DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and Zfp773-ps1

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_017445439.1	Gene:	Zfp773-ps1 / 502292	RGDID:	1563793	Length:	424	Species:	Rattus norvegicus

Alignment Length:	418	Identity:	121/418 - (28%)
Similarity:	191/418 - (45%)	Gaps:	45/418 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 AAAAAGLSTPPTSPYQTHQHQQHLPNQQKRFFAPYVI--------NGSVPPPPPLQQQQQ----- 172
            |.|..|::....:.|...:..:.|.:.|:|.:...::        :|.||....:.|.:.
  Rat    17 AQAQGGVAFHDVAIYFLREEWRLLDDSQRRLYHHVMMEVFVLMSSSGLVPSGTDITQLESSGDRF 81

  Fly   173 -PLIR--TKSTACTRPDCPECLDYYQRLQTGGYKQTAPLISPAASSVSSSTGSIRPVRDLIMSAT 234
             |.:|  |......:..|.:.|...:|    |...|   :.| ...:||:...::
  Rat    82 IPALRFLTPRVEPAKIPCEQTLSTTER----GLNVT---MLP-QQELSSAENHLQ---------- 128

  Fly   235 GGAASTNISLT--TVTNLSLNSVQATAVGMMPKMTGGLI-TTAVGSNSGAIGGIGGYNATSAEEI 296
              .|...:|:|  ..:::|..::|:|...|..:...||: ..|..|:.|.........||.:|:.
  Rat   129 --RAEHRLSVTKRNRSDISEKTLQSTDNTMDSRTLSGLLGHHATHSDGGQPRSTKKGKATHSEKR 191

  Fly   297 SYK-CRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPE 359
            :|| |..|.|.|.|...|..|.:.|...: ::|::|.|.|.|..:...||.||.|.|.|  .|.:
  Rat   192 NYKCCSYCGKSFNCRSLLIRHRRIHTGEKPFKCSECEKSFIQKADLNQHLKVHTGEKPF--RCSK 254

  Fly   360 CGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKM 424
            |||.|.....|..|.::|...|.|:|..|.:|:..|.:...|..:|||.||:||:||||.|..|.
  Rat   255 CGKKFKHSRSLVGHQRLHTGEKPYKCNQCGESYVNRSSLIRHNLVHTGEKPYKCSECGKLFKEKS 319

  Fly   425 LLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYH 489
            .|..|.|.|:||:|::||.|.|||...|::..|.::||..|||.|.:|.:.||.::.|..|..:|
  Rat   320 SLVYHARVHTGERPFECSQCKKSFKKNSHLVKHRKVHSRGKPFKCNVCGRFFTMRYILVKHQRFH 384

  Fly   490 TGCKPYVCPHPNCNQAFTQSSNMRTHAK 517
            |..|.:.|  ..|.:.|...:.:..|.|
  Rat   385 TAEKHHEC--KECGKVFCYRTGLSRHRK 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	7/19 (37%)
		COG5048	<316..502	CDD:227381	72/186 (39%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		zf-C2H2	356..377	CDD:278523	7/20 (35%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
		zf-H2C2_2	369..394	CDD:290200	8/24 (33%)
		C2H2 Zn finger	385..405	CDD:275368	5/19 (26%)
		zf-H2C2_2	397..422	CDD:290200	13/24 (54%)
		C2H2 Zn finger	413..433	CDD:275368	10/19 (53%)
		zf-H2C2_2	426..449	CDD:290200	12/22 (55%)
		zf-C2H2	439..461	CDD:278523	8/21 (38%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		zf-C2H2	467..489	CDD:278523	7/21 (33%)
		C2H2 Zn finger	469..489	CDD:275368	6/19 (32%)
		C2H2 Zn finger	497..515	CDD:275368	3/17 (18%)
Zfp773-ps1	XP_017445439.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24384
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010