Protein Alignment CG15270 and Ano7

DIOPT Version :9

• Sequence 1: NP_609738.1
• Gene: CG15270 / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: NP_001004071.1
• Gene: Ano7 / 367318
• RGDID: 1302987
• Length: 860
• Species: Rattus norvegicus
• Alignment Length: 956
• Identity: 223/956 - (23%)
• Similarity: 344/956 - (35%)
• Gaps: 305/956 - (31%)

  Fly     6 EVRDGVPFSEQQQSSEDVPDSTATTTATSTAG---------ELGGGPRDGGEDDFTDDN-----N 56
            |..:|..:....|:||......|.:...|:|.         |.....|:....|.||.:     .
  Rat    21 EAGNGCSYGSTAQASEAGKQQVAPSRVGSSANPPIDFVLVWEEDLRSRENPTQDKTDTHEIWRET 85

  Fly    57 FESNLRRRKGKIISCAKETIENASRQLRRKVPYAGHLMTPRRLWLNKIPTQCDVVIEFPEDAPDE 121
            |..|||....||.....:....|...:....|:|........|.| |:|.|         :.|::
  Rat    86 FLENLRVAGLKIDQRDVQDEAAAVHYILLSAPWAVLCYYAEDLRL-KLPLQ---------ELPNQ 140

  Fly   122 ALRW-------------LLARIRSQPPAGLGLLVQVKAHESTRRNAFYVSAPVNVLFKAAEEARL 173
            |..|             ||..:...||.                   |.|..    |||::
  Rat   141 ASNWSATLLEWLGIPNILLENVPDTPPE-------------------YYSCQ----FKASK---- 178

  Fly   174 PKRLRPDLGGALREFTTRESHCFQQLRGDVGSTALFTSQERQWLVLQVLQGLRAGCSDIEALHGR 238
                                  .|...|.......|||.:|..::.::|.....|       |.:
  Rat   179 ----------------------LQWFLGSDNQDTFFTSTKRHQILFEILAKTPYG-------HQK 214

  Fly   239 AAVAEGQSIVATWQESGLITQVFPLHE------PSS-----LTQLQT---HWVK--QIFAPQPLD 287
            ..:.....::|    .|:.:..||||:      |.|     |||.|.   ||.:  :....||||
  Rat   215 KGLFGIDQLLA----EGVFSAAFPLHDGPFSVVPESSQVLGLTQRQVLFKHWARWGKWRKYQPLD 275

  Fly   288 DIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILY------------------------------ 322
            .:..|||.||||||||||.||..|...||.||:::
  Rat   276 HVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLAGCFLVFSDVPTQELCHSSDTFDMCPLCS 340

  Fly   323 ----------CILWGKGQTAQDMGHVLFSLFNVAWASLYLEAWKRYSVELAFRWGTLSTPPELLE 377
                      |.|...|:.....|.|.||||...||.|.||.|||.:..||:|| ..|...::.|
  Rat   341 DCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRW-DCSDYEDIEE 404

  Fly   378 PPRPLY--KGPLEE-NNVTGRLEPKEAPAWQRRAFRYLVS--------FPIIGCCLCVVF--AVM 429
            .|||.:  ..|:.. |.:||..||....  :.|..|.|..        ..:|.|.:.::.  |||
  Rat   405 RPRPQFAATAPMTALNPITGEDEPYFPE--KNRVRRMLAGSVVLLMMVAVVIMCLVSIILYRAVM 467

  Fly   430 FLML-----RFQDWWDSKLPEESVLCCLSVIPKVLLAGAITLMDEAYFKLAVWLNDRENYRLQSK 489
            .:::     .|...|.|::        .|:...|:....|.::.:.|..||..|...|.:|.|:.
  Rat   468 AIIVSKSNNAFLSAWASRI--------ASLTGSVVNLVFILILSKVYVILAQVLTRWEMHRTQTA 524

  Fly   490 YENHLIAKVALFQFVNSFLSLFYIAFY----------------LRDEE--------KLKEQLAGL 530
            :|:....||.:|||||.:.|..||||:                :|:||        :|.::|..:
  Rat   525 FEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGVRNEECPAGGCLSELAQELLVI 589

  Fly   531 LISRQIIGNLRESAIPYFLEQWKLAKLSFNMWGALSPTQNVTRSLAEELATAEAELKAESTGTPT 595
            ::.:|||.|::|..:|.....|:  ||.
  Rat   590 MVGKQIINNVQEVLVPKLKGCWQ--KLC------------------------------------- 615

  Fly   596 KSQQPESSSKRNIGQAEIESSLYKYDGTFSDHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIR 660
             |::.::....|....|.:..|...:|.|.::|||::|.|:|.:|.||.|||.:.||:||.:|||
  Rat   616 -SRRKKAGMGANPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIR 679

  Fly   661 SDAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVIVNCALIGLSGQ----------------- 708
            .||.|....::||..:|..:||.|.:.|:.|:..|||.|..|:..|..
  Rat   680 LDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRVYYSWTRAPDLRG 744

  Fly   709 -----VSRLWPGLTTAQT--------------------------IILIVTLEHIMLGLRQALTWL 742
                 ::|..|..|:|..                          :..::..||::....:.|..|
  Rat   745 FLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSTGRFLDLL 809

  Fly   743 LPELPSWLAAEIARAEHCRREMQC-----------KGTSPRPTPPT 777
            :|::|..:..::.|..:..::...           ||..|..:.|:
  Rat   810 VPDIPESVEIKVKREYYLAKQALADNEALLGATGVKGEQPPSSEPS 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	153/598 (26%)
Ano7	NP_001004071.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..50		5/25 (20%)
		Anoct_dimer	54..274	CDD:292796	55/289 (19%)
		Anoctamin	277..824	CDD:282414	152/597 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920