DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15269 and ZNF92

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_689839.1 Gene:ZNF92 / 168374 HGNCID:13168 Length:586 Species:Homo sapiens


Alignment Length:299 Identity:112/299 - (37%)
Similarity:146/299 - (48%) Gaps:29/299 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly   235 GGAASTNISLTTV-----------------TNLSLNSVQATAVGMMPKMTGGLITTAVGSNSGAI 282
            ||....|..|||.                 .|::.|.::.|  |..|......     |.:...:
Human   128 GGYNGLNQCLTTTDSKIFQCDKYVKVFHKFPNVNRNKIRHT--GKKPFKCKNR-----GKSFCML 185

  Fly   283 GGIGGYNATSAEEISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSV 346
            ..:..:......|.||||..|.|.|..|.||..|:..|...: |:|.:|||.|::..|...|..:
Human   186 SQLTQHKKIHTREYSYKCEECGKAFNWSSTLTKHKIIHTGEKPYKCEECGKAFNRSSNLTKHKII 250

  Fly   347 HRGTKEFAAECPECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPH 411
            |.|.|.:  :|.||||.||....|:.|.:||...|.|:|..|.|:|||....|.|.|||...||:
Human   251 HTGEKPY--KCEECGKAFNRSSTLTKHKRIHTEEKPYKCEECGKAFNQFSILNKHKRIHMEDKPY 313

  Fly   412 KCNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAF 476
            ||.||||.|....:||:|...|:|||||:|..|||:|...||:|.|..:|:|.||:.|..|.|||
Human   314 KCEECGKAFRVFSILKKHKIIHTGEKPYKCEECGKAFNQFSNLTKHKIIHTGEKPYKCDECGKAF 378

  Fly   477 TKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTH 515
            .:...|..|...|||.|||.|  ..|.:||.|||.:..|
Human   379 NQSSTLTKHKRIHTGEKPYKC--EECGKAFKQSSTLTEH 415

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 8/19 (42%)
COG5048 <316..502 CDD:227381 82/186 (44%)
C2H2 Zn finger 327..347 CDD:275368 7/19 (37%)
zf-C2H2 356..377 CDD:278523 9/20 (45%)
C2H2 Zn finger 357..377 CDD:275368 9/19 (47%)
zf-H2C2_2 369..394 CDD:290200 10/24 (42%)
C2H2 Zn finger 385..405 CDD:275368 9/19 (47%)
zf-H2C2_2 397..422 CDD:290200 14/24 (58%)
C2H2 Zn finger 413..433 CDD:275368 9/19 (47%)
zf-H2C2_2 426..449 CDD:290200 13/22 (59%)
zf-C2H2 439..461 CDD:278523 10/21 (48%)
C2H2 Zn finger 441..461 CDD:275368 9/19 (47%)
zf-C2H2 467..489 CDD:278523 7/21 (33%)
C2H2 Zn finger 469..489 CDD:275368 7/19 (37%)
C2H2 Zn finger 497..515 CDD:275368 7/17 (41%)
ZNF92NP_689839.1 KRAB 4..64 CDD:214630
KRAB 4..43 CDD:279668
C2H2 Zn finger 175..195 CDD:275368 1/24 (4%)
C2H2 Zn finger 203..223 CDD:275368 8/19 (42%)
zf-H2C2_2 216..240 CDD:290200 9/23 (39%)
COG5048 227..579 CDD:227381 87/193 (45%)
C2H2 Zn finger 231..251 CDD:275368 7/19 (37%)
zf-H2C2_2 243..268 CDD:290200 11/26 (42%)
C2H2 Zn finger 259..279 CDD:275368 9/19 (47%)
zf-H2C2_2 272..296 CDD:290200 10/23 (43%)
C2H2 Zn finger 287..307 CDD:275368 9/19 (47%)
zf-H2C2_2 300..322 CDD:290200 13/21 (62%)
C2H2 Zn finger 315..335 CDD:275368 9/19 (47%)
zf-H2C2_2 328..352 CDD:290200 14/23 (61%)
C2H2 Zn finger 343..363 CDD:275368 9/19 (47%)
zf-H2C2_2 355..380 CDD:290200 12/24 (50%)
C2H2 Zn finger 371..391 CDD:275368 7/19 (37%)
zf-H2C2_2 384..408 CDD:290200 12/25 (48%)
C2H2 Zn finger 399..419 CDD:275368 8/19 (42%)
zf-H2C2_2 412..435 CDD:290200 1/4 (25%)
C2H2 Zn finger 427..447 CDD:275368
C2H2 Zn finger 455..475 CDD:275368
zf-H2C2_2 468..492 CDD:290200
C2H2 Zn finger 483..503 CDD:275368
C2H2 Zn finger 539..556 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24384
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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