Protein Alignment CG15270 and Ano3

DIOPT Version :9

• Sequence 1: NP_609738.1
• Gene: CG15270 / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_038962388.1
• Gene: Ano3 / 311287
• RGDID: 1308873
• Length: 981
• Species: Rattus norvegicus
• Alignment Length: 905
• Identity: 207/905 - (22%)
• Similarity: 318/905 - (35%)
• Gaps: 324/905 - (35%)

  Fly    55 NNFESNLRRRKGKIISCAKETIENASRQLRRKVPYAGHLMTPRRLWLNKIPTQCDVVIEFPEDAP 119
            |.||.|||                |...:..|.|...:   |..::: |:....|.:.::.|
  Rat   181 NTFEKNLR----------------AEGLMLEKEPAVAN---PDIMFI-KVHIPWDTLCKYAE--- 222

  Fly   120 DEALRWLLARIRSQPPAGLGLLVQVKAHESTRRNAFYVS------APVNVLFKAAEE------AR 172
                     |:..:.|              .|:..:|..      :.|...||..::      ..
  Rat   223 ---------RLNIRVP--------------FRKKCYYTDQKNKSMSRVQKYFKRIKKWMSQNPMV 264

  Fly   173 LPKRLRPDLGGALREFTTRESHCFQQ--LRGDV------GSTALFTSQERQWLVLQVLQGLR--A 227
            |.|...|:|         .||.|:..  .|..:      .....|::..|..:|..:|:..:  .
  Rat   265 LDKSAFPEL---------EESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYEN 320

  Fly   228 GCSDIEALHGRAAVAEGQSIVATWQESGLITQVFPLHE---PSSLTQLQTH-------------- 275
            |.|.:..   |..:..|..|.|           ||.||   .||| .::||
  Rat   321 GISKVGI---RKLINNGSYIAA-----------FPPHEGAYKSSL-PIKTHGPQNNRHLLYERWA 370

  Fly   276 ----WVKQIFAPQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILY---CILWGKGQTAQ 333
                |.|.    ||||.|..|||.|:.|||||||.||..|...||.|..::   .:...:.|.:|
  Rat   371 RWGMWYKH----QPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAVVGLCVFFYGLVTMNESQVSQ 431

  Fly   334 DM-------------------------------------GHVLFSLFNVAWASLYLEAWKRYSVE 361
            ::                                     |.|.|::|...||:::||.|||....
  Rat   432 EICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSI 496

  Fly   362 LAFRWGTLSTPPELLEPPRPLYKGPLEE----NNVTGRLEPKEAPAWQRRAFRYLVS----FPII 418
            |.:.|..:....| .|..||.::.....    |.:||:.||.:..:  .:..|.|||    |.:|
  Rat   497 LTYTWDLIEWEEE-EETLRPQFEAKYYRMEIINPITGKPEPHQPSS--DKVTRLLVSVSGIFFMI 558

  Fly   419 GCCLCVVFAV----MFLMLRF---------QDWWDSKLPEESVLCCLSVIPKVLLAGAITLMDEA 470
            ...:..||||    :.:|.:|         |.|   :........|::.|       .|.|::.|
  Rat   559 SLVITAVFAVVVYRLVVMEQFASFKWNFIKQHW---QFATSGAAVCINFI-------IIMLLNLA 613

  Fly   471 YFKLAVWLNDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAFYLR-------------DEEK 522
            |.|:|..|.:.|..|.:|::||....|:.||||||...|:|||||:|.             :..:
  Rat   614 YEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFERWR 678

  Fly   523 LKE------------QLAGLLISRQIIGNLRESAIPYFLEQWKLAKLSFNMWGALSPTQNVTRSL 575
            |:|            |:..::..:||..|..|...|.....|...|:...:..|..|......:|
  Rat   679 LEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDASIPQWENDWNL 743

  Fly   576 AEELATAEAELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKYDGTFSDHLEMLVQMGYVVLF 640
                                   ||     .||            .|...::|||::|.|:..:|
  Rat   744 -----------------------QP-----MNI------------HGLMDEYLEMVLQFGFTTIF 768

  Fly   641 SAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVIVNCALIG- 704
            .||||||.:.||:||::|||.||:|.....:||...|..:||.|...|..:.:.|||.|..:|.
  Rat   769 VAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAI 833

  Fly   705 ---------------------------LSGQVS-------------------------------- 710
                                       |.|.|:
  Rat   834 TSDYIPRFVYEYKYGPCANHVKQNENCLKGYVNNSLSFFDLSELGIGKSGYCRYRDYRGPPWSSK 898

  Fly   711 ------RLWPGLTTAQTIILIVTLEHIMLGLRQALTWLLPELPSWLAAEIARAEHCRREM 764
                  :.|..|  |..:..|:..||::.|::..:.:|:|::|..|...|.|.::..:||
  Rat   899 PYEFTLQYWHIL--AARLAFIIVFEHLVFGIKSFIAYLIPDIPKGLRERIRREKYLVQEM 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	152/620 (25%)
Ano3	XP_038962388.1	Anoct_dimer	157..381	CDD:406563	50/273 (18%)
		Anoctamin	384..949	CDD:398306	151/619 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920