Protein Alignment wwk and ano10b

DIOPT Version :10

• Sequence 1: NP_609738.1
• Gene: wwk / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_021326182.1
• Gene: ano10b / 565195
• ZFINID: ZDB-GENE-061013-169
• Length: 807
• Species: Danio rerio
• Alignment Length: 722
• Identity: 214/722 - (29%)
• Similarity: 347/722 - (48%)
• Gaps: 108/722 - (14%)

  Fly    85 RKVPYAGH----LMTPRRLWLNKIPTQCD--------VVIEFPEDAPDEALRWLLARIRSQPPAG 137
            :|.|..||    .:|....| :|:...|.        |:|:..|.......:|:::.|.:...||
Zfish   120 QKEPQEGHSTSTKVTGPSSW-SKVSCPCCTSTQIEPLVLIQLAESVQPITKQWIMSVIAAPVKAG 183

  Fly   138 LGLLVQVKAHESTRRNAFYVSAPVNVLFKAAEEARLPKRLRPDLGGALREFT--TRESHCFQQLR 200
             |..:.|...|..:.:...|:||...|.:..||..|.|..:   .|.::.|:  .|::.|
Zfish   184 -GAQLLVHPGEDMKGDMIVVAAPRCTLHRVTEELGLCKTYQ---DGDMKAFSFEDRDNFC----- 239

  Fly   201 GDVGSTALF-TSQERQWLVLQVLQGLRA----GCSDIEALHGRAAVAEGQSIVATWQESGLITQV 260
             ::..|..| |..|||::|...:..::|    ....|.|..|:....|  ||:...:::|||..:
Zfish   240 -NIDDTQQFLTLAERQFIVKHEMDLMKALEDQRIPGIPAPAGKLKARE--SILQKLEKAGLIRSI 301

  Fly   261 FPLHEPSSLTQLQTHWVKQ-IFAPQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGT-ILYC 323
            .|||:...|..|...|..| ....||||.|..|||..:|.||::|..||.:|..||:.|. |.:.
Zfish   302 TPLHDQERLADLGKQWYSQKSLWGQPLDYIHNYFGGTIAYYFSFLDFYTLSLFPPAILGIFITFF 366

  Fly   324 ILWGKGQTA-----------QDMGHVLFS------LFNVAWASLYLEAWKRYSVELAFRWGTLST 371
            :......||           .|..|:..|      :|::.|:::::|.|||.|..|::.|||.:.
Zfish   367 LPSANFSTAIETDSNASSKISDDDHLSVSSYMVQAVFSMLWSTIFMELWKRRSASLSYHWGTFNL 431

  Fly   372 PPELLEPPRPLYKGPLEENNVTGRLEPKEAPAWQRRAFRYLVSFPIIGCCLCVV---FAVMFLML 433
             .|..:.|||.:.|.:..|.|||||||. .|.|:|:....|||.|::|..|.:|   .|..::..
Zfish   432 -AEQFQEPRPGFHGEIGTNPVTGRLEPL-FPDWKRKMRMGLVSVPVVGFFLGLVILGMAGFYICE 494

  Fly   434 RFQDWWDSKLPEES---VLCCLSVIPKVLLAGAITLMDEAYFKLAVWLNDRENYRLQSKYENHLI 495
            |....|.    :||   ....|..:|.:.......::...|..:|:.|.:.||:|.:|.::.|..
Zfish   495 RLVSSWH----KESGSYFTAPLLYLPSIAHIVYTNVLGNVYRNVALKLTEAENHREESSFDYHHT 555

  Fly   496 AKVALFQFVNSFLSLFYIAFYLRDEEKLKEQLAGLLISRQIIGNLRESAIPYFLEQWKLAKLSFN 560
            .||.:|.|.|:|..||:|||:..|...|:::|:.|||..|::|...|..:|:.::::
Zfish   556 TKVLVFTFFNNFAVLFHIAFFKEDMPLLRKRLSSLLIVTQVVGQFTEVVVPFLVDRF-------- 612

  Fly   561 MWGALSPTQNVTRSLAEELATAEAELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKYDGTFS 625
                              |.:|...||.:         .||      :...:.:.||..:.|.|:
Zfish   613 ------------------LTSANRNLKED---------DPE------VDHLQAQGSLPAFPGLFA 644

  Fly   626 DHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQNALSI 690
            :::|:|||.||:.|||..:||.....|:|||.|||:||:||..:..:||...|||:|.||.|..:
Zfish   645 EYIELLVQFGYLSLFSCVYPLTAPLLLLNNLTEIRTDAYKLCKLFNKPFSAPVANLGVWQLAFEV 709

  Fly   691 LSLAAVIVNCALIGLSGQVSRLW---PGLTTAQTIILIVTLEHIMLGLRQALTWLLPELPSWLAA 752
            ||..:||.||.|:.||.:|.. |   .||:::|.|::.|.:||::|.::..|.:::|:.|.||..
Zfish   710 LSFISVISNCWLLLLSPRVKE-WTQEAGLSSSQVIVIAVIVEHVLLIVKMILAFIIPDEPDWLQV 773

  Fly   753 EIARAEH 759
            :..:.|:
Zfish   774 KREQIEY 780

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wwk	NP_609738.1	Anoctamin	289..756	CDD:461349	155/493 (31%)
ano10b	XP_021326182.1	Anoctamin	331..777	CDD:461349	155/493 (31%)