DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and Zif

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001189188.1	Gene:	Zif / 40795	FlyBaseID:	FBgn0037446	Length:	388	Species:	Drosophila melanogaster

Alignment Length:	180	Identity:	56/180 - (31%)
Similarity:	88/180 - (48%)	Gaps:	7/180 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   313 LQAHEKTHKSPRYECA--DCGKGFSQLRNYKYH-----LSVHRGTKEFAAECPECGKTFNDKGYL 370
            |::.::..::|..:.|  :..|...:.|..:..     |:...||::....|..||..:..:|.:
  Fly   174 LESEKQYEETPSQQLALQEAAKASLKARRGRVRRGLNSLTTSDGTEKGGYICDVCGNFYEKRGRM 238

  Fly   371 SSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKMLLKQHMRTHSG 435
            ..|.:.|....:|.|..|...|..|.....|:..|||.||:||:.|.::|..:.:||.|...|.|
  Fly   239 MEHRRRHDGICQYACELCDAKFQVREQLRKHMYSHTGSKPYKCSFCSRQFFYESVLKSHENVHRG 303

  Fly   436 EKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTH 485
            .|||.|.||.|:||...::|.|..:||.||.:.|..|.|.|...||::.|
  Fly   304 IKPYVCKVCDKAFAYAHSLTKHELIHSDIKLYRCDYCNKDFRLLHHMRQH 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	1/6 (17%)
		COG5048	<316..502	CDD:227381	55/177 (31%)
		C2H2 Zn finger	327..347	CDD:275368	4/26 (15%)
		zf-C2H2	356..377	CDD:278523	5/20 (25%)
		C2H2 Zn finger	357..377	CDD:275368	5/19 (26%)
		zf-H2C2_2	369..394	CDD:290200	6/24 (25%)
		C2H2 Zn finger	385..405	CDD:275368	5/19 (26%)
		zf-H2C2_2	397..422	CDD:290200	10/24 (42%)
		C2H2 Zn finger	413..433	CDD:275368	6/19 (32%)
		zf-H2C2_2	426..449	CDD:290200	12/22 (55%)
		zf-C2H2	439..461	CDD:278523	9/21 (43%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		zf-C2H2	467..489	CDD:278523	7/19 (37%)
		C2H2 Zn finger	469..489	CDD:275368	7/17 (41%)
		C2H2 Zn finger	497..515	CDD:275368
Zif	NP_001189188.1	zf-AD	9..87	CDD:285071
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		COG5048	<250..369	CDD:227381	42/104 (40%)
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		zf-H2C2_2	266..288	CDD:290200	9/21 (43%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		zf-H2C2_2	294..318	CDD:290200	13/23 (57%)
		C2H2 Zn finger	309..329	CDD:275368	8/19 (42%)
		C2H2 Zn finger	337..353	CDD:275368	6/15 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840