Protein Alignment CG15270 and Ano1

DIOPT Version :9

• Sequence 1: NP_609738.1
• Gene: CG15270 / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_017444724.1
• Gene: Ano1 / 309135
• RGDID: 1310786
• Length: 1066
• Species: Rattus norvegicus
• Alignment Length: 1022
• Identity: 214/1022 - (20%)
• Similarity: 344/1022 - (33%)
• Gaps: 389/1022 - (38%)

  Fly    41 GGPRDGGE-----DDFTDDNNFESNLRRRKGKIISCAKETIENASRQLRRKVPYAGHLMTPRRLW 100
            |.|.|.|.     |...||..|                           |:..|.|:|:
  Rat   163 GSPVDVGSPEAPMDYHEDDKRF---------------------------RREEYEGNLL------ 194

  Fly   101 LNKIPTQCDVVIEFPEDAPDEALRWLLARIRSQPPAGLGLLVQVKAHESTRRNAFYVSAPVNVLF 165
                  :..:.:|..||          .:|.     |:|.   ||.|           ||.:||.
  Rat   195 ------EAGLELERDED----------TKIH-----GVGF---VKIH-----------APWHVLC 224

  Fly   166 KAAE--EARLPKR-------------------------LRPDLGGALREFTTRESHCF----QQL 199
            :.||  :.::|.:                         ::|.:.....:.|.|.|:.|    |.|
  Rat   225 REAEFLKLKMPTKKVYHISETRGLLKTINSVLQKITDPIQPKVAEHRPQTTKRLSYPFSREKQHL 289

  Fly   200 RGDVGSTALFTSQERQWLVLQVLQGLRAGCSDIEALHGRAAVAEGQ------------------- 245
            .......:.|.|:.|..:|.::|:  |..|:..:...|:   .||:
  Rat   290 FDLTDRDSFFDSKTRSTIVYEILK--RTTCTKAKYSMGQ---GEGRRKDSALLSKRRKCGKYGIT 349

  Fly   246 SIVATWQESGLITQVFPLH---------EPSSLTQLQTHWVKQ--IFAPQPLDDIAAYFGVKVAL 299
            |::|    :|:.:..:|||         |.:....|...|...  .:..||:|.:..|||.||.|
  Rat   350 SLLA----NGVYSAAYPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGL 410

  Fly   300 YFAWLGHYTCALGVPAVFGTILY--------------------------------CILWGKGQ-- 330
            ||||||.||..|...::.|.|::                                |..|....
  Rat   411 YFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSAC 475

  Fly   331 -TAQ------DMGHVLFSLFNVAWASLYLEAWKRYSVELAFRWGTLSTPPE---LLEPPRPLYKG 385
             ||:      :...|.||:|...||:.::|.|||..:.|.:||.......|   :.:.||..|:.
  Rat   476 ATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEA 540

  Fly   386 PL-------EENNVTGRLEPKEAP-----------------------AWQRRAFRYLVSFPIIGC 420
            .:       |..|...|....|.|                       .|:.|...|..:...|..
  Rat   541 RVLEKSLRKESRNKEKRRNVPEEPTNKWKQRVRTAMAGVKLTDKVKLTWRDRFPAYFTNLVSIIF 605

  Fly   421 CLCVVFAVMFLMLRFQDWWDSKLPEESVLCCLSVIPKVLLAGA-------ITLMDEAYFKLAVWL 478
            .:.|.||::..::.::....:.|...|.....|.|...:.|.|       |.|:||.|..:|.||
  Rat   606 MIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWL 670

  Fly   479 NDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAFY-----------------LRDEE----- 521
            ...|..:.:..:|..|..|..|.:||||:..:||:||:                 .|.||
  Rat   671 TKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGG 735

  Fly   522 ---KLKEQLAGLLISRQII-GNLRESAIP---YFLEQWKLAKLSFNMWGALSPTQNVTRSLAEEL 579
               :|..||:.:::.:|:| .||.|..||   .|:...||.:.|
  Rat   736 CLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQS--------------------- 779

  Fly   580 ATAEAELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKYDGTFSDHLEMLVQMGYVVLFSAAF 644
                            .|.:.|...::.  :.|::.:|..:.|...:::||::|.|:|.||.|:|
  Rat   780 ----------------PSDREEYIKRKQ--RYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASF 826

  Fly   645 PLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVIVNCALI------ 703
            |||.:.||:||::|||.||.|.....:||...|..:||.|.|.|..:...|||:|..:|
  Rat   827 PLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDF 891

  Fly   704 --------------------------------------------GLSGQVSR------------- 711
                                                        |...|:.|
  Rat   892 IPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHK 956

  Fly   712 ------LWPGLTTAQTIILIVTLEHIMLGLRQALTWLLPELPSWLAAEI-----------ARAEH 759
                  .|..|  |..:..::..:::::.:...:.|::|::|..::.:|           .|.|.
  Rat   957 YDISKDFWAVL--AARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQ 1019

  Fly   760 CR-------------REMQCKGTSPRPTPPTPQSTTSTQPEQEGPGG 793
            .:             |::.|...||...|....|  |..|..|..||
  Rat  1020 GKQQLLDTWMEKEKPRDVPCNNHSPTAHPEAGDS--SPVPSYEYHGG 1064

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	145/658 (22%)
Ano1	XP_017444724.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920