DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and Zfp629

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001101021.2	Gene:	Zfp629 / 308998	RGDID:	1306257	Length:	866	Species:	Rattus norvegicus

Alignment Length:	627	Identity:	174/627 - (27%)
Similarity:	233/627 - (37%)	Gaps:	132/627 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PSPARTSPTNGVQNLGAGAQLPPAQVTDFSISKILGKERKSAQDTSTNILDL---SKSSSNSIRS 71
            |..:|.:...|.:: |...:.|..:.:...|  |||...:|.:....:.:.|   |:.:|....|
  Rat    15 PEESRNNVHRGAES-GNEEESPQQESSGEEI--ILGDPAQSPESKDPSEMPLESPSQDASAPQDS 76

  Fly    72 PQALGGLA-----IPSTPYASGAYSMLPPDLVAMA-----------------NATKFYAQFFPHL 114
            |..||..:     .|..|.|        |::|...                 |:|.......|.|
  Rat    77 PTPLGSSSSLDHQTPMDPSA--------PEVVPSPSEWTKETSWQWGTFTTWNSTPAVTASEPSL 133

  Fly   115 LPAYAAAAAAA---------GLSTPPTSPYQTHQ--HQQHLPNQQKRFFAPYVINGSVPPPPPLQ 168
            ........:.|         |.|....|....||  |....||....      ...|......|.
  Rat   134 RELVQGRPSGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSE------CGKSFTQSSHLV 192

  Fly   169 QQQQPLIRTKSTACTRPDCPECLDY------YQRLQTG--GYKQTAPLISPAASSVSSSTGSIRP 225
            |.|:.....|...|  |||.:|..:      :||..||  .||.|
  Rat   193 QHQRTHTGEKPYKC--PDCGKCFSWSSNLVQHQRTHTGEKPYKCT-------------------- 235

  Fly   226 VRDLIMSATGGAASTNISLTTVTNLSLNSVQATAVGMMPKMTGGLITTAVGSNSGAIGGIGGYNA 290
                         ....:.|..|||..:  |.:..|..|...|. ...|...:|..|    .:.|
  Rat   236 -------------ECEKAFTQSTNLIKH--QRSHTGEKPYKCGE-CRRAFYRSSDLI----QHQA 280

  Fly   291 TSAEEISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFA 354
            |...|..|||..|.|.||.:..|..|:|.|...: |.|.:|||.|.|......|...|.|.|.:
  Rat   281 THTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHTGEKPY- 344

  Fly   355 AECPECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKR 419
             ||.||||:|.....|..|.:.|.....::||.|.|:|........|.|.|||.:|:||.||||.
  Rat   345 -ECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKS 408

  Fly   420 FSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKT 484
            ||....|..|.|.|.||:||.|:.|||||...|.:..|.|:|:|.||:.|..|.|:|.:..||..
  Rat   409 FSVSSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQ 473

  Fly   485 HLNYHTGCKPYVCPHPNCNQAFTQSSNMRTHAK-----------KC-----QYRPLDGLTVTSSA 533
            |...|||.|||.|  |.|.::|:||||:.||.:           .|     :.:.|:...|....
  Rat   474 HRRTHTGEKPYKC--PECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAQELEQHRVIHER 536

  Fly   534 LPVPGKQQTGPPPTLAMAMAQTFQMPPPPGV-----LTPGSG 570
            ...|.::..|..   .:.:.....|.||||.     |..|.|
  Rat   537 GKTPARRAQGDG---LLGLGDPALMTPPPGAKPHKCLVCGKG 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	8/19 (42%)
		COG5048	<316..502	CDD:227381	79/186 (42%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		zf-C2H2	356..377	CDD:278523	9/20 (45%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		zf-H2C2_2	369..394	CDD:290200	8/24 (33%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		zf-H2C2_2	397..422	CDD:290200	13/24 (54%)
		C2H2 Zn finger	413..433	CDD:275368	10/19 (53%)
		zf-H2C2_2	426..449	CDD:290200	13/22 (59%)
		zf-C2H2	439..461	CDD:278523	10/21 (48%)
		C2H2 Zn finger	441..461	CDD:275368	9/19 (47%)
		zf-C2H2	467..489	CDD:278523	7/21 (33%)
		C2H2 Zn finger	469..489	CDD:275368	7/19 (37%)
		C2H2 Zn finger	497..515	CDD:275368	8/17 (47%)
Zfp629	NP_001101021.2	fibronec_FbpA	<26..>147	CDD:411474	24/131 (18%)
		zf-C2H2	148..170	CDD:395048	5/21 (24%)
		C2H2 Zn finger	150..170	CDD:275368	5/19 (26%)
		zf-C2H2	177..198	CDD:395048	4/26 (15%)
		C2H2 Zn finger	178..198	CDD:275368	4/25 (16%)
		COG5048	202..510	CDD:227381	122/353 (35%)
		C2H2 Zn finger	206..226	CDD:275368	7/21 (33%)
		C2H2 Zn finger	234..254	CDD:275368	6/54 (11%)
		C2H2 Zn finger	262..282	CDD:275368	5/24 (21%)
		C2H2 Zn finger	290..310	CDD:275368	8/19 (42%)
		C2H2 Zn finger	318..338	CDD:275368	7/19 (37%)
		C2H2 Zn finger	346..366	CDD:275368	8/19 (42%)
		C2H2 Zn finger	374..394	CDD:275368	7/19 (37%)
		C2H2 Zn finger	402..422	CDD:275368	10/19 (53%)
		C2H2 Zn finger	430..450	CDD:275368	9/19 (47%)
		C2H2 Zn finger	458..478	CDD:275368	7/19 (37%)
		C2H2 Zn finger	486..506	CDD:275368	10/21 (48%)
		C2H2 Zn finger	514..534	CDD:275368	3/19 (16%)
		C2H2 Zn finger	569..589	CDD:275368	3/7 (43%)
		C2H2 Zn finger	662..682	CDD:275368
		C2H2 Zn finger	714..734	CDD:275368
		C2H2 Zn finger	767..787	CDD:275368
		C2H2 Zn finger	841..861	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000