DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and LOC103691005

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_038956093.1	Gene:	LOC103691005 / 103691005	RGDID:	9163837	Length:	764	Species:	Rattus norvegicus

Alignment Length:	448	Identity:	139/448 - (31%)
Similarity:	195/448 - (43%)	Gaps:	98/448 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 SPYQTHQ--HQQHLPNQQK---RFFAPYVINGSVPPPPPLQQQQQPLIRTKSTACTRPDCPEC-- 190
            |..::||  |....|.:.|   :.||.|         |..:..|:  |.|....|:   ||||
  Rat   275 SALKSHQKLHTGEKPYKCKECDKSFAHY---------PNFRTHQK--IHTSEEHCS---CPECGR 325

  Fly   191 ----LDYYQ---RLQTG-----------GYKQTAPL------------------------ISPAA 213
                |.:::   ||.||           .:...|.|                        :|...
  Rat   326 EFHQLSHFRKHYRLHTGEKPYKCNECGRSFTHYASLRWHQKTHSPEMHHECKECGKAFIELSHLK 390

  Fly   214 SSVSSSTGSIRPVRDLIMSATGGAASTNISLTTVTNLSLNSVQATAVGMMPKMTGGLITTAVGSN 278
            ......||. :|.:..|...         |.||.|.|..:  |....|..|........:.:.|:
  Rat   391 RHYRIHTGE-KPYKCEICDK---------SFTTTTTLKTH--QKIHTGEKPYKCRECDKSFIHSS 443

  Fly   279 SGAIGGIGGYNATSAEEISYKCRICEKVFGCSETLQAHEKTHKSPR-YECADCGKGFSQ---LRN 339
            .     :..:.:....|..|||:.|:|.|..:.||:.|||:|...: |:|.:|.|.|:|   |||
  Rat   444 H-----LRRHQSIHTGERPYKCKECDKSFRENSTLREHEKSHTEEKTYKCRECDKSFTQRAYLRN 503

  Fly   340 YKYHLSVHRGTKEFAAECPECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRI 404
              :|..||.|.:.:  ||.||||:|.....|..|..||..:|.|:|..|.|||........|.::
  Rat   504 --HHNRVHTGERPY--ECKECGKSFITCSTLKIHQTIHTGKKPYKCMECEKSFTHNSYLRTHQKV 564

  Fly   405 HTGVKPHKCNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSC 469
            |||.:|:||.||.|.|:....||.|...|||||||:|..|.|||...|::..|.|:|:|.:|:.|
  Rat   565 HTGERPYKCKECDKSFTSCSTLKAHQNIHSGEKPYKCIECDKSFTQASHLRTHQRVHTGERPYRC 629

  Fly   470 PLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRTHAK--------KC 519
            ..|.|:||:..||:.|...|:|.|||.|  .:|:.:|.|.||:|.|.|        ||
  Rat   630 IECDKSFTRYSHLREHQKIHSGEKPYKC--RDCDISFNQISNLRRHQKLHTGEKPYKC 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	9/19 (47%)
		COG5048	<316..502	CDD:227381	81/189 (43%)
		C2H2 Zn finger	327..347	CDD:275368	9/22 (41%)
		zf-C2H2	356..377	CDD:278523	9/20 (45%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		zf-H2C2_2	369..394	CDD:290200	11/24 (46%)
		C2H2 Zn finger	385..405	CDD:275368	6/19 (32%)
		zf-H2C2_2	397..422	CDD:290200	11/24 (46%)
		C2H2 Zn finger	413..433	CDD:275368	8/19 (42%)
		zf-H2C2_2	426..449	CDD:290200	14/22 (64%)
		zf-C2H2	439..461	CDD:278523	9/21 (43%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		zf-C2H2	467..489	CDD:278523	8/21 (38%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		C2H2 Zn finger	497..515	CDD:275368	7/17 (41%)
LOC103691005	XP_038956093.1	KRAB	33..73	CDD:396083
		COG5048	140..526	CDD:227381	72/285 (25%)
		C2H2 Zn finger	208..228	CDD:275368
		C2H2 Zn finger	236..256	CDD:275368
		C2H2 Zn finger	264..284	CDD:275368	3/8 (38%)
		C2H2 Zn finger	292..312	CDD:275368	6/30 (20%)
		C2H2 Zn finger	348..368	CDD:275368	2/19 (11%)
		COG5048	374..734	CDD:227381	114/335 (34%)
		C2H2 Zn finger	376..396	CDD:275368	1/19 (5%)
		C2H2 Zn finger	404..424	CDD:275368	7/30 (23%)
		C2H2 Zn finger	432..452	CDD:275368	1/24 (4%)
		C2H2 Zn finger	460..480	CDD:275368	9/19 (47%)
		C2H2 Zn finger	488..509	CDD:275368	9/22 (41%)
		C2H2 Zn finger	517..537	CDD:275368	8/19 (42%)
		C2H2 Zn finger	545..565	CDD:275368	6/19 (32%)
		C2H2 Zn finger	573..593	CDD:275368	8/19 (42%)
		C2H2 Zn finger	601..621	CDD:275368	8/19 (42%)
		C2H2 Zn finger	629..649	CDD:275368	8/19 (42%)
		C2H2 Zn finger	657..677	CDD:275368	9/21 (43%)
		C2H2 Zn finger	685..705	CDD:275368	1/1 (100%)
		C2H2 Zn finger	713..733	CDD:275368
		C2H2 Zn finger	741..761	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910