DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15269 and ZNF664

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001191227.1 Gene:ZNF664 / 144348 HGNCID:25406 Length:261 Species:Homo sapiens


Alignment Length:229 Identity:93/229 - (40%)
Similarity:126/229 - (55%) Gaps:9/229 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   295 EISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECP 358
            |..:||..|:|.|.....|..|.:.|...: |:|.||||.||.......|..:|  |.|...:|.
Human    28 EKPHKCDKCDKGFFHISELHIHWRDHTGEKVYKCDDCGKDFSTTTKLNRHKKIH--TVEKPYKCY 90

  Fly   359 ECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRK 423
            ||||.||...:|..|:::|...|.|.|..|.:.|:......||.|:|||.||.||.||||.|...
Human    91 ECGKAFNWSSHLQIHMRVHTGEKPYVCSECGRGFSNSSNLCMHQRVHTGEKPFKCEECGKAFRHT 155

  Fly   424 MLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNY 488
            ..|..|.|.|:|||||:|..|||:|:..|::.:|.|:|:|.||:.|..|.|||::...|..|...
Human   156 SSLCMHQRVHTGEKPYKCYECGKAFSQSSSLCIHQRVHTGEKPYRCCGCGKAFSQSSSLCIHQRV 220

  Fly   489 HTGCKPYVCPHPNCNQAFTQSSNM----RTHAKK 518
            |||.||:.|  ..|.:||:||:::    |.|.|:
Human   221 HTGEKPFKC--DECGKAFSQSTSLCIHQRVHTKE 252

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 6/19 (32%)
COG5048 <316..502 CDD:227381 78/186 (42%)
C2H2 Zn finger 327..347 CDD:275368 8/19 (42%)
zf-C2H2 356..377 CDD:278523 9/20 (45%)
C2H2 Zn finger 357..377 CDD:275368 9/19 (47%)
zf-H2C2_2 369..394 CDD:290200 8/24 (33%)
C2H2 Zn finger 385..405 CDD:275368 6/19 (32%)
zf-H2C2_2 397..422 CDD:290200 15/24 (63%)
C2H2 Zn finger 413..433 CDD:275368 9/19 (47%)
zf-H2C2_2 426..449 CDD:290200 13/22 (59%)
zf-C2H2 439..461 CDD:278523 9/21 (43%)
C2H2 Zn finger 441..461 CDD:275368 8/19 (42%)
zf-C2H2 467..489 CDD:278523 7/21 (33%)
C2H2 Zn finger 469..489 CDD:275368 7/19 (37%)
C2H2 Zn finger 497..515 CDD:275368 7/21 (33%)
ZNF664NP_001191227.1 C2H2 Zn finger 5..25 CDD:275368
C2H2 Zn finger 33..53 CDD:275368 6/19 (32%)
C2H2 Zn finger 61..81 CDD:275368 8/19 (42%)
zf-H2C2_2 74..97 CDD:404364 9/24 (38%)
C2H2 Zn finger 89..109 CDD:275368 9/19 (47%)
COG5048 <94..256 CDD:227381 68/161 (42%)
C2H2 Zn finger 117..137 CDD:275368 6/19 (32%)
C2H2 Zn finger 145..165 CDD:275368 9/19 (47%)
C2H2 Zn finger 173..193 CDD:275368 8/19 (42%)
C2H2 Zn finger 201..221 CDD:275368 7/19 (37%)
C2H2 Zn finger 229..249 CDD:275368 7/21 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24384
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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