Protein Alignment CG15270 and ano3

DIOPT Version :9

• Sequence 1: NP_609738.1
• Gene: CG15270 / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_031756440.1
• Gene: ano3 / 100495805
• XenbaseID: XB-GENE-1012403
• Length: 983
• Species: Xenopus tropicalis
• Alignment Length: 980
• Identity: 219/980 - (22%)
• Similarity: 352/980 - (35%)
• Gaps: 337/980 - (34%)

  Fly    44 RDGGEDDFTDDNN-------------FESNLRRRK--GKIISCAKETIENASRQLRRKVPYAG-- 91
            ||..:|.:|||:.             .:..|.|:|  .:....:||.:.|..:.:..:.|.|.
 Frog    78 RDSTKDTYTDDSEHGAYDSRTDQSLLIQHKLTRQKQGSRKSQKSKEDLLNKEKHIFERFPTAPVQ 142

  Fly    92 ---HLMTPRRLWLNKIPTQCDVVIEFPEDAPDEALRWLLAR-IRSQPPAGLGLLVQVKAHESTRR 152
               ..:....|:......:.|.::.:.:.:.....|....: :|::     ||::: :.|..|..
 Frog   143 DEVGTVASLGLFFKDGMKRIDYILVYKKSSAQLEKRSTFEKNLRAE-----GLMLE-REHAITNN 201

  Fly   153 NAFYVS--APVNVLFKAAEE---------------------------------------ARLPKR 176
            :..:|.  .|.:.|.|.||.                                       .:|.|.
 Frog   202 DIMFVKIHCPWDTLCKYAERMNIRMPFRKKCYYTDWRSKTMGSLQRNMRQLKSWLPRNPMKLDKE 266

  Fly   177 LRPDLGGA---LREFTTRESHCFQQLRGDVGSTALFTSQERQWLVLQVLQGLRAGCSDIEALHGR 238
            ..|||...   ...|:....|.|.....|    ..|::..|..:|..|||              |
 Frog   267 ALPDLEETDCYTAPFSRARMHHFTINNKD----TFFSNSTRSRIVHHVLQ--------------R 313

  Fly   239 AAVAEGQSI--VATWQESGLITQVFPLHEPS--SLTQLQTH------------------WVKQIF 281
            ....:|:|.  ::....:|.....||.||.|  |...::||                  |.|.
 Frog   314 TKYEDGKSKMGISRLLSNGTYEAAFPPHEGSYKSRHPIKTHGAQNHRHLLYERWARWGMWYKY-- 376

  Fly   282 APQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILYCILWG-----KGQTAQDM------ 335
              ||||.|..|||.|:.|||||||.||..|...|:.|  |:..|:|     ..|.::::
 Frog   377 --QPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVG--LFVFLYGLFTMDSSQVSKEICEANET 437

  Fly   336 -------------------------------GHVLFSLFNVAWASLYLEAWKRYSVELAFRWGTL 369
                                           |.|.|::|...||:::||.|||....|.:.|..:
 Frog   438 IMCPMCEKNCSLQRLNESCIYAKVTHLFDNGGTVFFAIFMAIWATVFLEFWKRRRAVLTYDWDLI 502

  Fly   370 STPPELLEPPRPLYKGPLEE----NNVTGRLEPKEAPAWQRRAFRYLVS----FPIIGCCLCVVF 426
            ....| .|..||.::....:    |.:||:.||.:  .:..:..|.:||    |.:|...|..||
 Frog   503 DWEDE-EEELRPQFEAKYSQLERVNPITGKPEPFQ--PFSDKLSRLMVSVSGIFFMISLVLTAVF 564

  Fly   427 AV----MFLMLRF--------QDWWDSKLPEESVLCCLSVIPKVLLAGAITLMDEAYFKLAVWLN 479
            ||    :..|.:|        :.:|........|  |::.:       .|..::..|.|:|..|.
 Frog   565 AVVVYRLVAMEQFASFNWHFIKKYWQFATSGTGV--CINFM-------IIMSLNVVYEKVAYLLT 620

  Fly   480 DRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAFYL-----------------RDEE------ 521
            :.|:.|..|::||....|:.||||||...|:|||||:|                 |.||
 Frog   621 NLEHPRTDSEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFAGRPGKYNRLFQRWRLEECHPSGC 685

  Fly   522 --KLKEQLAGLLISRQIIGNLRESAIPYFLEQWKLAKLSFNMWGALSPTQNVTRSLAEELATAEA 584
              .|..|:..:::.:|:..|..|...| .|:.|         |                     :
 Frog   686 LIDLCLQMGVIMVLKQMWNNFMELGYP-LLQNW---------W---------------------S 719

  Fly   585 ELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKYD--GTFSDHLEMLVQMGYVVLFSAAFPLA 647
            ..|.:::|     |..|  :|..:.|.|.:.:|...:  |...::|||::|.|:..:|.||||||
 Frog   720 RRKIKNSG-----QMVE--NKFTLPQWEKDWNLQPMNAHGLMEEYLEMVIQFGFTTIFVAAFPLA 777

  Fly   648 GVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVIVNCALIG-------- 704
            .:.||:||::|||.||:|.....:||...|..:||.|...|..:.:.|||.|..:|.
 Frog   778 PLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWYGILEGIGVLAVITNAFVIAITSDYIPR 842

  Fly   705 --------------------LSGQVS--------------------------------------R 711
                                |.|.|:                                      :
 Frog   843 FVYAFKYGPCLDEGYRHEKCLQGYVNSSLSIFDLKELGQGYSGYCRYRDYREPPWSSNPYEFTLQ 907

  Fly   712 LWPGLTTAQTIILIVTLEHIMLGLRQALTWLLPELP----------SWLAAEI---ARAEHCRRE 763
            .|..|  |..:..|:..||::.|::..:.:|:|::|          .:|..|:   |..||.:||
 Frog   908 FWHVL--AARLAFIIVFEHLVFGIKSFIAYLIPDMPKDLCDRMRREKYLVQEMMYEAELEHLQRE 970

  Fly   764 MQCKG 768
            .:..|
 Frog   971 RKKNG 975

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	153/636 (24%)
ano3	XP_031756440.1	Anoct_dimer	154..379	CDD:406563	43/252 (17%)
		Anoctamin	382..951	CDD:398306	150/622 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1964
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.950