DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG15269 and ZNF460

DIOPT Version :9

Sequence 1:NP_609739.2 Gene:CG15269 / 34887 FlyBaseID:FBgn0028878 Length:587 Species:Drosophila melanogaster
Sequence 2:NP_006626.3 Gene:ZNF460 / 10794 HGNCID:21628 Length:562 Species:Homo sapiens


Alignment Length:247 Identity:97/247 - (39%)
Similarity:125/247 - (50%) Gaps:33/247 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   298 YKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPECG 361
            |.|..|.|.||.|:.|..|...|...: |:|.:|||.|::..:...|...|.|.|.|.  |.|||
Human   196 YDCPECGKAFGKSKHLLQHHIIHTGEKPYKCLECGKDFNRRSHLTRHQRTHNGDKPFV--CSECG 258

  Fly   362 KTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVR----------------------- 403
            :|||...:|:.|.::|...|.:.|..|.|:|..|..|.:|.:                       
Human   259 RTFNRGSHLTRHQRVHSGEKPFVCNECGKAFTYRSNFVLHNKSHNEKKPFACSECGKGFYESTAL 323

  Fly   404 -----IHTGVKPHKCNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSG 463
                 ||||.:|.||.||||.|:.:..||||.|.|:||||:.||.|||:|...|...||.|.|:|
Human   324 IQHFIIHTGERPFKCLECGKAFNCRSHLKQHERIHTGEKPFVCSQCGKAFTHYSTYVLHERAHTG 388

  Fly   464 IKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTH 515
            .|||.|..|.|||:.:..|..|.|.|||.|||.|  ..|.:|||:.|.:..|
Human   389 EKPFECKECGKAFSIRKDLIRHFNIHTGEKPYEC--LQCGKAFTRMSGLTRH 438

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG15269NP_609739.2 C2H2 Zn finger 300..320 CDD:275368 8/19 (42%)
COG5048 <316..502 CDD:227381 83/214 (39%)
C2H2 Zn finger 327..347 CDD:275368 6/19 (32%)
zf-C2H2 356..377 CDD:278523 9/20 (45%)
C2H2 Zn finger 357..377 CDD:275368 9/19 (47%)
zf-H2C2_2 369..394 CDD:290200 8/24 (33%)
C2H2 Zn finger 385..405 CDD:275368 7/47 (15%)
zf-H2C2_2 397..422 CDD:290200 14/52 (27%)
C2H2 Zn finger 413..433 CDD:275368 11/19 (58%)
zf-H2C2_2 426..449 CDD:290200 15/22 (68%)
zf-C2H2 439..461 CDD:278523 10/21 (48%)
C2H2 Zn finger 441..461 CDD:275368 10/19 (53%)
zf-C2H2 467..489 CDD:278523 9/21 (43%)
C2H2 Zn finger 469..489 CDD:275368 8/19 (42%)
C2H2 Zn finger 497..515 CDD:275368 6/17 (35%)
ZNF460NP_006626.3 KRAB 12..53 CDD:307490
C2H2 Zn finger 198..218 CDD:275368 8/19 (42%)
COG5048 222..552 CDD:227381 87/221 (39%)
C2H2 Zn finger 226..246 CDD:275368 6/19 (32%)
C2H2 Zn finger 254..274 CDD:275368 9/19 (47%)
C2H2 Zn finger 282..302 CDD:275368 7/19 (37%)
C2H2 Zn finger 310..330 CDD:275368 0/19 (0%)
C2H2 Zn finger 338..358 CDD:275368 11/19 (58%)
C2H2 Zn finger 366..386 CDD:275368 10/19 (53%)
C2H2 Zn finger 394..414 CDD:275368 8/19 (42%)
C2H2 Zn finger 422..442 CDD:275368 7/19 (37%)
C2H2 Zn finger 450..470 CDD:275368
C2H2 Zn finger 478..498 CDD:275368
C2H2 Zn finger 506..526 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24384
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

Return to query results.
Submit another query.