DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and znf408

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	NP_001315204.1	Gene:	znf408 / 108004540	ZFINID:	ZDB-GENE-130530-589	Length:	764	Species:	Danio rerio

Alignment Length:	278	Identity:	92/278 - (33%)
Similarity:	142/278 - (51%)	Gaps:	32/278 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   298 YKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKE-----FAAE 356
            :||..|:|.:|....|:.|:..|...: :.|..|||.|::..:.:.|..:|| |||     ...:
Zfish   378 FKCEQCDKSYGLKRDLKEHQVLHSGEKPFVCDICGKAFARRPSLRVHREIHR-TKEPDYQALKVK 441

  Fly   357 CPECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFS 421
            ||||.|...:.|.|.:|:::|...:.:.||:|.|.|.||.....|:|||||.||::|:.|..|||
Zfish   442 CPECDKELANSGSLRNHMRLHTGERPHICPHCNKCFRQRGNLQGHMRIHTGEKPYRCDHCDLRFS 506

  Fly   422 RKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHL 486
            :...|::|:.:|:|| .|.|.||||:..|...:..|.|||:|.:|:.|..|.|.:|....|:.||
Zfish   507 QVPELRRHLISHTGE-VYLCPVCGKALRDPHTLRAHERLHTGDRPYKCEQCGKGYTMATKLRRHL 570

  Fly   487 NYHTGCKPYVCPHPNCNQAFTQSSNMRTHAKKCQYRPLDGLTVTSSALPVPG-------KQQTGP 544
            ..|...|.:||  ..|...::...:::.|.:  .::|..|     .|||..|       |::..|
Zfish   571 KSHLEEKQHVC--QVCGAKYSMMQSLQRHLQ--LHQPDSG-----HALPTRGRPKRLGQKEEEEP 626

  Fly   545 PPT--------LAMAMAQ 554
            ..|        .|:|.||
Zfish   627 GRTESSGLEAGQAVACAQ 644

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	6/19 (32%)
		COG5048	<316..502	CDD:227381	71/191 (37%)
		C2H2 Zn finger	327..347	CDD:275368	6/19 (32%)
		zf-C2H2	356..377	CDD:278523	8/20 (40%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		zf-H2C2_2	369..394	CDD:290200	8/24 (33%)
		C2H2 Zn finger	385..405	CDD:275368	9/19 (47%)
		zf-H2C2_2	397..422	CDD:290200	12/24 (50%)
		C2H2 Zn finger	413..433	CDD:275368	7/19 (37%)
		zf-H2C2_2	426..449	CDD:290200	11/22 (50%)
		zf-C2H2	439..461	CDD:278523	9/21 (43%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		zf-C2H2	467..489	CDD:278523	7/21 (33%)
		C2H2 Zn finger	469..489	CDD:275368	7/19 (37%)
		C2H2 Zn finger	497..515	CDD:275368	2/17 (12%)
znf408	NP_001315204.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24384
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100