DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and lst-5

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_872063.2	Gene:	lst-5 / 353399	WormBaseID:	WBGene00016890	Length:	346	Species:	Caenorhabditis elegans

Alignment Length:	161	Identity:	45/161 - (27%)
Similarity:	70/161 - (43%)	Gaps:	16/161 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 HKSPRYECADCGKGFSQLRNYKYH-LSVHRGTKEF-----AAECPECGKTFNDKGYLSSHLKIHR 378
            ||  .|:|.:|.:.|:...|.:.| :..|.|.|..     :::|..|||.::....|:.|:....
Worm   106 HK--EYQCDECDRMFTLKHNLQNHFVQYHMGCKTLHKACVSSKCDICGKIYSAVSVLAEHMLNEH 168

  Fly   379 NR--KEYECPYCPKSFNQRVAFNMHVRIHTGVKPH----KCNECGKRFSRKMLLKQHMRTHSGEK 437
            ||  .:.|||.|.:.|..:.|...|::.|...:.|    :|.....||:|:  |.:|:|.....|
Worm   169 NRYLDQIECPDCHEFFLTQTALQKHMKEHKREEKHCPYKECRGIKFRFNRE--LNEHVRLQHKSK 231

  Fly   438 PYQCSVCGKSFADRSNMTLHHRLHSGIKPFS 468
            ...|.||...|...|....|.:.|....|.|
Worm   232 ELSCCVCNMVFRQLSAKIKHEKTHEKGSPIS 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	45/161 (28%)
		COG5048	<316..502	CDD:227381	45/161 (28%)
		C2H2 Zn finger	327..347	CDD:275368	5/20 (25%)
		zf-C2H2	356..377	CDD:278523	6/20 (30%)
		C2H2 Zn finger	357..377	CDD:275368	6/19 (32%)
		zf-H2C2_2	369..394	CDD:290200	9/26 (35%)
		C2H2 Zn finger	385..405	CDD:275368	6/19 (32%)
		zf-H2C2_2	397..422	CDD:290200	7/28 (25%)
		C2H2 Zn finger	413..433	CDD:275368	7/19 (37%)
		zf-H2C2_2	426..449	CDD:290200	7/22 (32%)
		zf-C2H2	439..461	CDD:278523	6/21 (29%)
		C2H2 Zn finger	441..461	CDD:275368	6/19 (32%)
		zf-C2H2	467..489	CDD:278523	1/2 (50%)
		C2H2 Zn finger	469..489	CDD:275368	45/161 (28%)
		C2H2 Zn finger	497..515	CDD:275368
lst-5	NP_872063.2	C2H2 Zn finger	111..132	CDD:275368	5/20 (25%)
		C2H2 Zn finger	147..168	CDD:275368	6/20 (30%)
		C2H2 Zn finger	177..197	CDD:275368	6/19 (32%)
		C2H2 Zn finger	208..227	CDD:275368	7/20 (35%)
		C2H2 Zn finger	235..255	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910