Protein Alignment wwk and LOC1272176

DIOPT Version :10

• Sequence 1: NP_609738.1
• Gene: wwk / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_061511232.1
• Gene: LOC1272176 / 1272176
• VectorBaseID: AGAMI1_003147
• Length: 1143
• Species: Anopheles gambiae
• Alignment Length: 1105
• Identity: 260/1105 - (23%)
• Similarity: 392/1105 - (35%)
• Gaps: 363/1105 - (32%)

  Fly     2 HGNEEVRDGVPFSEQQQSSEDVPDSTATTTATSTAGELGGGPRDGGEDDFTD--DNNFESNL--- 61
            |..|:||.|         |.| ..|.|..|.....|:.|.|.|...|....|  .|...:||
Mosquito   133 HSAEDVRFG---------SVD-SGSGAGPTTDRRLGDDGAGLRQTTEALLHDSRSNGGLANLPYV 187

  Fly    62 -------RRRKGKIISCAKETIENASRQLRRKVPYAG-----------------HLMTPR----- 97
                   ...||.|....|.||  .|.:...|||.|.                 |..|.:
Mosquito   188 PRPGATSNGAKGFISGILKPTI--LSTEYNEKVPSASTSYSSLPYRNDYRPGSEHDRTKQIVTYT 250

  Fly    98 ----RLW-----LNKIPTQCDVVIEF-PEDAPDEALRWLLARIRSQPPAGLGLLVQVKAHESTRR 152
                |.|     ..:|   .|.|:.| .||...||.:......|:....||    |::.....|.
Mosquito   251 QWKSRTWKYFQDQRRI---VDYVLAFNGEDENAEAKQRRAIYQRNLESEGL----QIETENCQRI 308

  Fly   153 NAFYVSAPVNVLFKAAE--EARLP-KRLRPDLGGALREFTTR----------------------- 191
            :...:..|.|||....|  :.::| |:|.......:|:|:.:
Mosquito   309 HFVKIHVPENVLSHYCEIMKMQMPMKKLENQDKIIMRDFSIQSTLVRLFRRPLFNFVIIDRQKFA 373

  Fly   192 --ESHCFQQLRGDVGSTALFTSQERQWLVLQVLQGLRAGCSD--IEALHGRAAVAEGQSI-VATW 251
              |.....:...|  ...||..:|:.:..    ..:|...:.  :|..:...||.|.:.| :...
Mosquito   374 PPEYRLMYEYSRD--KPYLFDDREQNFFT----PSIRIAVAHFILERTYFSEAVEEKKDIGIRRL 432

  Fly   252 QESGLITQVFPLHEPSSLTQLQ---------------THWVKQIFAPQPLDDIAAYFGVKVALYF 301
            .|..:....:|||:  ..|.|:               :.|:|.    ||||.|..|||||:|:||
Mosquito   433 MEDQVYLDAYPLHD--GCTDLRSSCQRALLLEEWASISKWIKH----QPLDHIKEYFGVKIAMYF 491

  Fly   302 AWLGHYTCALGVPAVF--------------------------GTIL------YCILWGKGQTA-- 332
            ||||.||..| :||..                          |||:      ||..|....|.
Mosquito   492 AWLGFYTHML-IPASVVGLICFFYGLLTYPANRISQEICDDNGTIMCPQCDKYCDYWYLRTTCNI 555

  Fly   333 QDMGH-------VLFSLFNVAWASLYLEAWKRYSVELAFRWGTLSTPPELLEPPRPLYKGPLEE- 389
            ..:.|       ::||:|...||:||||.|||||..:..||| ::....|.|||||.|...|:.
Mosquito   556 SKLAHIFDNEMTIVFSIFMSVWATLYLEMWKRYSSRIQHRWG-ITEYCSLAEPPRPQYLSRLKNI 619

  Fly   390 -----NNVTGRLEPKEAPAWQRRAFRYLVSFPIIGCCLCVVFAVMF--------LMLRFQDWWDS 441
                 |..||..|| ..|.|.::...:|.|:.:|...:.:..|.:|        ||.....:.|.
Mosquito   620 KKMMFNIATGAQEP-SPPFWTKKFPSFLYSYSVIFLFILLTIAAVFGIVVYRMSLMTSKNIYGDG 683

  Fly   442 KLPEESVLCCLSVIPKV-----LLAGAITLMDEAYFKLAVWLNDRENYRLQSKYENHLIAKVALF 501
                .||...|.:.|..     |||.  |.:..||..:|.::.:.|..|.|::|...|..|:.||
Mosquito   684 ----GSVSGKLIIFPATTAAINLLAS--TALTYAYQYVAEYMTNVEYRRTQTEYNESLNLKIYLF 742

  Fly   502 QFVNSFLSLFYIAF----------------YLRDEE--------KLKEQLAGLLISRQIIGNLRE 542
            :|||.:.|:|||||                :||.||        :|..|||.:::.:|.||.:.|
Mosquito   743 EFVNYYSSIFYIAFMKGKFPGYPAKYNRILHLRQEECSPGGCLMELCIQLAIIMVGKQAIGAITE 807

  Fly   543 SAIPYFLEQWKLAKLSFNMWGALSPTQNVTRSLAEELATAEAELKAESTGTPTKSQQPESSSKRN 607
            ..||:.::::|                .....|..:..:||...:.......||.....:...|:
Mosquito   808 ILIPFLVQKFK----------------EFRSVLGIDAGSAENGERLICCNQWTKDFNLINWHDRS 856

  Fly   608 IGQAEIESSLYKYDGTFSDHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQR 672
            :               |:::|:|::|.|::.:|..|||||...||:||:.|.|.||.|....::|
Mosquito   857 L---------------FNEYLKMVIQYGFITIFVVAFPLAPFFALLNNVFETRLDAKKFLLYYKR 906

  Fly   673 PFGQRVANIGTWQNALSILSLAAVIVNCALIGLSGQ-VSRL------------------------ 712
            ...|||.::|.|.|.:.::...|||.:..:|..|.. :.||
Mosquito   907 AVPQRVRDLGIWYNIMHVVGKVAVISSAFIIAFSSNFIPRLMYMNVVNPTGTDEGFVNHTLAYFN 971

  Fly   713 ------------------------------------------WPGLTTAQTIILIVTLEHIMLGL 735
                                                      |..|....|.::|  .::::..:
Mosquito   972 VSHFEANAAPENSTFSNITICRYSEYRNPPDDPRPYKRPSIYWQILAIRLTFVVI--YQNLVSFV 1034

  Fly   736 RQALTWLLPELPSWLAAEIARAEHCRRE---------MQCKGTSPRPTPPTPQSTTSTQPEQEGP 791
            :..:.|.:|::|:.|..:|.|.::...|         |...||.                   |.
Mosquito  1035 QIVVAWAIPDVPTKLQDQIKREQYLTNEYIIEQEKLKMALSGTG-------------------GC 1080

  Fly   792 GGL--------QMESGANTTRDQSMESQVAEDILLYGQEFAGYGHNIEADVNIYENRDSSPDSPP 848
            ||:        ..::|...:.|.|.:           .|.|.||.  .||.|.|..|..:.|..|
Mosquito  1081 GGVGGSVAGTRYAQNGCVASEDSSPD-----------DEKANYGS--IADDNEYPLRMQTDDCEP 1132

  Fly   849  848
            Mosquito  1133  1132

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wwk	NP_609738.1	Anoctamin	289..756	CDD:461349	158/617 (26%)
LOC1272176	XP_061511232.1	None