Protein Alignment CG15270 and ano1a

DIOPT Version :9

• Sequence 1: NP_609738.1
• Gene: CG15270 / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_009301746.1
• Gene: ano1a / 407698
• ZFINID: ZDB-GENE-121127-3
• Length: 966
• Species: Danio rerio
• Alignment Length: 943
• Identity: 196/943 - (20%)
• Similarity: 333/943 - (35%)
• Gaps: 335/943 - (35%)

  Fly    50 DFTDDN------NFESNLRRRKGKIISCAKETIENASRQLRRKVPYAGHLMTPRRLWLNKIPTQC 108
            |:.||:      .||.|||           |......::...|:|..|.|         ||
Zfish   151 DYHDDDQRLRREEFEENLR-----------EMGLEMEKEEGNKIPGVGFL---------KI---- 191

  Fly   109 DVVIEFPEDAPDEALRWLLARIRSQPPAGLGLLVQVKAHESTRRNAFYVSAPVNVLFKAAE-EAR 172
                    .||.|.|......::.:.|.       :|.:|.:..|        :::.||:. ..:
Zfish   192 --------HAPWEVLCREAEFMKLKMPT-------IKKYEVSHGN--------SIVEKASRFMQK 233

  Fly   173 LPKRLRPDLGGALRE--------FTTRESHCFQQLRGDVGS-TALFTSQERQWLVLQVLQGLRAG 228
            ....|:|.:|....|        |:..:.|.|     |:.. .:.|.|:.|..:|.::|:  |..
Zfish   234 FTAPLQPKVGDRQIEHEKHLSYPFSREKQHLF-----DLSDRNSFFDSKTRSSIVYEILK--RTK 291

  Fly   229 CSDIEALHGRAAVAEGQSIVATWQESGLITQVFPLH---------EPSSLTQLQTHWVKQ--IFA 282
            |:..:.:.|          :.:...:|:.|..:|||         |.:....|...|...  .:.
Zfish   292 CTRAKYIMG----------IISLLGNGIYTSAYPLHDGDIDDVHAEINDRKILYEEWASYSIFYK 346

  Fly   283 PQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILY------------------------- 322
            .||:..|..|||.||.|||||||.||..|...|:.|.|::
Zfish   347 YQPIGLIRKYFGEKVGLYFAWLGVYTQMLIPAAIVGVIVFLYGCATVDDNIPSMEICDERNNITM 411

  Fly   323 -------CILW------GKGQTA---QDMGHVLFSLFNVAWASLYLEAWKRYSVELAFRW---GT 368
                   |..|      |..:.:   .:...|.|::|...||::::|.|||..|.|.:.|   |.
Zfish   412 CPMCDRACSYWKLVTACGTARASHLFDNAATVFFAIFMALWAAMFMEHWKRRQVRLNYLWDLTGF 476

  Fly   369 LSTPPELLEPPRPLYKGPLEENNVTGRLEPK----------EAPAWQRRAFRYLVSFPIIGCCLC 423
            ..|..:....||..|:..:.:.::.....||          ..||       |:.....:...:|
Zfish   477 EDTEGKQKSHPRAEYEFHVMKKSLRKEKSPKAGNVKLTCTDRMPA-------YMTIIITMIFLIC 534

  Fly   424 VVFAVMFLMLRFQDWWDSKLPEESVLCCL----------SVIPKVLLAGA------ITLMDEAYF 472
            |..|::|.::.::         .|::..|          ::...|...||      |.:|||.|.
Zfish   535 VTLAIVFGVVLYR---------VSIMTALHMSSTPTFRSNIRATVKTTGAIINLIIIIIMDEVYG 590

  Fly   473 KLAVWLNDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAF-------------YLRDEEKLK 524
            .:|.||...|..:....:|..||.|..:.:|.|:|..:.|:||             |:....:::
Zfish   591 AVARWLTIMEVPKTDKSFEERLIFKTFVLKFANAFTPIVYLAFFRGRLIGRPGKYIYVMGSYRME 655

  Fly   525 E------------QLAGLLISRQII-GNLRESAIPYFLEQWKLAKLSFNMWGALSPTQNVTRSLA 576
            |            ||...::.:|:| .||.|..:|      |:.||
Zfish   656 ECAHAGCLMELCIQLCITMLGKQLIQNNLFEIGVP------KIKKL------------------- 695

  Fly   577 EELATAEAELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKYD---------GTFSDHLEMLV 632
                                .:|.:...|.   |.|:..:|::::         |...:::||::
Zfish   696 --------------------LRQRKIDPKH---QEELNKTLHRHEKDHFLGPFVGLNPEYMEMII 737

  Fly   633 QMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVI 697
            |.|.|.||.|:||||.:.||:||::|||.||.|.....:||...|..:||.|...|..||..|||
Zfish   738 QFGMVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPIAVRAKDIGIWYTLLRGLSKVAVI 802

  Fly   698 VNCALIGLSG-----------------------------QVSRLWPGLTTAQTIIL--------- 724
            ||..:|..:.                             .|:...||....:.:.|
Zfish   803 VNAFVISFTSDFIPRLVYQYMYSPDGTLHGFVNHTLSYFNVTHFQPGTEPLEPMHLGYQVDTCRY 867

  Fly   725 -----------------------------IVTLEHIMLGLRQALTWLLPELPSWLAAEIARAEH- 759
                                         ::..:::::.:...:.||:|::|..::.:|.:..:
Zfish   868 KDYRDPPWSDTPYEFSREFWAILAARFAFVILFQNVVMLMSDFVDWLIPDIPKDISLKIHKERNL 932

  Fly   760 -----CRREM--QCKGTSPRPTPPTPQSTTSTQ 785
                 .:||.  :.:.|...|:|...:|..|:|
Zfish   933 IIELFMKREQGKKYRNTMNDPSPQPLRSRPSSQ 965

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	137/640 (21%)
ano1a	XP_009301746.1	Anoct_dimer	91..350	CDD:292796	50/262 (19%)
		Anoctamin	353..930	CDD:282414	137/640 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920