DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15269 and LOC100485704

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_017950222.2	Gene:	LOC100485704 / 100485704	-ID:	-	Length:	959	Species:	Xenopus tropicalis

Alignment Length:	677	Identity:	178/677 - (26%)
Similarity:	237/677 - (35%)	Gaps:	215/677 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PARTSPTNGVQNLGAGAQLPPAQVTDFSISKI---LGKERKSAQDTSTNILDLSKSSSN------ 67
            |.||.| ||.....||       :|.|.:...   .|||.|     |..:::..|:..|
Frog   131 PIRTGP-NGESRRNAG-------ITVFRLIPCGTGKGKENK-----SNRLIEQPKNLKNYKQREA 182

  Fly    68 ----SIRSPQALGG----LAIPST---PYAS-------GAYSMLPPDLVAMANATKFYAQF---- 110
                .|:...|:.|    ..||.:   |..|       .|.|.:.|.|     .||...:|
Frog   183 EMDSHIKRTLAIKGEKTSPLIPESHKVPAQSTKRSEFCSAQSSIQPFL-----CTKCERRFRSNE 242

  Fly   111 ----------------------FPHLLPAYAAAAAAAGLSTPPTSPYQ--THQHQQ-HLPNQQKR 150
                                  |.|.:...|......|....|...|:  .||||| |...:
Frog   243 DLLSHKRIHTGRPFVCAVCGKCFSHRIILQAHQWLHTGEKPFPCFLYKRGLHQHQQIHQKGK--- 304

  Fly   151 FFAPYVINGSVPPPPPLQQQQQPLIRTKSTACTRP-DCPEC---------LDYYQRLQTGGYKQT 205
               |||.:.........|...|.|:   ..|..:| .|.||         |..:|.:.||
Frog   305 ---PYVCSTCGKTLASKQSLAQHLL---IHANVKPYSCSECGIHFRLKGSLIRHQGIHTG----- 358

  Fly   206 APLISP----------AASSVSSSTG-----------------SIRPVRDLIMSATGGAASTNIS 243
               :.|          :...|.|:.|                 :|:|.           |.:..|
Frog   359 ---VKPYHCTQFRKRFSRKEVCSTCGKQLKSKFSLNQHMKIHSNIKPF-----------ACSECS 409

  Fly   244 LTTVTNLSLNSVQATAVGMMPKMTGG---------------LITTAVGSNSGAIGGIG-GYNATS 292
            .:......|...|.|..|..|.....               ||.|  |....|....| |..:..
Frog   410 KSFRLKACLQLHQRTHTGEKPYTCNECRKSFAQVGQLKAHYLIHT--GEKPFACSECGKGLRSKE 472

  Fly   293 AEEISYKCRICEKVFGCSE---------TLQAHEKTHKSPR-YECADCGKGFSQLRNYKYHLSVH 347
            |......|...||.|.|||         :||.|::.|...: :||.:|||.|....|:|.|...|
Frog   473 ALRAHLLCHTGEKPFSCSECDKSFRVKSSLQIHQRVHTGEKPFECKECGKCFRIKTNFKSHQLTH 537

  Fly   348 RGTKEFAAECPECGKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPH- 411
            .|.|.|  ||.|||..|:.|..|..|..||...:.:||..|.|||:::...|.|..:|||.||:
Frog   538 TGIKRF--ECSECGMQFSHKNGLIKHQFIHTGERPFECVTCGKSFSRKFTLNKHQLVHTGEKPYV 600

  Fly   412 ---------------------------KCNECGKRFSRKMLLKQHMRTHSGEKPYQCSVCGKSFA 449
                                       .|.||||.|..:..||.||:||:|.|.:.|..|||||:
Frog   601 CTECGMGYKDKRSLVAHLRTHTGEAGIPCTECGKTFLSEKNLKFHMQTHTGVKRFACKECGKSFS 665

  Fly   450 DRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHTGCKPYVCPHPNCNQAFTQSSNMRT 514
            .:|....|..:|:|||||.|..|.|.|..|.:.|.|...|||.||:||  |.|...:|..::::.
Frog   666 KKSQFETHKLMHAGIKPFQCAECGKLFRHKSYFKIHQLIHTGEKPFVC--PECGLGYTTKTSLKN 728

  Fly   515 H-----------AKKC-----QYRPLD 525
            |           .|:|     |.|.|:
Frog   729 HLLCHTGEKPFACKECGKKYLQQRSLN 755

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	10/28 (36%)
		COG5048	<316..502	CDD:227381	82/214 (38%)
		C2H2 Zn finger	327..347	CDD:275368	8/19 (42%)
		zf-C2H2	356..377	CDD:278523	9/20 (45%)
		C2H2 Zn finger	357..377	CDD:275368	8/19 (42%)
		zf-H2C2_2	369..394	CDD:290200	10/24 (42%)
		C2H2 Zn finger	385..405	CDD:275368	7/19 (37%)
		zf-H2C2_2	397..422	CDD:290200	13/52 (25%)
		C2H2 Zn finger	413..433	CDD:275368	10/19 (53%)
		zf-H2C2_2	426..449	CDD:290200	13/22 (59%)
		zf-C2H2	439..461	CDD:278523	8/21 (38%)
		C2H2 Zn finger	441..461	CDD:275368	8/19 (42%)
		zf-C2H2	467..489	CDD:278523	8/21 (38%)
		C2H2 Zn finger	469..489	CDD:275368	7/19 (37%)
		C2H2 Zn finger	497..515	CDD:275368	4/17 (24%)
LOC100485704	XP_017950222.2	COG5048	<210..417	CDD:227381	44/239 (18%)
		C2H2 Zn finger	231..251	CDD:275368	3/19 (16%)
		C2H2 Zn finger	258..278	CDD:275368	3/19 (16%)
		C2H2 Zn finger	308..328	CDD:275368	3/22 (14%)
		C2H2 Zn finger	336..356	CDD:275368	5/19 (26%)
		C2H2 Zn finger	377..397	CDD:275368	2/19 (11%)
		COG5048	401..836	CDD:227381	115/372 (31%)
		C2H2 Zn finger	405..425	CDD:275368	3/19 (16%)
		C2H2 Zn finger	433..453	CDD:275368	1/19 (5%)
		C2H2 Zn finger	461..481	CDD:275368	3/19 (16%)
		C2H2 Zn finger	489..509	CDD:275368	6/19 (32%)
		C2H2 Zn finger	517..537	CDD:275368	8/19 (42%)
		C2H2 Zn finger	545..565	CDD:275368	8/19 (42%)
		C2H2 Zn finger	573..593	CDD:275368	7/19 (37%)
		C2H2 Zn finger	601..621	CDD:275368	0/19 (0%)
		C2H2 Zn finger	629..649	CDD:275368	10/19 (53%)
		C2H2 Zn finger	657..677	CDD:275368	8/19 (42%)
		C2H2 Zn finger	685..705	CDD:275368	7/19 (37%)
		C2H2 Zn finger	713..733	CDD:275368	5/21 (24%)
		C2H2 Zn finger	741..761	CDD:275368	5/15 (33%)
		C2H2 Zn finger	769..789	CDD:275368
		C2H2 Zn finger	797..817	CDD:275368
		C2H2 Zn finger	825..845	CDD:275368
		zf-H2C2_2	837..862	CDD:404364
		C2H2 Zn finger	853..873	CDD:275368
		zf-C2H2	878..900	CDD:395048
		C2H2 Zn finger	880..900	CDD:275368
		zf-H2C2_2	892..915	CDD:404364
		C2H2 Zn finger	908..928	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910