Protein Alignment wwk and ano7

DIOPT Version :10

• Sequence 1: NP_609738.1
• Gene: wwk / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_009289708.1
• Gene: ano7 / 556876
• ZFINID: ZDB-GENE-130530-576
• Length: 883
• Species: Danio rerio
• Alignment Length: 886
• Identity: 211/886 - (23%)
• Similarity: 332/886 - (37%)
• Gaps: 275/886 - (31%)

  Fly   120 DEALRWLLARIRSQPPAGLGLLVQVKAHESTRRNAFYVSAPVNVLFKAAEEARL----------- 173
            |...:|....:.....|||...::......|:.....:|||.|||...|||..|
Zfish    77 DTHRKWRTEFLSKLQEAGLHQEMKEVVQGKTKTTYVLLSAPWNVLCYYAEEISLRVPLQVVTTPI 141

  Fly   174 -------------PKRLRPDLGGALREF------TTRESHCFQQLRGDVGSTALFTSQERQWLVL 219
                         |..:..|:.....::      ||:    .::..|.......|.:.:|..::.
Zfish   142 SNWSETILEKLHIPNIMAQDVPNYPPDYYTCPFRTTK----LERFLGHENKDTFFKTTQRHQILY 202

  Fly   220 QVLQGLRAGCSDIEALHGRAAVAEGQSIVATWQESGLITQVFPLHE-----------PSSLT--Q 271
            ::|.....|           |:..|:..:.......::|..|||||           |..|.  |
Zfish   203 EILARTPYG-----------ALKRGEVGIGRLVSEKVLTAAFPLHEGPFQLPKTQEDPQCLNMRQ 256

  Fly   272 LQTH-------WVKQIFAPQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILY------- 322
            :..|       |.|.    ||||.|..|||.|:||||||||.||..|...||.|.|::
Zfish   257 ILHHYWARWACWRKY----QPLDHIREYFGEKIALYFAWLGFYTGWLLPAAVVGFIIFLFGIWLM 317

  Fly   323 ---------------------------------CILWGKGQTAQDMGHVLFSLFNVAWASLYLEA 354
                                             |..:..|....:.|.|.||:|...||..:||.
Zfish   318 VTDVPAEELCSSGNAFIMCPLCNICSHWNLSSICYTYKAGLLFDNGGTVFFSIFMSLWAVTFLEY 382

  Fly   355 WKRYSVELAFRWGTLSTPPELLEPPRPLYK--GPLE-ENNVTGRLEPKEAPAWQRRAFRYLVSFP 416
            |||.|..|:.|| ..|...|:.|.|||.:.  .|:. .|.|||..||....|  ||..|.|....
Zfish   383 WKRTSSILSHRW-DCSEFEEIEERPRPEFTALAPMTVRNPVTGAEEPYFPEA--RRLSRTLTGNM 444

  Fly   417 IIGCCLCVVFAVMFLMLRFQDWWDSKLPEESVLCCLSVIPKVL-----------------LAGA- 463
            :|  .|.:...::|||              :::...:::..::                 |.|:
Zfish   445 VI--ILMISIVLIFLM--------------AIILYRTILSIIIYRSQSAFFIFSAGRIASLTGSM 493

  Fly   464 -----ITLMDEAYFKLAVWLNDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAFY------- 516
                 |.|:...|..||..|...|.:|.|::|||..|.||.:|||||.:.|..||||:
Zfish   494 LNLLVILLLSRLYTYLAQCLTRWEMHRTQTEYENAFILKVFIFQFVNFYSSPVYIAFFKGRFVGY 558

  Fly   517 ---------LRDEE--------KLKEQLAGLLISRQIIGNLRESAIPYFLEQWKLAKLSFNMWGA 564
                     :|:|:        :|.::|..:::.:|:|.|::|..:|.....|...||.
Zfish   559 PGSYNTLLGIRNEDCGASGCLIELAQELLVIMVGKQVISNIQEFVLPKLKTWWHKRKLK------ 617

  Fly   565 LSPTQNVTRSLAEELATAEAELKAESTGTPTKSQ----QPESSSKRNIGQAEIESSLYKYDGTFS 625
                                         |.:||    :|:::|:  |...|.:..|...:|.|.
Zfish   618 -----------------------------PARSQEVIDEPDTNSQ--INPWENDYQLLVCEGLFD 651

  Fly   626 DHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQNALSI 690
            ::|||::|.|::.:|.||.|||.:.|||||.:|:|.||.|....::||..:|..:||.|...|..
Zfish   652 EYLEMVLQFGFITIFVAACPLAPLFALINNWVEVRLDAQKFVCEYRRPVVERAQDIGIWLTILQF 716

  Fly   691 LSLAAVIVNCALI-----------------GLSG----------------QVSRLWPGL------ 716
            :|..|||.|..||                 .:||                ::|..:.||
Zfish   717 ISYLAVISNAFLIAFTSDFLPRLFYRYTAGSMSGYINFTLSVAPANFTQNEMSCRYRGLRDEKGQ 781

  Fly   717 -------TTAQTIILIVTLEHIMLGLRQALTWLLPELPSWLAAEIARAEHCRREMQCKGTSPRPT 774
                   ..|..:..::..||::|.:.:.:.|::|::|..:..:|.|..:..:|...:.
Zfish   782 NTQDYYHLLAIRLSFVIIFEHVVLLIGRIIDWIVPDIPEEVEIKIKREHYMAKEALAEN------ 840

  Fly   775 PPTPQSTTSTQPEQEGPGGLQMESGANTTRDQSMESQVAED 815
                ||.:.:..|:.|....::.....|....:..|..:||
Zfish   841 ----QSLSKSVLEEMGRQNFELRQRIRTQSPTNNMSPTSED 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wwk	NP_609738.1	Anoctamin	289..756	CDD:461349	158/606 (26%)
ano7	XP_009289708.1	Anoct_dimer	42..274	CDD:465044	40/215 (19%)
		Anoctamin	277..829	CDD:461349	158/607 (26%)