DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and Zfp768

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_666314.1	Gene:	Zfp768 / 233890	MGIID:	2384582	Length:	568	Species:	Mus musculus

Alignment Length:	506	Identity:	141/506 - (27%)
Similarity:	193/506 - (38%)	Gaps:	131/506 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 PTSP---YQTHQHQQHLPNQQKRFFAPYVINGSVPPPP-------------PLQQQQQPLIRTKS 179
            |.||   .|:.:.:...|..:.|  :|    |.|||.|             |..:.|.|....:|
Mouse    70 PQSPEFESQSPRFEPESPGFESR--SP----GFVPPSPEFAPRSPESDPQSPEFESQSPKYEPRS 128

  Fly   180 TACTRPDCPECLDYYQRL----------------QTGGYKQTAPLISPAASSVSSSTGSIR---P 225
            ..| .|..|.|.....|.                |:.||:..:|...|..|.........:   |
Mouse   129 PGC-HPRSPGCEPGSPRYEPKSPGYGSKSPEFESQSPGYESQSPGYEPQNSGDGVQNSEFKTHSP 192

  Fly   226 VRDLIMSATGGAASTNISLTTVTNLSLN-------------SVQATAVGMMP--KMTGGLITTA- 274
            ..:...|.....|...:|......||::             ..|.|  |.:|  .|..|.:..|
Mouse   193 EFETQSSKFQEGAEMPLSPEEKNPLSISLGVHPLDSFTQGFGEQPT--GALPPFDMPSGALLAAP 255

  Fly   275 -----------------VGSNSG-AIGGIG-------------GYNATSAE-------EISYKCR 301
                             .|...| |.||.|             |..:|..:       |..|||.
Mouse   256 QFEMLQNPLNLTGTLRGPGRRGGRARGGQGPRPNICGICGKSFGRGSTLIQHQRIHTGEKPYKCE 320

  Fly   302 ICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPECGKTFN 365
            :|.|.|..|..|..|::||...| |:|..|||.|:.......|...|.|.|.:  :||.|||.|.
Mouse   321 VCSKAFSQSSDLIKHQRTHTGERPYKCPRCGKAFADSSYLLRHQRTHSGQKPY--KCPHCGKAFG 383

  Fly   366 DKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKMLLKQHM 430
            |..||..|.:.|.:.:.|.||.|.|.::|..:...|.|:|||.:|..|..|||.||::..|..|.
Mouse   384 DSSYLLRHQRTHSHERPYSCPECGKCYSQNSSLRSHQRVHTGQRPFSCGICGKSFSQRSALIPHA 448

  Fly   431 RTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPY 495
            |:|:.|||::|..|||.|...|.:.:|.|.|...:.:|||.|.|.|.:...|..|...|||.:||
Mouse   449 RSHAREKPFKCPECGKRFGQSSVLAIHARTHLPGRTYSCPDCGKTFNRSSTLIQHQRSHTGERPY 513

  Fly   496 VC------------------------PH--PNCNQAFTQSSNM----RTHA 516
            .|                        |:  .:|.:||:|||::    ||||
Mouse   514 RCAVCGKGFCRSSTLLQHHRVHSGERPYKCDDCGKAFSQSSDLIRHQRTHA 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	7/19 (37%)
		COG5048	<316..502	CDD:227381	74/212 (35%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		zf-C2H2	356..377	CDD:278523	10/20 (50%)
		C2H2 Zn finger	357..377	CDD:275368	10/19 (53%)
		zf-H2C2_2	369..394	CDD:290200	9/24 (38%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		zf-H2C2_2	397..422	CDD:290200	11/24 (46%)
		C2H2 Zn finger	413..433	CDD:275368	9/19 (47%)
		zf-H2C2_2	426..449	CDD:290200	11/22 (50%)
		zf-C2H2	439..461	CDD:278523	8/21 (38%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		zf-C2H2	467..489	CDD:278523	8/21 (38%)
		C2H2 Zn finger	469..489	CDD:275368	7/19 (37%)
		C2H2 Zn finger	497..515	CDD:275368	9/47 (19%)
Zfp768	NP_666314.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..223		33/159 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	228..247		4/20 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	264..287		6/22 (27%)
		C2H2 Zn finger	291..311	CDD:275368	2/19 (11%)
		zf-H2C2_2	304..328	CDD:290200	7/23 (30%)
		C2H2 Zn finger	319..339	CDD:275368	7/19 (37%)
		COG5048	<327..532	CDD:227381	75/206 (36%)
		zf-H2C2_2	331..355	CDD:290200	10/23 (43%)
		C2H2 Zn finger	347..367	CDD:275368	6/19 (32%)
		zf-H2C2_2	359..382	CDD:290200	9/24 (38%)
		zf-C2H2	373..395	CDD:278523	10/23 (43%)
		C2H2 Zn finger	375..395	CDD:275368	10/19 (53%)
		zf-C2H2	401..423	CDD:278523	8/21 (38%)
		C2H2 Zn finger	403..423	CDD:275368	7/19 (37%)
		zf-H2C2_2	415..440	CDD:290200	11/24 (46%)
		C2H2 Zn finger	431..451	CDD:275368	9/19 (47%)
		zf-H2C2_2	447..466	CDD:290200	10/18 (56%)
		C2H2 Zn finger	459..479	CDD:275368	8/19 (42%)
		zf-C2H2	485..507	CDD:278523	8/21 (38%)
		C2H2 Zn finger	487..507	CDD:275368	7/19 (37%)
		zf-H2C2_2	500..522	CDD:290200	8/21 (38%)
		C2H2 Zn finger	515..535	CDD:275368	1/19 (5%)
		zf-H2C2_2	528..552	CDD:290200	4/23 (17%)
		zf-C2H2	541..563	CDD:278523	7/21 (33%)
		C2H2 Zn finger	543..563	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24384
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100