Protein Alignment wwk and Axs

DIOPT Version :10

• Sequence 1: NP_609738.1
• Gene: wwk / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: NP_476777.1
• Gene: Axs / 32645
• FlyBaseID: FBgn0000152
• Length: 646
• Species: Drosophila melanogaster
• Alignment Length: 621
• Identity: 181/621 - (29%)
• Similarity: 294/621 - (47%)
• Gaps: 112/621 - (18%)

  Fly   156 YVSAPVNVLFKAAEEARLPKRLRPDLGGALREFTTRESHCFQQLRGDVGSTALFTSQERQWLVLQ 220
            |:||.|:.|.:.|:.|.|.|            .||  :|..|:......|..|.....::    |
  Fly    99 YLSASVDTLLRLADAAELEK------------MTT--THSMQKFNHGCISDFLLPGMGKE----Q 145

  Fly   221 VLQGLRAGCSDIEALHGRAAVAEGQSIVATWQESGLITQVFPLHEPSSLTQLQTHW-VKQIFAPQ 284
            :|:     ..:|..|. :..:.:|   :.::.:.|.|..:||||:...|.:.  :| :|:  ...
  Fly   146 ILR-----YCEIPVLI-KDVIQDG---IKSYVQKGYIEDMFPLHDILYLERF--NWNLKR--TKL 197

  Fly   285 PLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILYCILWGKGQTAQDMGHVLFSLFNVAWAS 349
            |::||..|||..:.|||.::..||.||..|::||.:.|..         |:...|...|.|.|.:
  Fly   198 PIEDIRNYFGSSIGLYFGFIEFYTKALIFPSLFGILQYVF---------DLNISLVCSFYVVWTT 253

  Fly   350 LYLEAWKRYSVELAFRWGTLSTPPELLEPPRPLYKGPLEENNVTGRLE---PKEAPAWQRRAFRY 411
            ::||.|||.....::||||:..  ..|:.||..|.|.|:.:.:||::.   |......|    .|
  Fly   254 IFLELWKRKCAGYSYRWGTIEM--SSLDKPRSAYTGQLKPDPITGKMTLHYPMRYTYLQ----MY 312

  Fly   412 LVSFPII-GCCLCVVFAVMFLMLRFQ-----------DWWDSKLPEESVLCCLSVIPKVLLAGAI 464
            .:|:|:: |   |||.|..|.:.:||           |.|            |..:|.::.:..|
  Fly   313 CISYPVVLG---CVVAAGWFALYQFQIEAEVLADFGPDSW------------LLYVPVIVQSVLI 362

  Fly   465 TLMDEAYFKLAVWLNDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAFYLRDEEKLKEQLAG 529
            .:...||.|||.:|.:.||:|.:|:|:.|.:.|:.||:.||:|.|.|||||.|.|..:||.||..
  Fly   363 AIFSWAYEKLATFLTNLENHRTRSQYDRHRVNKLMLFEIVNNFFSQFYIAFVLHDLRQLKYQLMM 427

  Fly   530 LLISRQIIGNLRESAIPYF--LEQWKLAKLSFNMWGALSPTQNVTRSLAEELATAEAELKAESTG 592
            .|:..|::...:|..||..  |.| |.|:...             |.:|||...:.::|.
  Fly   428 QLLVFQLLCIAQEIGIPLLAVLRQ-KYAEFRH-------------REVAEEKLRSISDLP----- 473

  Fly   593 TPTKSQQPESSSKRNIGQAEIESSLYKYDGTFSDHLEMLVQMGYVVLFSAAFPLAGVCALINNLM 657
                          ...|:..||.|.:|..|:.|:|::.:|.|:||||:|..|.|.:.||:||:.
  Fly   474 --------------RYEQSFYESGLDEYHSTYEDYLQVCIQFGFVVLFAAVAPFAAIGALLNNVF 524

  Fly   658 EIRSDAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVIVNCALIGLSGQVSRLWPGLTTAQTI 722
            .:..|.:||.::.:|||.:|..|||.||.|..:||:.:::.||.|:.|...|...:.....:...
  Fly   525 AVHIDMWKLCNIFKRPFARRAKNIGAWQLAFELLSVMSLLSNCGLLFLQPNVKDFFSHWLPSVPD 589

  Fly   723 ILIVTLEHIMLGLRQALTWLLPELPSWLAAEIARAE 758
            :..|..||::|||:..:..::.|.|.|:...:.:|:
  Fly   590 LSFVIFEHLLLGLKFLIHKVIHERPRWVRIGLLKAD 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wwk	NP_609738.1	Anoctamin	289..756	CDD:461349	149/483 (31%)
Axs	NP_476777.1	Anoctamin	202..623	CDD:461349	149/483 (31%)