DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15269 and Egr2

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_001360912.1 Gene:Egr2 / 13654 MGIID:95296 Length:483 Species:Mus musculus


Alignment Length:525 Identity:124/525 - (23%)
Similarity:174/525 - (33%) Gaps:193/525 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 VQNLGAGAQLPPAQVTDFSISKILG---KERKSAQDTSTNI--------LDLSKSSSNS-IRSPQ 73
            |::|.|      :.||.|...::.|   :....|.|...||        |||...||.: |.:|:
Mouse    41 VEDLAA------SSVTIFPNGELGGPFDQMNGVAGDGMINIDMTGEKRPLDLPYPSSFAPISAPR 99

  Fly    74 -----ALGGLAIPSTPYASGAYSMLPPDLVAMANATKFYAQFFPHLLPAYAAAAAAAGLSTPP-- 131
                 .:|..:|  .|...|| |..|..::.:.:     |.....:.|..:..|:::..|..|  
Mouse   100 NQTFTYMGKFSI--DPQYPGA-SCYPEGIINIVS-----AGILQGVTPPASTTASSSVTSASPNP 156

  Fly   132 --TSPY------QTHQHQQHLPNQQKRFFAPYVINGSVPPPPPLQQQQQPLIRTKSTACTRPDCP 188
              |.|.      ||.....||       ::|       |||||           ..:.||.    
Mouse   157 LATGPLGVCTMSQTQPELDHL-------YSP-------PPPPP-----------PYSGCTG---- 192

  Fly   189 ECLDYYQRLQTGGYKQTAPLISPAASSVSS-------STGSIRPVRD-----LIMSATG------ 235
               |.||       ..:|.|..|:.:|.||       |..|.:|..|     :|....|      
Mouse   193 ---DLYQ-------DPSAFLSPPSTTSTSSLAYQPPPSYPSPKPAMDPGLIPMIPDYPGFFPSPC 247

  Fly   236 -----GAASTN-----------------ISLTTVTNLSLNSVQATAVGMMPKMTGGLITTAV-GS 277
                 |||..:                 ..|:|:.|.:|....|...|  |..:||.....: ||
Mouse   248 QRDPHGAAGPDRKPFPCPLDSLRVPPPLTPLSTIRNFTLGGPGAGVTG--PGASGGGEGPRLPGS 310

  Fly   278 NSGAIGGIGGYNATSAEEISYKCRICEKVFGCSETLQAHEKTHKSPRYECADCGKGFSQLRNYKY 342
            .|.|:                             |...:...|...|          ..||..||
Mouse   311 GSAAV-----------------------------TATPYNPHHLPLR----------PILRPRKY 336

  Fly   343 HLSVHRGTKEFAAECPECGKTFNDKGYLSSHLKIHRNRKEYECPY--CPKSFNQRVAFNMHVRIH 405
               .:|.:|....|.|                        |.||.  |.:.|::......|:|||
Mouse   337 ---PNRPSKTPVHERP------------------------YPCPAEGCDRRFSRSDELTRHIRIH 374

  Fly   406 TGVKPHKCNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIK--PFS 468
            ||.||.:|..|.:.|||...|..|:|||:||||:.|..||:.||.......|.::|...|  ..|
Mouse   375 TGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGRKFARSDERKRHTKIHLRQKERKSS 439

  Fly   469 CPLCP 473
            .|..|
Mouse   440 APSAP 444

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 1/19 (5%)
COG5048 <316..502 CDD:227381 48/162 (30%)
C2H2 Zn finger 327..347 CDD:275368 4/19 (21%)
zf-C2H2 356..377 CDD:278523 2/20 (10%)
C2H2 Zn finger 357..377 CDD:275368 1/19 (5%)
zf-H2C2_2 369..394 CDD:290200 5/26 (19%)
C2H2 Zn finger 385..405 CDD:275368 6/21 (29%)
zf-H2C2_2 397..422 CDD:290200 11/24 (46%)
C2H2 Zn finger 413..433 CDD:275368 8/19 (42%)
zf-H2C2_2 426..449 CDD:290200 12/22 (55%)
zf-C2H2 439..461 CDD:278523 6/21 (29%)
C2H2 Zn finger 441..461 CDD:275368 6/19 (32%)
zf-C2H2 467..489 CDD:278523 3/7 (43%)
C2H2 Zn finger 469..489 CDD:275368 2/5 (40%)
C2H2 Zn finger 497..515 CDD:275368
Egr2NP_001360912.1 DUF3446 107..179 CDD:371803 18/86 (21%)
zf-C2H2 350..374 CDD:333835 7/23 (30%)
C2H2 Zn finger 352..374 CDD:275368 6/21 (29%)
COG5048 378..>434 CDD:227381 23/55 (42%)
C2H2 Zn finger 382..402 CDD:275368 8/19 (42%)
C2H2 Zn finger 410..430 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.