DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15269 and ZNF621

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001091884.1 Gene:ZNF621 / 285268 HGNCID:24787 Length:439 Species:Homo sapiens


Alignment Length:299 Identity:106/299 - (35%)
Similarity:135/299 - (45%) Gaps:29/299 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   285 IGGYNATSAEEISYKCRICEKVFGCSET--LQAHEKTHKSPRYECADCGKGFSQLRNYKYHLSVH 347
            :||.....::...:|.:..::.|..:..  |:...|.     |||.:|||.|........|...|
Human   114 VGGLLRNVSQHFDFKRKALKQTFNLNPNLILRGGMKF-----YECKECGKIFRYNSKLIRHQMSH 173

  Fly   348 RGTKEFAAECPECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHK 412
            .|.|.|  :|.||||.|........|.|.|.....|||..|.|..:...|...|.|||||.||::
Human   174 TGEKPF--KCKECGKAFKSSYDCIVHEKNHIGEGPYECKECGKGLSSNTALTQHQRIHTGEKPYE 236

  Fly   413 CNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFT 477
            |.||||.|.|.....||.|.|:|||.|:|..|.|:|..||...:|.|:|:|.||:.|..|.||||
Human   237 CKECGKAFRRSAAYLQHQRLHTGEKLYKCKECWKAFGCRSLFIVHQRIHTGEKPYQCKECGKAFT 301

  Fly   478 KKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTHAKKCQYRPLD--GLTVTSSALPVPGKQ 540
            :|.....|...|||.|||.|  ..|.:||....:...|.|   ..|::  .:.|...:|..|...
Human   302 QKIASIQHQRVHTGEKPYEC--KVCGKAFKWYGSFVQHQK---LHPVEKKPVKVLGPSLVSPQCS 361

  Fly   541 QTGPPPTL------AMAMA---QTFQMPPPPGVLTPGSG 570
            ....||.|      |.|:|   .||    |..||.|.||
Human   362 SPAIPPVLLQGSCSASAVAVPSLTF----PHAVLIPTSG 396

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 3/21 (14%)
COG5048 <316..502 CDD:227381 78/185 (42%)
C2H2 Zn finger 327..347 CDD:275368 6/19 (32%)
zf-C2H2 356..377 CDD:278523 8/20 (40%)
C2H2 Zn finger 357..377 CDD:275368 8/19 (42%)
zf-H2C2_2 369..394 CDD:290200 8/24 (33%)
C2H2 Zn finger 385..405 CDD:275368 6/19 (32%)
zf-H2C2_2 397..422 CDD:290200 15/24 (63%)
C2H2 Zn finger 413..433 CDD:275368 10/19 (53%)
zf-H2C2_2 426..449 CDD:290200 11/22 (50%)
zf-C2H2 439..461 CDD:278523 9/21 (43%)
C2H2 Zn finger 441..461 CDD:275368 8/19 (42%)
zf-C2H2 467..489 CDD:278523 8/21 (38%)
C2H2 Zn finger 469..489 CDD:275368 8/19 (42%)
C2H2 Zn finger 497..515 CDD:275368 4/17 (24%)
ZNF621NP_001091884.1 KRAB 11..71 CDD:214630
COG4049 145..198 CDD:226535 19/59 (32%)
C2H2 Zn finger 153..173 CDD:275368 6/19 (32%)
zf-H2C2_2 166..190 CDD:316026 11/25 (44%)
C2H2 Zn finger 209..229 CDD:275368 6/19 (32%)
zf-H2C2_2 221..246 CDD:316026 15/24 (63%)
C2H2 Zn finger 237..257 CDD:275368 10/19 (53%)
C2H2 Zn finger 265..285 CDD:275368 8/19 (42%)
zf-H2C2_2 281..302 CDD:316026 11/20 (55%)
C2H2 Zn finger 293..313 CDD:275368 8/19 (42%)
zf-H2C2_2 308..329 CDD:316026 10/22 (45%)
C2H2 Zn finger 321..341 CDD:275368 6/24 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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