DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15269 and CG6689

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_650051.1 Gene:CG6689 / 41345 FlyBaseID:FBgn0037877 Length:613 Species:Drosophila melanogaster


Alignment Length:342 Identity:86/342 - (25%)
Similarity:131/342 - (38%) Gaps:82/342 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   171 QQPLIRTKSTACTRPDCPECLDYYQRLQTGGYKQTAPLIS-PAASSVSSSTGSIRPVRDLIMSAT 234
            |.||    |.|.......|.||.|...:....::.||:.| |.|.  ..:.|..:|.|       
  Fly   309 QDPL----SVALGAKIFKELLDQYTGKEKARLRKGAPIASKPKAK--EKAAGEQKPKR------- 360

  Fly   235 GGAASTNISLTTVTNLSLNSVQATAVGMMPKMTGGLITTAVGSNSGAIGGIGGYNATSAEEISYK 299
                    |....|....|.::...:...|.                               ::.
  Fly   361 --------SANPKTKEERNLIRRAQLRAKPP-------------------------------NFV 386

  Fly   300 CRICEKVFGCSETLQAHEKTH-KSPRYECADCGKGF--SQLRNYKYHLSV-HRGTKEFAAECPEC 360
            |..|.:.|..|..|:.|...| ::..|:|.:|.|.|  :.:||  .|:.: |||...||  |..|
  Fly   387 CDQCGQAFRMSHNLRIHMLRHTRTKNYQCTECPKTFYDAYMRN--MHIRIRHRGETPFA--CGFC 447

  Fly   361 GKTFNDKGYLSSH-LKIH-------------------RNRKEYECPYCPKSFNQRVAFNMHVRIH 405
            .:||...|....| .::|                   |....|:|..|.|.:..:.|...|::.|
  Fly   448 SETFAYPGARQKHESEVHNAAPRLIVKRINPKPMPKPRESVRYQCKLCQKHYASKYALGWHIKSH 512

  Fly   406 TGVKPHKCNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCP 470
            |....:||..|.|.:|....||:|..||. ::|.||.||.|.|..|:.:..|..:|:|.:|:.|.
  Fly   513 TDANAYKCQRCSKSYSDPNKLKRHEMTHE-KRPLQCDVCLKGFYQRTRLREHELIHTGERPYWCE 576

  Fly   471 LCPKAFTKKHHLKTHLN 487
            :|...|..|:::|:|.|
  Fly   577 VCNVNFRYKYNMKSHAN 593

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 6/19 (32%)
COG5048 <316..502 CDD:227381 60/196 (31%)
C2H2 Zn finger 327..347 CDD:275368 7/22 (32%)
zf-C2H2 356..377 CDD:278523 6/21 (29%)
C2H2 Zn finger 357..377 CDD:275368 6/20 (30%)
zf-H2C2_2 369..394 CDD:290200 7/44 (16%)
C2H2 Zn finger 385..405 CDD:275368 5/19 (26%)
zf-H2C2_2 397..422 CDD:290200 8/24 (33%)
C2H2 Zn finger 413..433 CDD:275368 7/19 (37%)
zf-H2C2_2 426..449 CDD:290200 11/22 (50%)
zf-C2H2 439..461 CDD:278523 8/21 (38%)
C2H2 Zn finger 441..461 CDD:275368 7/19 (37%)
zf-C2H2 467..489 CDD:278523 7/21 (33%)
C2H2 Zn finger 469..489 CDD:275368 7/19 (37%)
C2H2 Zn finger 497..515 CDD:275368
CG6689NP_650051.1 THAP 2..96 CDD:283206
zf-AD 167..240 CDD:214871
zf-C2H2 385..407 CDD:278523 6/21 (29%)
C2H2 Zn finger 387..407 CDD:275368 6/19 (32%)
zf-H2C2_2 399..422 CDD:290200 7/22 (32%)
C2H2 Zn finger 415..436 CDD:275368 7/22 (32%)
C2H2 Zn finger 444..460 CDD:275368 5/15 (33%)
C2H2 Zn finger 492..512 CDD:275368 5/19 (26%)
C2H2 Zn finger 520..540 CDD:275368 7/19 (37%)
C2H2 Zn finger 547..567 CDD:275368 7/19 (37%)
zf-met 574..597 CDD:289631 7/20 (35%)
C2H2 Zn finger 575..591 CDD:275368 5/15 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45457853
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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