DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15269 and AgaP_AGAP006791

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_308956.4	Gene:	AgaP_AGAP006791 / 1270274	VectorBaseID:	AGAP006791	Length:	797	Species:	Anopheles gambiae

Alignment Length:	624	Identity:	161/624 - (25%)
Similarity:	223/624 - (35%)	Gaps:	196/624 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SPSPARTSPTNGVQNLGAGAQLPPAQVTDFSISKILGKERKSAQDTSTNIL--------DLSKSS 65
            :||.|..||           |..|||           |:..:...|||...        |:.:..
Mosquito   232 APSAATDSP-----------QRSPAQ-----------KKSLAMCFTSTGTALSLPPKKKDIYRPY 274

  Fly    66 SNSIRSPQALGGLAIPSTPYASGAYSMLPPDLVAMANATKFYAQFFPHLLPAYAAAAAAAGLSTP 130
            |...|.|:....|.||:......|:::|  ||.|   :|.|                      .|
Mosquito   275 SLDDRPPRPSYELRIPAEEDLHAAHAIL--DLSA---STAF----------------------LP 312

  Fly   131 PTSPYQ-THQHQQHLPNQQKRFFAPYVINGSVPPPP--------PLQ--------QQQQPLIRTK 178
            |.:|:| ..|.|...|:.|:...||.|:  .|||.|        |||        ||||.|.:|.
Mosquito   313 PPAPHQLLAQQQPPSPSVQQSTPAPVVL--VVPPKPAIAEPDRRPLQAHPQQQPPQQQQQLHQTA 375

  Fly   179 STACTRPDCPECLDYYQRLQTGGYKQTAPLISPAASSVSSSTGSIRPVRDLIMSATGGAASTNIS 243
            |        |..|               ||.||.|::|..:.||  |.::      ....|||
Mosquito   376 S--------PPPL---------------PLQSPPATTVPHALGS--PEQN------ENRNSTN-- 407

  Fly   244 LTTVTNLSLNSVQATAVGMMPKMTGGLITTAVGSNSGAIGGIGGYNATSAEEISYKCRICEKVF- 307
                   :|....|.....|...:..|..:|..|:|      .|.|.:.....:|     |..|
Mosquito   408 -------TLPGYAAHDATSMDSSSDELGQSAESSDS------EGRNGSKTVAYTY-----EAFFV 454

  Fly   308 --GCSETLQAHEKT--HKSPRYECADCGKGFSQLRNYKYHLSVHRG-TKEFAAECPECGKTFNDK 367
              |.|:...|..||  ....:|.|.:|||.::...|...|...||. ..:.|.:|..|||.:...
Mosquito   455 SDGRSKKKMADPKTALENKAKYTCTECGKQYATSSNLSRHKQTHRSLDSQSAKKCHTCGKAYVSM 519

  Fly   368 GYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKMLLKQHMRT 432
            ..|:.|:..|:                              ..|.|..|||.|||..||:.|:|:
Mosquito   520 PALAMHVLTHK------------------------------LSHSCGVCGKLFSRPWLLQGHLRS 554

  Fly   433 HSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGC-KPYV 496
            |:|||||.|:.|||:||||||:..|.:.||..|.:.|..|.|.|..|.:|..||  .:.| |...
Mosquito   555 HTGEKPYGCAHCGKAFADRSNLRAHMQTHSIDKNYQCGRCHKTFALKSYLNKHL--ESACFKEDG 617

  Fly   497 CPHPNCNQAFTQSSNMRTHAKKCQYRPLDGLTVTS-SALPVPGKQQTGPPPTLAM---------- 550
            .|........:..|             |||.::.. .:.|:..::|   |..|..
Mosquito   618 APQSPLMSPMSPGS-------------LDGSSLDDLRSTPLSERRQ---PVALKRERNVDIEGDE 666

  Fly   551 ---AMAQTFQMPPPPGVLTPGSGPSQPPSQQTLLSNLRT 586
               |||....:.|.|..||...|.........::.||::
Mosquito   667 SDDAMACPSPLSPVPHHLTISPGAPNGTGSIFVMKNLQS 705

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	7/24 (29%)
		COG5048	<316..502	CDD:227381	62/189 (33%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		zf-C2H2	356..377	CDD:278523	6/20 (30%)
		C2H2 Zn finger	357..377	CDD:275368	6/19 (32%)
		zf-H2C2_2	369..394	CDD:290200	3/24 (13%)
		C2H2 Zn finger	385..405	CDD:275368	0/19 (0%)
		zf-H2C2_2	397..422	CDD:290200	6/24 (25%)
		C2H2 Zn finger	413..433	CDD:275368	11/19 (58%)
		zf-H2C2_2	426..449	CDD:290200	13/22 (59%)
		zf-C2H2	439..461	CDD:278523	12/21 (57%)
		C2H2 Zn finger	441..461	CDD:275368	11/19 (58%)
		zf-C2H2	467..489	CDD:278523	8/21 (38%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		C2H2 Zn finger	497..515	CDD:275368	2/17 (12%)
AgaP_AGAP006791	XP_308956.4	zf-C2H2	476..498	CDD:278523	7/21 (33%)
		C2H2 Zn finger	478..498	CDD:275368	6/19 (32%)
		C2H2 Zn finger	509..526	CDD:275371	5/16 (31%)
		C2H2 Zn finger	535..555	CDD:275368	11/19 (58%)
		zf-H2C2_2	548..571	CDD:290200	13/22 (59%)
		C2H2 Zn finger	563..583	CDD:275368	11/19 (58%)
		zf-C2H2	563..583	CDD:278523	11/19 (58%)
		zf-H2C2_2	575..599	CDD:290200	8/23 (35%)
		C2H2 Zn finger	591..608	CDD:275368	6/16 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910