DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and znf977

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_021331166.1	Gene:	znf977 / 103910561	ZFINID:	ZDB-GENE-110913-138	Length:	765	Species:	Danio rerio

Alignment Length:	349	Identity:	119/349 - (34%)
Similarity:	166/349 - (47%)	Gaps:	49/349 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 LIRT--KSTACTRP----DCPECLDYYQRLQTGGYKQTAPLISPAASSVSSSTGSIRPVRDLIMS 232
            :|.|  |...||:.    .|...|:.:.|:.||....|.   :....|.:.|:
Zfish    30 MIHTGEKPFTCTQCGKSFSCSSYLNLHMRIHTGEQPFTC---NQCGKSFNRSS------------ 79

  Fly   233 ATGGAASTNISLTTVTNLSLNSVQATAVGMMPKMTGGLITTAVGSNSGAIGGIGGYNATSAEEIS 297
                              :||.......|..|     .|.|..|.:......:..:......|..
Zfish    80 ------------------TLNKHMKIHTGEKP-----FICTQCGRSFNRSSHLNDHMKIHTGEKP 121

  Fly   298 YKCRICEKVFGCSETLQAHEKTH-KSPRYECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPECG 361
            :.|..|.|.|..|..|..|.:.| :...:.|..|||.|:|..:...|:.:|.|.|.|.  |.:||
Zfish   122 FTCTQCGKSFSQSSYLNKHMRIHTREKPFTCTQCGKSFNQSSHLNKHMKIHTGEKPFT--CTQCG 184

  Fly   362 KTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKMLL 426
            |:||...:|:||:|||...|.:.|..|.|||.|..:.|.|:|.|||.||..|.:|||.||:...|
Zfish   185 KSFNQLSHLNSHMKIHTGEKPFTCTQCGKSFRQSSSLNRHMRTHTGEKPFTCTQCGKSFSQSSSL 249

  Fly   427 KQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTG 491
            ..|||.|:||||:.|:.|||||:..|::.||.|:|:|.|||:||.|.|:|.:..||..|:..|||
Zfish   250 NLHMRIHTGEKPFTCTQCGKSFSQSSSLNLHVRIHTGEKPFTCPHCGKSFNQSSHLNCHMKIHTG 314

  Fly   492 CKPYVCPHPNCNQAFTQSSNMRTH 515
            .||:.|  |.|.::|:||||:..|
Zfish   315 EKPFTC--PQCGKSFSQSSNLNCH 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	7/19 (37%)
		COG5048	<316..502	CDD:227381	85/186 (46%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		zf-C2H2	356..377	CDD:278523	10/20 (50%)
		C2H2 Zn finger	357..377	CDD:275368	10/19 (53%)
		zf-H2C2_2	369..394	CDD:290200	12/24 (50%)
		C2H2 Zn finger	385..405	CDD:275368	9/19 (47%)
		zf-H2C2_2	397..422	CDD:290200	13/24 (54%)
		C2H2 Zn finger	413..433	CDD:275368	10/19 (53%)
		zf-H2C2_2	426..449	CDD:290200	14/22 (64%)
		zf-C2H2	439..461	CDD:278523	10/21 (48%)
		C2H2 Zn finger	441..461	CDD:275368	10/19 (53%)
		zf-C2H2	467..489	CDD:278523	9/21 (43%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		C2H2 Zn finger	497..515	CDD:275368	8/17 (47%)
znf977	XP_021331166.1	COG5048	8..415	CDD:227381	119/349 (34%)
		C2H2 Zn finger	12..32	CDD:275368	0/1 (0%)
		C2H2 Zn finger	40..60	CDD:275368	5/19 (26%)
		C2H2 Zn finger	68..88	CDD:275368	4/52 (8%)
		C2H2 Zn finger	96..116	CDD:275368	2/19 (11%)
		C2H2 Zn finger	124..144	CDD:275368	7/19 (37%)
		C2H2 Zn finger	152..172	CDD:275368	7/19 (37%)
		C2H2 Zn finger	180..200	CDD:275368	10/19 (53%)
		C2H2 Zn finger	208..228	CDD:275368	9/19 (47%)
		C2H2 Zn finger	236..256	CDD:275368	10/19 (53%)
		C2H2 Zn finger	264..284	CDD:275368	10/19 (53%)
		C2H2 Zn finger	292..312	CDD:275368	8/19 (42%)
		C2H2 Zn finger	320..340	CDD:275368	9/19 (47%)
		COG5048	343..756	CDD:227381
		C2H2 Zn finger	348..368	CDD:275368
		C2H2 Zn finger	376..396	CDD:275368
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	460..480	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	516..536	CDD:275368
		C2H2 Zn finger	544..564	CDD:275368
		C2H2 Zn finger	572..592	CDD:275368
		C2H2 Zn finger	600..620	CDD:275368
		C2H2 Zn finger	628..648	CDD:275368
		C2H2 Zn finger	656..676	CDD:275368
		C2H2 Zn finger	684..704	CDD:275368
		C2H2 Zn finger	712..732	CDD:275368
		C2H2 Zn finger	740..760	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910