DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG15269 and ZNF583

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:XP_005258615.1 Gene:ZNF583 / 147949 HGNCID:26427 Length:570 Species:Homo sapiens


Alignment Length:265 Identity:106/265 - (40%)
Similarity:147/265 - (55%) Gaps:11/265 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   299 KCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPECGK 362
            ||..|||||..|.:|..|::.|...: |.|.:|||.|||..|...|..:|.|.|.:  ||.||.|
Human   214 KCNDCEKVFNQSSSLTLHQRIHTGEKPYACVECGKTFSQSANLAQHKRIHTGEKPY--ECKECRK 276

  Fly   363 TFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKMLLK 427
            .|:...:|:.|.::|...|.|:|..|.|:|:|......|.|:|||.:|.:|.||||.||....|.
Human   277 AFSQNAHLAQHQRVHTGEKPYQCKECKKAFSQIAHLTQHQRVHTGERPFECIECGKAFSNGSFLA 341

  Fly   428 QHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGC 492
            ||.|.|:|||||.|:||||:|:.|..:.:|.|:|:|.:|:.|..|.|||::..||..|...|||.
Human   342 QHQRIHTGEKPYVCNVCGKAFSHRGYLIVHQRIHTGERPYECKECRKAFSQYAHLAQHQRVHTGE 406

  Fly   493 KPYVCPHPNCNQAFTQ----SSNMRTHAKKCQYRPLD-GLTVT-SSALPVPGKQQTGPPPTLAMA 551
            |||.|  ..|.:||:|    ..:.|.|..:..|..:: |...: ||:|....:..||..|.:...
Human   407 KPYEC--KVCRKAFSQIAYLDQHQRVHTGEKPYECIECGKAFSNSSSLAQHQRSHTGEKPYMCKE 469

  Fly   552 MAQTF 556
            ..:||
Human   470 CRKTF 474

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 9/19 (47%)
COG5048 <316..502 CDD:227381 81/186 (44%)
C2H2 Zn finger 327..347 CDD:275368 9/19 (47%)
zf-C2H2 356..377 CDD:278523 8/20 (40%)
C2H2 Zn finger 357..377 CDD:275368 7/19 (37%)
zf-H2C2_2 369..394 CDD:290200 9/24 (38%)
C2H2 Zn finger 385..405 CDD:275368 7/19 (37%)
zf-H2C2_2 397..422 CDD:290200 12/24 (50%)
C2H2 Zn finger 413..433 CDD:275368 11/19 (58%)
zf-H2C2_2 426..449 CDD:290200 15/22 (68%)
zf-C2H2 439..461 CDD:278523 10/21 (48%)
C2H2 Zn finger 441..461 CDD:275368 9/19 (47%)
zf-C2H2 467..489 CDD:278523 8/21 (38%)
C2H2 Zn finger 469..489 CDD:275368 8/19 (42%)
C2H2 Zn finger 497..515 CDD:275368 6/21 (29%)
ZNF583XP_005258615.1 C2H2 Zn finger 355..375 CDD:275368 9/19 (47%)
zf-H2C2_2 367..392 CDD:290200 10/24 (42%)
C2H2 Zn finger 383..403 CDD:275368 8/19 (42%)
zf-H2C2_2 395..420 CDD:290200 13/26 (50%)
C2H2 Zn finger 411..431 CDD:275368 6/21 (29%)
zf-H2C2_2 423..448 CDD:290200 4/24 (17%)
C2H2 Zn finger 439..459 CDD:275368 4/19 (21%)
zf-H2C2_2 451..476 CDD:290200 6/24 (25%)
C2H2 Zn finger 467..487 CDD:275368 2/8 (25%)
zf-H2C2_2 480..504 CDD:290200
C2H2 Zn finger 495..515 CDD:275368
zf-H2C2_2 507..532 CDD:290200
C2H2 Zn finger 523..543 CDD:275368
KRAB 7..67 CDD:214630
KRAB 7..46 CDD:279668
COG5048 210..543 CDD:227381 106/265 (40%)
C2H2 Zn finger 215..235 CDD:275368 9/19 (47%)
zf-H2C2_2 227..252 CDD:290200 9/24 (38%)
C2H2 Zn finger 243..263 CDD:275368 9/19 (47%)
zf-H2C2_2 255..280 CDD:290200 11/26 (42%)
C2H2 Zn finger 271..291 CDD:275368 7/19 (37%)
zf-H2C2_2 283..308 CDD:290200 9/24 (38%)
C2H2 Zn finger 299..319 CDD:275368 7/19 (37%)
zf-H2C2_2 311..336 CDD:290200 12/24 (50%)
C2H2 Zn finger 327..347 CDD:275368 11/19 (58%)
zf-H2C2_2 340..364 CDD:290200 16/23 (70%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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