DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and Zbtb11

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_766614.2	Gene:	Zbtb11 / 271377	MGIID:	2443876	Length:	1050	Species:	Mus musculus

Alignment Length:	612	Identity:	142/612 - (23%)
Similarity:	222/612 - (36%)	Gaps:	184/612 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PSPARTSPTNGVQNLGAGAQLPPAQVT--DFSISKILGKERKSAQDTSTNILDLSK--SSSNSIR 70
            |.|   .|..|..:|...:..|.:.||  |..::.:..|..|.      |:.:.|:  |.:.:..
Mouse   402 PEP---HPEMGTASLAKESNQPESAVTREDGIVASVHPKISKE------NVTNASQEDSDTGNDT 457

  Fly    71 SPQALGGLAIPSTPYASGAYSMLPPDLVAMANATKFYAQFFPHLLPAYAAAAAAAGLSTPPTSPY 135
            ||:.:|....|....:.|..|.....|......|.                      |.|....|
Mouse   458 SPEDIGAKDCPDHSQSPGQPSKDEDTLTEATEKTD----------------------SGPDDDTY 500

  Fly   136 QTHQHQQHL---------PNQQKRFFAPYVINGSVPPPPPLQQQQQPLIR------------TKS 179
            ::...|:.:         ...:|:......|:.|.     :||..|.|::            .:|
Mouse   501 RSRLRQRSVNEGGYIRLHKGMEKKLQKRKAISKSA-----VQQVAQKLVQRGKKMKQPKRDAKES 560

  Fly   180 TACTRPDCPEC-------------------------------LDYYQRLQTGGYKQTAPLISPAA 213
            |..|...|.||                               ..|...|:....:.|......::
Mouse   561 TEETAHKCGECGMVFPRRYAFIMHTLKHERARDYKCPLCKKQFQYSASLRAHLIRHTRKEAPTSS 625

  Fly   214 SSVSSST----GSI---RPVRDLIMSATGGAASTNISLTTVTNLSLNSVQATAVGMMPKMTGGLI 271
            ||.|:||    ||.   |..|:.|.|..|.      :|..:.:|.::.::.|  |:.|
Mouse   626 SSNSTSTEASGGSSEKGRTKREFICSICGR------TLPKLYSLRIHMLKHT--GVKP------- 675

  Fly   272 TTAVGSNSGAIGGIGGYNATSAEEISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFS 335
                                      :.|::|.|.|.....|:.|:..|:|.: ::|..|.|.|.
Mouse   676 --------------------------HACQVCGKTFIYKHGLKLHQSLHQSQKQFQCELCVKSFV 714

  Fly   336 QLRNYKYHLSVHRGTKEFAAECPECGKTFNDKGYLSSHLKIHRNRKE---YECPYCPKSFNQRVA 397
            ..|:.:.|:|:|.|..::.  |..|||:|:....||.|||.|:.:.|   |.|..|.|||.:...
Mouse   715 TKRSLQEHMSIHTGESKYF--CSICGKSFHRGSGLSKHLKKHQPKPEVRGYHCTQCEKSFFEARD 777

  Fly   398 FNMHVRIHTGVKPHKCNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFAD------------ 450
            ...|:..|.||||.:|..|.|.:|.|.....|:::||..:||:|::|||.|.:
Mouse   778 LRQHMNKHLGVKPFQCQFCDKCYSWKKDWYSHVKSHSVTEPYRCNICGKEFYEKALFRRHVKKAT 842

  Fly   451 -----RSNMTL-------------------HHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTG 491
                 |:...|                   |...|.|:|||.|..|..|:.....||.|:..|||
Mouse   843 HGKKGRAKQNLERVCDQCGRKFTQLREYRRHMNNHEGVKPFECLTCGVAWADARSLKRHVRTHTG 907

  Fly   492 CKPYVCPHPNCNQAFTQSSNMRTHAKK 518
            .:||||  |.|::|:..:..:|.|..|
Mouse   908 ERPYVC--PVCSEAYIDARTLRKHMTK 932

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	6/19 (32%)
		COG5048	<316..502	CDD:227381	73/225 (32%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		zf-C2H2	356..377	CDD:278523	10/20 (50%)
		C2H2 Zn finger	357..377	CDD:275368	10/19 (53%)
		zf-H2C2_2	369..394	CDD:290200	13/27 (48%)
		C2H2 Zn finger	385..405	CDD:275368	6/19 (32%)
		zf-H2C2_2	397..422	CDD:290200	9/24 (38%)
		C2H2 Zn finger	413..433	CDD:275368	6/19 (32%)
		zf-H2C2_2	426..449	CDD:290200	9/22 (41%)
		zf-C2H2	439..461	CDD:278523	9/57 (16%)
		C2H2 Zn finger	441..461	CDD:275368	8/55 (15%)
		zf-C2H2	467..489	CDD:278523	7/21 (33%)
		C2H2 Zn finger	469..489	CDD:275368	6/19 (32%)
		C2H2 Zn finger	497..515	CDD:275368	5/17 (29%)
Zbtb11	NP_766614.2	Integrase_H2C2	68..120	CDD:375431
		BTB_POZ_ZBTB11	195..312	CDD:349511
		Trypan_PARP	<367..>421	CDD:392002	5/21 (24%)
		C2H2 Zn finger	568..588	CDD:275368	3/19 (16%)
		C2H2 Zn finger	596..616	CDD:275368	2/19 (11%)
		C2H2 Zn finger	650..670	CDD:275368	4/25 (16%)
		COG5048	<664..837	CDD:227381	59/209 (28%)
		C2H2 Zn finger	678..698	CDD:275368	6/19 (32%)
		C2H2 Zn finger	706..726	CDD:275368	7/19 (37%)
		C2H2 Zn finger	734..754	CDD:275368	10/19 (53%)
		C2H2 Zn finger	765..785	CDD:275368	6/19 (32%)
		C2H2 Zn finger	793..813	CDD:275368	6/19 (32%)
		C2H2 Zn finger	857..877	CDD:275368	1/19 (5%)
		C2H2 Zn finger	885..905	CDD:275368	6/19 (32%)
		zf-H2C2_2	897..920	CDD:372612	12/24 (50%)
		C2H2 Zn finger	913..934	CDD:275368	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24384
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100