DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and Zbtb11

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_038944302.1	Gene:	Zbtb11 / 304010	RGDID:	1308275	Length:	1092	Species:	Rattus norvegicus

Alignment Length:	432	Identity:	108/432 - (25%)
Similarity:	163/432 - (37%)	Gaps:	138/432 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 RTKSTACTRPDCPECLDYYQRLQTGGYKQT---APLISPA------ASSVSSSTGSIRPVRDLIM 231
            |.:...|  |.|.:...|...|:....:.|   ||..|.:      ||..||..|  |..|:.|.
  Rat   592 RARDYKC--PLCKKQFQYSASLRAHLIRHTRKDAPTSSSSNSTSNEASGASSEKG--RTKREFIC 652

  Fly   232 SATGGAASTNISLTTVTNLSLNSVQATAVGMMPKMTGGLITTAVGSNSGAIGGIGGYNATSAEEI 296
            |..|.      :|..:.:|.::.::.|  |:.|
  Rat   653 SICGR------TLPKLYSLRIHMLKHT--GVKP-------------------------------- 677

  Fly   297 SYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPEC 360
             :.|::|.|.|.....|:.|:..|:|.: ::|..|.|.|...|:.:.|:|:|.|..::.  |..|
  Rat   678 -HACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFVTKRSLQEHMSIHTGESKYF--CSVC 739

  Fly   361 GKTFNDKGYLSSHLKIHRNRKE---YECP------------------------------------ 386
            ||:|:....||.|||.|:.:.|   |.|.
  Rat   740 GKSFHRGSGLSKHLKKHQPKPEVRGYHCTQLHMDQVWQCFQLLILSASKLSRVFPGSSCKSPVFP 804

  Fly   387 ----YCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKS 447
                .|.|||.:......|:..|.||||.:|..|.|.:|.|.....|:::||..:||:|::|||.
  Rat   805 SDWIQCEKSFFEARDLRQHMNKHLGVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPYRCNICGKE 869

  Fly   448 FAD-----------------RSNMTL-------------------HHRLHSGIKPFSCPLCPKAF 476
            |.:                 |:...|                   |...|.|:|||.|..|..|:
  Rat   870 FYEKALFRRHVKKATHGKKGRAKQNLERVCDQCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAW 934

  Fly   477 TKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTHAKK 518
            .....||.|:..|||.:||||  |.|::|:..:..:|.|..|
  Rat   935 ADARSLKRHVRTHTGERPYVC--PVCSEAYIDARTLRKHMTK 974

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	6/19 (32%)
		COG5048	<316..502	CDD:227381	73/265 (28%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		zf-C2H2	356..377	CDD:278523	10/20 (50%)
		C2H2 Zn finger	357..377	CDD:275368	10/19 (53%)
		zf-H2C2_2	369..394	CDD:290200	13/67 (19%)
		C2H2 Zn finger	385..405	CDD:275368	6/59 (10%)
		zf-H2C2_2	397..422	CDD:290200	9/24 (38%)
		C2H2 Zn finger	413..433	CDD:275368	6/19 (32%)
		zf-H2C2_2	426..449	CDD:290200	9/22 (41%)
		zf-C2H2	439..461	CDD:278523	9/57 (16%)
		C2H2 Zn finger	441..461	CDD:275368	8/55 (15%)
		zf-C2H2	467..489	CDD:278523	7/21 (33%)
		C2H2 Zn finger	469..489	CDD:275368	6/19 (32%)
		C2H2 Zn finger	497..515	CDD:275368	5/17 (29%)
Zbtb11	XP_038944302.1	Integrase_H2C2	68..120	CDD:407771
		BTB_POZ_ZBTB11	195..312	CDD:349511
		PRK12387	<556..621	CDD:183492	7/30 (23%)
		C2H2 Zn finger	570..590	CDD:275368
		C2H2 Zn finger	598..618	CDD:275368	5/21 (24%)
		C2H2 Zn finger	652..672	CDD:275368	4/25 (16%)
		zf-H2C2_2	664..689	CDD:404364	8/59 (14%)
		C2H2 Zn finger	680..700	CDD:275368	6/19 (32%)
		COG5048	695..>801	CDD:227381	26/107 (24%)
		C2H2 Zn finger	708..728	CDD:275368	7/19 (37%)
		C2H2 Zn finger	736..756	CDD:275368	10/19 (53%)
		C2H2 Zn finger	809..827	CDD:275368	5/17 (29%)
		zf-H2C2_2	819..843	CDD:404364	9/23 (39%)
		C2H2 Zn finger	835..855	CDD:275368	6/19 (32%)
		C2H2 Zn finger	863..885	CDD:275368	5/21 (24%)
		C2H2 Zn finger	899..919	CDD:275368	1/19 (5%)
		C2H2 Zn finger	927..947	CDD:275368	6/19 (32%)
		zf-H2C2_2	939..962	CDD:404364	12/24 (50%)
		C2H2 Zn finger	955..976	CDD:275368	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24384
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100