Protein Alignment CG15270 and Ano6

DIOPT Version :9

• Sequence 1: NP_609738.1
• Gene: CG15270 / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: NP_001240742.1
• Gene: Ano6 / 105722
• MGIID: 2145890
• Length: 932
• Species: Mus musculus
• Alignment Length: 932
• Identity: 204/932 - (21%)
• Similarity: 326/932 - (34%)
• Gaps: 346/932 - (37%)

  Fly    48 EDDFTDDNNFESNLRRRKGKIISCAKETIENASRQLRRKVPYAGHLMTPRRLWLNKIPTQC-DVV 111
            ||:...:||       :||           ...:|.|::..|..:|:             | .:.
Mouse    99 EDESKKENN-------KKG-----------TNEKQKRKRQAYESNLI-------------CHGLQ 132

  Fly   112 IEFPEDAPDEALRWLLARIRSQPPAGLGLLVQVKAHESTRRNAFYVSAPVNVLFKAAEEARLPKR 176
            :|......|:.                  ||.||.|           ||..||...||...:...
Mouse   133 LEATRSVSDDK------------------LVFVKVH-----------APWEVLCTYAEIMHIKLP 168

  Fly   177 LRP-DLG-----GALREFT----TRESHC----------FQQLRGD----VGSTALFTSQERQWL 217
            |:| ||.     |.|..||    ..||..          |::.|.:    :...:.|....|..:
Mouse   169 LKPNDLKTRSPFGNLNWFTKVLRVNESVIKPEQEFFTAPFEKSRMNDFYILDRDSFFNPATRSRI 233

  Fly   218 VLQVLQGLRAGCSDIEALHGRAAVAEGQSIVATWQESGLITQVFPLHE------------PSSLT 270
            |..:|..::....:.....|          :.....||:....||||:            ||...
Mouse   234 VYFILSRVKYQVMNNVNKFG----------INRLVSSGIYKAAFPLHDCRFNYESEDISCPSERY 288

  Fly   271 QLQTHWV--KQIFAPQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGT--ILY--------- 322
            .|...|.  :.|:..||||.|..|:|.|:.:||||||:||..|.:.||.|.  .||
Mouse   289 LLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLDQDNCT 353

  Fly   323 -----------------------CILWGKGQTAQ---------DMGHVLFSLFNVAWASLYLEAW 355
                                   |..|....|.:         ..|.::|::|...|.:|:||.|
Mouse   354 WSKEVCDPDIGGQILMCPQCDRLCPFWRLNITCESSKKLCIFDSFGTLIFAVFMGVWVTLFLEFW 418

  Fly   356 KRYSVELAFRWGTLSTPPELLEPPRPLYKGPLEE---NNVTGRLEPKEAPAWQRRAFRYLVSFPI 417
            ||...||.:.|.|:....|  |..||.|:.....   |.:|...|              .:.|..
Mouse   419 KRRQAELEYEWDTVELQQE--EQARPEYEAQCNHVVINEITQEEE--------------RIPFTT 467

  Fly   418 IGCCLCVVF---AVMFLML------------RFQDW--WDSKLPEE-----------SVLCCLSV 454
            .|.|:.|..   ||.|.:|            |...:  :.:.||:.           :.....|:
Mouse   468 CGKCIRVTLCASAVFFWILLIIASVIGIIVYRLSVFIVFSTTLPKNPNGTDPIQKYLTPQMATSI 532

  Fly   455 IPKVLLAGAITLMDEAYFKLAVWLNDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAFY--- 516
            ...::....|.:::..|.|:|:.:.:.|..|.|:.|||.|..|:.||||||.:.|.|||||:
Mouse   533 TASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGK 597

  Fly   517 --------------LRDEE--------KLKEQLAGLLISRQIIGNLRESAIPYFLEQWKLAKLSF 559
                          .|.||        :|..||..::..:.|..|::|..:|:.:
Mouse   598 FVGYPGDPVYLLGKYRSEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWVM---------- 652

  Fly   560 NMWGALSPTQNVTRSLAEELATAEAELKAESTGTPTKSQ----QPESSSKRNIGQAEIESSLYKY 620
            |:.|.....     |.:|::             ||...|    ||       :|:.
Mouse   653 NLIGRYKRV-----SGSEKI-------------TPRWEQDYHLQP-------MGKL--------- 683

  Fly   621 DGTFSDHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQ 685
             |.|.::|||::|.|:|.||.|:||||.:.||:||::|||.||:||....:|...::..:||.||
Mouse   684 -GLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDIGAWQ 747

  Fly   686 NALSILSLAAVIVNCALIGL-SGQVSRL---W--------------------------------- 713
            ..:..:::.||:.|..:|.. |..:.||   |
Mouse   748 PIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSIPPYGDHTYYTMDGYINNTLSVFNITDFKN 812

  Fly   714 ------------------------PG------------LTTAQTIILIVTLEHIMLGLRQALTWL 742
                                    ||            ...|..:..|:.:|||:..::..:::.
Mouse   813 TDKENPYIGLGNYTLCRYRDFRNPPGHPQEYKHNIYYWHVIAAKLAFIIVMEHIIYSVKFFISYA 877

  Fly   743 LPELPSWLAAEIARAEHCRREM 764
            :|::.....::|.|.::..:::
Mouse   878 IPDVSKITKSKIKREKYLTQKL 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	148/644 (23%)
Ano6	NP_001240742.1	Anoct_dimer	84..306	CDD:292796	53/276 (19%)
		Anoctamin	309..893	CDD:282414	148/644 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920