLNSVQATAVGMMPKMTGGLITTAVGSNSGAIGGIGGYNATSAEEISYKCRICEKVFGCS 310
            |.:||:::..:                    .:||          |..:...:||..|.|:....
Zfish   398 TKSNLTVHKKK--------------------HDSG----------TPVQRKEHKCPFCNKLHASK 432

  Fly   311 ETLQAHEK-------------THKSPRYECADCGKGFSQLRNYKYHLSVHRGTKEFAA------- 355
            :||..|.|             ..||..::|..|.|.||:..:.:.|:.:|...|.|..
Zfish   433 KTLSRHVKRFHPDHLQEFLTQKKKSEVWKCDICHKSFSRRPHLEEHMILHSQDKPFKCAYCDDYF 497

  Fly   356 ------------------ECPECGKTFNDKGYLSSHLK-IHRNRKEYECPYCPKSFNQRVAFNMH 401
                              .|..||:.|||.|....|:: .|..::::.|..|.||..:|.....|
Zfish   498 KSRFARLKHQEKFHLGPFPCDICGRQFNDTGNRKRHIECTHGGKRKWTCFLCGKSVRERTTLREH 562

  Fly   402 VRIHTGVKPH----------------------------KCNECGKRFSRKMLLKQHMRTHSGEKP 438
            :|||:|.|||                            :|.||||.|.|...||:|.:.|:|||.
Zfish   563 LRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHEDKRYECEECGKTFIRHDHLKKHKKIHTGEKA 627

  Fly   439 YQCSVCGKSF--AD-----------------------------------RSNMTLHHRLHSGIKP 466
            :||..|||.|  ||                                   ::|:..|.|.|||.||
Zfish   628 HQCEECGKCFRRADHLTVHYKSIHLGEKIWQRYKAVVHQCQVCKKEFRGKTNLMSHFRTHSGEKP 692

  Fly   467 FSCPLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTHAKKC-QYRPLDGLTVT 530
            ..|.:|.:.|:.|..|..|:..|:..:|:.|||  |:..|.:...::.|.... ..|.||
Zfish   693 HKCVICNQTFSIKKTLTKHMVIHSDVRPFNCPH--CSATFKRKDKLKYHVDHVHSVRLLD----- 750

  Fly   531 SSALPVPGKQQTGPPPTLAMAMAQTFQMPPPPGVLTPGSGPSQPPSQQTLLS 582
                     ||...|.:.|..:..       |.:....|.|.|..|:..|.|
Zfish   751 ---------QQQNQPASPANKLID-------PSLSNKNSKPCQNASKTVLQS 786

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	7/32 (22%)
		COG5048	<316..502	CDD:227381	76/289 (26%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		zf-C2H2	356..377	CDD:278523	8/21 (38%)
		C2H2 Zn finger	357..377	CDD:275368	8/20 (40%)
		zf-H2C2_2	369..394	CDD:290200	6/25 (24%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		zf-H2C2_2	397..422	CDD:290200	14/52 (27%)
		C2H2 Zn finger	413..433	CDD:275368	10/19 (53%)
		zf-H2C2_2	426..449	CDD:290200	13/24 (54%)
		zf-C2H2	439..461	CDD:278523	11/58 (19%)
		C2H2 Zn finger	441..461	CDD:275368	10/56 (18%)
		zf-C2H2	467..489	CDD:278523	6/21 (29%)
		C2H2 Zn finger	469..489	CDD:275368	6/19 (32%)
		C2H2 Zn finger	497..515	CDD:275368	5/17 (29%)
zbtb41	XP_001922702.4	BTB	50..149	CDD:279045
		BTB	62..145	CDD:197585
		C2H2 Zn finger	361..381	CDD:275368	7/36 (19%)
		C2H2 Zn finger	389..409	CDD:275368	4/49 (8%)
		C2H2 Zn finger	422..440	CDD:275368	6/17 (35%)
		COG5048	458..774	CDD:227381	83/338 (25%)
		C2H2 Zn finger	462..482	CDD:275368	6/19 (32%)
		C2H2 Zn finger	490..507	CDD:275368	0/16 (0%)
		C2H2 Zn finger	517..538	CDD:275368	8/20 (40%)
		C2H2 Zn finger	546..566	CDD:275368	7/19 (37%)
		zf-H2C2_2	559..583	CDD:290200	8/23 (35%)
		C2H2 Zn finger	574..594	CDD:275368	0/19 (0%)
		zf-C2H2	600..622	CDD:278523	10/21 (48%)
		C2H2 Zn finger	602..622	CDD:275368	10/19 (53%)
		zf-H2C2_2	614..639	CDD:290200	13/24 (54%)
		C2H2 Zn finger	630..651	CDD:275368	7/20 (35%)
		C2H2 Zn finger	667..684	CDD:275368	1/16 (6%)
		zf-H2C2_2	679..703	CDD:290200	10/23 (43%)
		C2H2 Zn finger	695..715	CDD:275368	6/19 (32%)
		C2H2 Zn finger	723..740	CDD:275368	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910