DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and AgaP_AGAP005938

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_315968.4	Gene:	AgaP_AGAP005938 / 1276605	VectorBaseID:	AGAP005938	Length:	512	Species:	Anopheles gambiae

Alignment Length:	234	Identity:	64/234 - (27%)
Similarity:	114/234 - (48%)	Gaps:	20/234 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 SYKCRICEKVFGCSETLQAH-EKTHKSP---RYECADCGKGFSQLRNYKYHLSVHRGTKEFAAEC 357
            :::|..|.:.:..|:.|:.| ::.|.:.   .:.|..|.|.|..    :.||:.|......:..|
Mosquito   268 AFRCEQCARSYSSSKVLKEHLKEVHAAAAERSFPCETCRKAFVS----RAHLNAHVMVAHGSVSC 328

  Fly   358 PECGKTFNDKGYLSSHL-KIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPH---KCNECGK 418
            |:|.|....:|.|..|| .:|...:::.|..|.:.|..:.:|:.|.::|.|.:..   :|:.|..
Mosquito   329 PQCDKVLASQGSLRKHLVAVHGEGEKHVCEVCARVFRSKQSFDTHRKVHAGSRLESKVQCDLCQA 393

  Fly   419 RFSRKMLLKQHM-RTHSGE--KPYQCSVCGKSFADRSNMTLH-HRLHSGIKPFSCPLCPKAFTKK 479
            ....|..|.:|: |.||.:  :|..|:.|||||.:::.:..| .|.|...: |.|..|.|.|.:.
Mosquito   394 WLMDKYCLTKHVRRMHSDQDGEPVACAECGKSFRNQNALNGHMWRAHQESR-FECERCHKRFKRP 457

  Fly   480 HHLKTHLN-YHTGCKPYVCPHPNCNQAFTQSSNMRTHAK 517
            ||::.|:. :|||.:.|.|.:  |::.|...:...:|.|
Mosquito   458 HHMREHIAIHHTGDELYGCKY--CSERFNTRNKQLSHRK 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	5/20 (25%)
		COG5048	<316..502	CDD:227381	56/198 (28%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		zf-C2H2	356..377	CDD:278523	8/21 (38%)
		C2H2 Zn finger	357..377	CDD:275368	8/20 (40%)
		zf-H2C2_2	369..394	CDD:290200	7/25 (28%)
		C2H2 Zn finger	385..405	CDD:275368	5/19 (26%)
		zf-H2C2_2	397..422	CDD:290200	6/27 (22%)
		C2H2 Zn finger	413..433	CDD:275368	6/20 (30%)
		zf-H2C2_2	426..449	CDD:290200	11/25 (44%)
		zf-C2H2	439..461	CDD:278523	8/22 (36%)
		C2H2 Zn finger	441..461	CDD:275368	8/20 (40%)
		zf-C2H2	467..489	CDD:278523	8/22 (36%)
		C2H2 Zn finger	469..489	CDD:275368	7/20 (35%)
		C2H2 Zn finger	497..515	CDD:275368	3/17 (18%)
AgaP_AGAP005938	XP_315968.4	zf-AD	7..64	CDD:214871
		C2H2 Zn finger	271..292	CDD:275368	5/20 (25%)
		C2H2 Zn finger	302..344	CDD:275368	13/45 (29%)
		C2H2 Zn finger	357..377	CDD:275368	5/19 (26%)
		C2H2 Zn finger	419..440	CDD:275368	8/20 (40%)
		C2H2 Zn finger	447..467	CDD:275368	7/19 (37%)
		C2H2 Zn finger	476..495	CDD:275368	5/21 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910