DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and Zfp668

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001349118.1	Gene:	Zfp668 / 244219	MGIID:	2442943	Length:	619	Species:	Mus musculus

Alignment Length:	327	Identity:	100/327 - (30%)
Similarity:	148/327 - (45%)	Gaps:	54/327 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   290 ATSAEEISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEF 353
            |:.|.|:.::|..|.|.:|....|:.|::.|...| |.|.||||.|:....::.|...|.|.:.:
Mouse   132 ASHAGELPFRCTHCPKAYGTLSKLKIHQRGHTGERPYACPDCGKSFADPSVFRKHRRTHAGLRPY 196

  Fly   354 AAE--------------------------CPECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSF 392
            :.|                          |.||||:|:....|:.|.:||..:|.|.||.|.|.|
Mouse   197 SCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGKGF 261

  Fly   393 NQRVAFNMHVRIHTGVKPHKCNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLH 457
            .|..::..|.|.|:|.||..|..||:.||.....::|.|.|.|.|||:|..|||.|...:::.:|
Mouse   262 TQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEGVKPYRCEKCGKDFRQPADLAMH 326

  Fly   458 HRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTHAK-KCQY 521
            .|:|:|.:||.|..|.|.|.....||.|...|:|.:|:.|  ..|.:||.:.:::..|:: ....
Mouse   327 RRVHTGDRPFKCLQCDKTFVASWDLKRHALVHSGQRPFRC--EECGRAFAERASLTKHSRMHSGE 389

  Fly   522 RPL------DGLTVTSSALPVP----GKQQTGPPP----TLAMAMAQTFQMPPPPGVLTPGSGPS 572
            ||.      ....|.||.....    ..:.||..|    .|.:|:        |.||:  |.|.:
Mouse   390 RPFHCNACGKSFVVLSSLRKHERTHRSNETTGAAPQQELVLGLAL--------PVGVV--GEGSA 444

  Fly   573 QP 574
            .|
Mouse   445 AP 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	6/19 (32%)
		COG5048	<316..502	CDD:227381	72/212 (34%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		zf-C2H2	356..377	CDD:278523	9/46 (20%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		zf-H2C2_2	369..394	CDD:290200	11/24 (46%)
		C2H2 Zn finger	385..405	CDD:275368	8/19 (42%)
		zf-H2C2_2	397..422	CDD:290200	10/24 (42%)
		C2H2 Zn finger	413..433	CDD:275368	7/19 (37%)
		zf-H2C2_2	426..449	CDD:290200	11/22 (50%)
		zf-C2H2	439..461	CDD:278523	8/21 (38%)
		C2H2 Zn finger	441..461	CDD:275368	7/19 (37%)
		zf-C2H2	467..489	CDD:278523	8/21 (38%)
		C2H2 Zn finger	469..489	CDD:275368	7/19 (37%)
		C2H2 Zn finger	497..515	CDD:275368	4/17 (24%)
Zfp668	NP_001349118.1	C2H2 Zn finger	24..44	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..74
		COG5048	65..419	CDD:227381	89/288 (31%)
		C2H2 Zn finger	86..106	CDD:275368
		C2H2 Zn finger	114..134	CDD:275368	1/1 (100%)
		C2H2 Zn finger	142..162	CDD:275368	6/19 (32%)
		C2H2 Zn finger	170..190	CDD:275368	7/19 (37%)
		C2H2 Zn finger	198..218	CDD:275368	1/19 (5%)
		C2H2 Zn finger	226..246	CDD:275368	8/19 (42%)
		COG5048	248..598	CDD:227381	68/211 (32%)
		C2H2 Zn finger	254..274	CDD:275368	8/19 (42%)
		C2H2 Zn finger	282..302	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..330	CDD:275368	7/19 (37%)
		C2H2 Zn finger	338..358	CDD:275368	7/19 (37%)
		C2H2 Zn finger	366..386	CDD:275368	5/21 (24%)
		C2H2 Zn finger	394..414	CDD:275368	3/19 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	491..513
		C2H2 Zn finger	518..538	CDD:275368
		C2H2 Zn finger	546..566	CDD:275368
		C2H2 Zn finger	574..594	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910