DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15269 and AgaP_AGAP007514

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_308362.4	Gene:	AgaP_AGAP007514 / 1269713	VectorBaseID:	AGAP007514	Length:	525	Species:	Anopheles gambiae

Alignment Length:	268	Identity:	73/268 - (27%)
Similarity:	120/268 - (44%)	Gaps:	53/268 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   294 EEISYKCRICEKVFGCSETLQAHEKTHKSP-RYECADCGKGFSQLRNYKYHLSVHRGTKEFAAEC 357
            :::..||.:||......:||..|...|::| :|.|..||:   :.:|.|.|:......::|.  |
Mosquito   249 DKVYVKCPVCEMKMRTKQTLLQHMDWHENPEKYRCELCGE---KHQNMKEHIQNKHQERQFC--C 308

  Fly   358 PECGKTFNDKGYLSSHLK----------------------------IHRNRKEYECPYCPKSFNQ 394
            ..|||.|..|..|:.|:|                            :|..|  :.|.:|||:||.
Mosquito   309 DVCGKKFPFKKRLTVHMKKMHVEKDIICDQCQKPFTKYTIEDHKRSVHSAR--FVCEHCPKTFNS 371

  Fly   395 RVAFNMHVRIH-------TGVKPHKCNECGKRFSRKMLLKQHMR-THSGEKPYQCSVCGKSFADR 451
            |.....|:..|       |.|   .|..||:....|.:|.:|:: .|:.:....|..|||:|..:
Mosquito   372 RFRLLQHMEEHDESLRNSTSV---PCTICGQVMRDKYILTRHIKLMHTVQPAVSCETCGKTFKCK 433

  Fly   452 SNMTLHHRLHSGIKP---FSCPLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMR 513
            .|::: |..:..::|   :.|.:|.|.|.:|:.||.|::.|||...|:|..  |.:.|.|.:::.
Mosquito   434 RNLSV-HMTNVCMEPTRLYPCTICGKEFRRKNKLKEHMSTHTGKPLYMCSF--CPETFRQDTHLY 495

  Fly   514 THAKKCQY 521
            .|.|...|
Mosquito   496 HHRKNAHY 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	6/19 (32%)
		COG5048	<316..502	CDD:227381	61/225 (27%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		zf-C2H2	356..377	CDD:278523	9/48 (19%)
		C2H2 Zn finger	357..377	CDD:275368	9/47 (19%)
		zf-H2C2_2	369..394	CDD:290200	10/52 (19%)
		C2H2 Zn finger	385..405	CDD:275368	8/19 (42%)
		zf-H2C2_2	397..422	CDD:290200	7/31 (23%)
		C2H2 Zn finger	413..433	CDD:275368	6/20 (30%)
		zf-H2C2_2	426..449	CDD:290200	7/23 (30%)
		zf-C2H2	439..461	CDD:278523	7/21 (33%)
		C2H2 Zn finger	441..461	CDD:275368	7/19 (37%)
		zf-C2H2	467..489	CDD:278523	8/21 (38%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		C2H2 Zn finger	497..515	CDD:275368	4/17 (24%)
AgaP_AGAP007514	XP_308362.4	zf-AD	6..74	CDD:214871
		C2H2 Zn finger	255..275	CDD:275368	6/19 (32%)
		C2H2 Zn finger	283..300	CDD:275368	6/19 (32%)
		C2H2 Zn finger	308..328	CDD:275368	9/19 (47%)
		C2H2 Zn finger	336..356	CDD:275368	0/19 (0%)
		C2H2 Zn finger	362..382	CDD:275368	8/19 (42%)
		C2H2 Zn finger	394..415	CDD:275368	6/20 (30%)
		C2H2 Zn finger	423..445	CDD:275368	7/22 (32%)
		C2H2 Zn finger	453..473	CDD:275368	8/19 (42%)
		C2H2 Zn finger	481..499	CDD:275368	5/19 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910