DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15269 and znf1046

DIOPT Version :9

Sequence 1:	NP_609739.2	Gene:	CG15269 / 34887	FlyBaseID:	FBgn0028878	Length:	587	Species:	Drosophila melanogaster
Sequence 2:	XP_017210830.1	Gene:	znf1046 / 100004513	ZFINID:	ZDB-GENE-030131-2092	Length:	418	Species:	Danio rerio

Alignment Length:	277	Identity:	100/277 - (36%)
Similarity:	145/277 - (52%)	Gaps:	23/277 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 SYKCRICEKVFGCSETLQAHEKTH-KSPRYECADCGKGFSQLRNYKYHLSVHRGTKEFAAECPEC 360
            ::.|:.|.|.|.....|..|.:.| :...:.|..|||.|.|::.:|.|:.:|.|.::|.  |.:|
Zfish    81 NFSCKQCRKSFSQKSKLDVHMRVHTREQPFTCEQCGKSFGQIQGFKAHMRIHTGERKFT--CRKC 143

  Fly   361 GKTFNDKGYLSSHLKIHRNRKEYECPYCPKSFNQRVAFNMHVRIHTGVKPHKCNECGKRFSRKML 425
            .|:|...|:.::|::||...|.:.|..|.|||.|:...:.|.|:|||.||:.|.:|||.||:|..
Zfish   144 EKSFYHAGHFAAHMRIHTGEKPFSCKQCGKSFCQKPNLDDHKRVHTGEKPYTCEQCGKSFSQKQN 208

  Fly   426 LKQHMRTHSGEKPYQCSVCGKSFADRSNMTLHHRLHSGIKPFSCPLCPKAFTKKHHLKTHLNYHT 490
            .|.|||.|:||:||.|..|||||....|:.:|.|.|:|.|||||..|.|:|:||.:|..|:..||
Zfish   209 FKTHMRIHTGERPYTCQKCGKSFRHAINLEVHMRTHTGEKPFSCKQCRKSFSKKPNLIAHMRVHT 273

  Fly   491 GCKPYVCPHPNCNQAFTQSS----NMRTHAKKCQYRPLDGLTVTS--------SALPVPGKQQTG 543
            ..||:.|  ..|.::|:|..    :||.|..:..|      |.|.        |.|....:..||
Zfish   274 REKPHTC--EQCGKSFSQKRDLYIHMRIHTGEKPY------TCTECGKGFSHISTLKHHMRTHTG 330

  Fly   544 PPPTLAMAMAQTFQMPP 560
            ..|.......::|...|
Zfish   331 EKPFACAQCGKSFTTKP 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15269	NP_609739.2	C2H2 Zn finger	300..320	CDD:275368	6/19 (32%)
		COG5048	<316..502	CDD:227381	79/186 (42%)
		C2H2 Zn finger	327..347	CDD:275368	8/19 (42%)
		zf-C2H2	356..377	CDD:278523	6/20 (30%)
		C2H2 Zn finger	357..377	CDD:275368	6/19 (32%)
		zf-H2C2_2	369..394	CDD:290200	9/24 (38%)
		C2H2 Zn finger	385..405	CDD:275368	8/19 (42%)
		zf-H2C2_2	397..422	CDD:290200	12/24 (50%)
		C2H2 Zn finger	413..433	CDD:275368	11/19 (58%)
		zf-H2C2_2	426..449	CDD:290200	14/22 (64%)
		zf-C2H2	439..461	CDD:278523	10/21 (48%)
		C2H2 Zn finger	441..461	CDD:275368	9/19 (47%)
		zf-C2H2	467..489	CDD:278523	10/21 (48%)
		C2H2 Zn finger	469..489	CDD:275368	8/19 (42%)
		C2H2 Zn finger	497..515	CDD:275368	6/21 (29%)
znf1046	XP_017210830.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910