DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15269 and ZNF555

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:XP_011526018.1 Gene:ZNF555 / 148254 HGNCID:28382 Length:630 Species:Homo sapiens


Alignment Length:628 Identity:173/628 - (27%)
Similarity:251/628 - (39%) Gaps:179/628 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    27 GAQLP-PAQVTDF----SISKILGK--ERKSAQDTSTNI-LDLSKS-------SSNSIRSPQALG 76
            |.::| .:::..|    |.:.:|||  :..|.:|.:||. .:||::       .||.    |.  
Human    64 GEKIPKESKIATFTRNVSWASVLGKIWDSLSIEDQTTNQGRNLSRNHGLERLCESND----QC-- 122

  Fly    77 GLAIPSTPYASGAYSMLPPDLVAMANATKFYAQFFPHLLPAYAAAAAAAGLSTPPT-----SPYQ 136
            |.|:...|:.: .|..:||.:......|  |.:.|.|         ....|.:|.|     .|||
Human   123 GEALSQIPHLN-LYKKIPPGVKQYEYNT--YGKVFMH---------RRTSLKSPITVHTGHKPYQ 175

  Fly   137 THQHQQ------HL------PNQQKRFFAPYV--INGSVPPPPPLQQQQQPLIRTKS-------- 179
            ..:..|      ||      .|.::    |||  :.|...|            ||.|        
Human   176 CQECGQAYSCRSHLRMHVRTHNGER----PYVCKLCGKTFP------------RTSSLNRHVRIH 224

  Fly   180 TACTRPDCPEC----LDY-----YQRLQTG-------------GYKQT-----------APLISP 211
            ||....:|.:|    :|:     :.|..||             .|..|           .|....
Human   225 TAEKTYECKQCGKAFIDFSSLTSHLRSHTGEKPYKCKECGKAFSYSSTFRRHTITHTGEKPYKCK 289

  Fly   212 AASSVSSSTGSIRPVRDLIMSATG---------GAASTNISLTTVTNLSLNSVQATAVGMMP--- 264
            ..:...|.:.:.|  |.:| |.||         |.|.:..|       :......|..|..|   
Human   290 ECAEAFSYSSTFR--RHMI-SHTGEKPHKCKECGEAFSYSS-------AFRRHMITHTGEKPYEC 344

  Fly   265 KMTGGLITTAVGSNSGAIGGIGGYNATSAEEISYKCRICEKVFGCSETLQAHEKTHKSPR-YECA 328
            |..|   .|.:...|     ...:......|..|:|:.|.|.|...::.:.||:||...: |||.
Human   345 KQCG---KTFIYLQS-----FRRHERIHTGEKPYECKQCGKTFIYPQSFRRHERTHGGEKPYECN 401

  Fly   329 DCGKGFSQLRNYKYHLSVHRGTKEFAAECPECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFN 393
            .|||.||...:::.|:.||.|.|.:  ||.:||||||....|..|::.|...|.|||..|.|:|:
Human   402 QCGKAFSHPSSFRGHMRVHTGEKPY--ECKQCGKTFNWPISLRKHMRTHTREKPYECKQCGKAFS 464

  Fly   394 QRVAFNMHVRI----------------------------HTGVKPHKCNECGKRFSRKMLLKQHM 430
            ....|..|||:                            ||..|.:||.:|||.||...||:||:
Human   465 LSACFREHVRMHPEDKSYECKLCGKAFYCHISLQKHMRRHTAEKLYKCKQCGKAFSWPELLQQHV 529

  Fly   431 RTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPY 495
            |||:.||||:|..|||.|...|::.:|.|||:|.||:.|..|.|||.....|:.|:..||..|.|
Human   530 RTHTVEKPYECKECGKVFKWPSSLPIHMRLHTGEKPYQCKHCGKAFNCSSSLRRHVRIHTTEKQY 594

  Fly   496 VC--PHPNCNQAFTQSSNMRTHAKKCQYRPLDGLTVTSSALPV 536
            .|  .||..|: |..|::.::|.::      |.:.|.:..||:
Human   595 KCNVGHPPANE-FMCSASEKSHQER------DLIKVVNMVLPL 630

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 6/19 (32%)
COG5048 <316..502 CDD:227381 87/216 (40%)
C2H2 Zn finger 327..347 CDD:275368 7/19 (37%)
zf-C2H2 356..377 CDD:278523 10/20 (50%)
C2H2 Zn finger 357..377 CDD:275368 9/19 (47%)
zf-H2C2_2 369..394 CDD:290200 10/24 (42%)
C2H2 Zn finger 385..405 CDD:275368 8/47 (17%)
zf-H2C2_2 397..422 CDD:290200 13/52 (25%)
C2H2 Zn finger 413..433 CDD:275368 11/19 (58%)
zf-H2C2_2 426..449 CDD:290200 14/22 (64%)
zf-C2H2 439..461 CDD:278523 9/21 (43%)
C2H2 Zn finger 441..461 CDD:275368 8/19 (42%)
zf-C2H2 467..489 CDD:278523 7/21 (33%)
C2H2 Zn finger 469..489 CDD:275368 7/19 (37%)
C2H2 Zn finger 497..515 CDD:275368 6/19 (32%)
ZNF555XP_011526018.1 KRAB 6..>50 CDD:214630
KRAB 6..45 CDD:279668
C2H2 Zn finger 151..168 CDD:275368 5/25 (20%)
C2H2 Zn finger 176..196 CDD:275368 3/19 (16%)
zf-H2C2_2 188..211 CDD:290200 7/26 (27%)
COG5048 200..597 CDD:227381 126/432 (29%)
C2H2 Zn finger 204..224 CDD:275368 5/31 (16%)
zf-H2C2_2 216..239 CDD:290200 5/22 (23%)
C2H2 Zn finger 232..252 CDD:275368 4/19 (21%)
zf-H2C2_2 244..269 CDD:290200 3/24 (13%)
C2H2 Zn finger 260..280 CDD:275368 2/19 (11%)
zf-H2C2_2 273..297 CDD:290200 1/23 (4%)
C2H2 Zn finger 288..308 CDD:275368 4/22 (18%)
zf-H2C2_2 301..325 CDD:290200 8/26 (31%)
C2H2 Zn finger 316..336 CDD:275368 3/26 (12%)
zf-H2C2_2 328..353 CDD:290200 6/27 (22%)
C2H2 Zn finger 344..364 CDD:275368 4/27 (15%)
zf-H2C2_2 356..381 CDD:290200 7/29 (24%)
C2H2 Zn finger 372..392 CDD:275368 6/19 (32%)
zf-H2C2_2 384..409 CDD:290200 11/24 (46%)
C2H2 Zn finger 400..420 CDD:275368 7/19 (37%)
zf-H2C2_2 412..436 CDD:290200 11/25 (44%)
C2H2 Zn finger 428..448 CDD:275368 9/19 (47%)
zf-H2C2_2 440..464 CDD:290200 9/23 (39%)
C2H2 Zn finger 456..476 CDD:275368 8/19 (42%)
C2H2 Zn finger 484..504 CDD:275368 0/19 (0%)
zf-H2C2_2 496..520 CDD:290200 8/23 (35%)
C2H2 Zn finger 512..532 CDD:275368 11/19 (58%)
zf-H2C2_2 525..548 CDD:290200 14/22 (64%)
C2H2 Zn finger 540..560 CDD:275368 8/19 (42%)
zf-H2C2_2 556..577 CDD:290200 12/20 (60%)
C2H2 Zn finger 568..588 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.